Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptors

Bibliographic Details
Main Author: Alexandre-Pires, G.
Publication Date: 2017
Other Authors: Martins, C., Galvão, A.M., Miranda, M., Silva, O., Ligeiro, D., Nunes, T., Ferreira-Dias, G.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://doi.org/10.3390/ijms18071516
Summary: info:eu-repo/grantAgreement/FCT/5876/147283/PT Funding for this work was provided by the Portuguese Foundation for Science and Technology (FCT) with co-participation of European Union Fund (FEDER) through the research project UID/CVT/00276/2013. The authors present special thanks to Sandra Carvalho and Rosario Luis (Histology Dept., FMV) and Gloria Nunes (Immunology Dept., FCM) for technical assistance.
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spelling Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptorsChemical compoundsESR1ESR2Inguinal sinusMorphologyPGRPRLRTranscriptionTriterpenoidsinfo:eu-repo/grantAgreement/FCT/5876/147283/PT Funding for this work was provided by the Portuguese Foundation for Science and Technology (FCT) with co-participation of European Union Fund (FEDER) through the research project UID/CVT/00276/2013. The authors present special thanks to Sandra Carvalho and Rosario Luis (Histology Dept., FMV) and Gloria Nunes (Immunology Dept., FCM) for technical assistance.Post-parturient behavior of mammalian females is essential for early parent–offspring contact. After delivery, lambs need to ingest colostrum for obtaining the related immunological protection, and early interactions between the mother and the lamb are crucial. Despite visual and auditory cues, olfactory cues are decisive in lamb orientation to the mammary gland. In sheep, the inguinal sinus is located bilaterally near the mammary gland as a skin pouch (IGS) that presents a gland that secretes a strong-smelling wax. Sheep IGS gland functions have many aspects under evaluation. The objective of the present study was to evaluate sheep IGS gland functional aspects and mRNA transcription and the protein expression of several hormone receptors, such as progesterone receptor (PGR), estrogen receptor 1 (ESR1), and 2 (ESR2) and prolactin receptor (PRLR) present. In addition, another aim was to achieve information about IGS ultrastructure and chemical compounds produced in this gland. All hormone receptors evaluated show expression in IGS during the estrous cycle (follicular/luteal phases), pregnancy, and the post-partum period. IGS secretion is rich in triterpenoids that totally differ from the surrounding skin. They might be essential substances for the development of an olfactory preference of newborns to their mothers. © 2017 by the authors. Licensee MDPI, Basel, Switzerland.Centro de Estudos de Doenças Crónicas (CEDOC)NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNAlexandre-Pires, G.Martins, C.Galvão, A.M.Miranda, M.Silva, O.Ligeiro, D.Nunes, T.Ferreira-Dias, G.2017-10-25T10:20:46Z2017-072017-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.3390/ijms18071516eng1661-6596PURE: 3229277https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028085731&doi=10.3390%2fijms18071516&partnerID=40&md5=0531dc1fe3869d6a89d2b9abb50bb013https://doi.org/10.3390/ijms18071516info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T17:28:19Zoai:run.unl.pt:10362/24573Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T16:59:24.109973Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptors
title Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptors
spellingShingle Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptors
Alexandre-Pires, G.
Chemical compounds
ESR1
ESR2
Inguinal sinus
Morphology
PGR
PRLR
Transcription
Triterpenoids
title_short Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptors
title_full Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptors
title_fullStr Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptors
title_full_unstemmed Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptors
title_sort Understanding the inguinal sinus in sheep (Ovis aries)—Morphology, secretion, and expression of progesterone, estrogens, and prolactin receptors
author Alexandre-Pires, G.
author_facet Alexandre-Pires, G.
Martins, C.
Galvão, A.M.
Miranda, M.
Silva, O.
Ligeiro, D.
Nunes, T.
Ferreira-Dias, G.
author_role author
author2 Martins, C.
Galvão, A.M.
Miranda, M.
Silva, O.
Ligeiro, D.
Nunes, T.
Ferreira-Dias, G.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Centro de Estudos de Doenças Crónicas (CEDOC)
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Alexandre-Pires, G.
Martins, C.
Galvão, A.M.
Miranda, M.
Silva, O.
Ligeiro, D.
Nunes, T.
Ferreira-Dias, G.
dc.subject.por.fl_str_mv Chemical compounds
ESR1
ESR2
Inguinal sinus
Morphology
PGR
PRLR
Transcription
Triterpenoids
topic Chemical compounds
ESR1
ESR2
Inguinal sinus
Morphology
PGR
PRLR
Transcription
Triterpenoids
description info:eu-repo/grantAgreement/FCT/5876/147283/PT Funding for this work was provided by the Portuguese Foundation for Science and Technology (FCT) with co-participation of European Union Fund (FEDER) through the research project UID/CVT/00276/2013. The authors present special thanks to Sandra Carvalho and Rosario Luis (Histology Dept., FMV) and Gloria Nunes (Immunology Dept., FCM) for technical assistance.
publishDate 2017
dc.date.none.fl_str_mv 2017-10-25T10:20:46Z
2017-07
2017-07-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.3390/ijms18071516
url https://doi.org/10.3390/ijms18071516
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1661-6596
PURE: 3229277
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028085731&doi=10.3390%2fijms18071516&partnerID=40&md5=0531dc1fe3869d6a89d2b9abb50bb013
https://doi.org/10.3390/ijms18071516
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833596348642885632

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