Is the MTHFR C677T polymorphism associated with obesity risk? – a meta-analysis.

Bibliographic Details
Main Author: Costa, J.
Publication Date: 2016
Other Authors: Oliveira, R., Prudêncio, Cristina, Fernandes, Rúben
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.22/23777
Summary: Overweight and obesity are a major worldwide health problem and its incidence is increasing every year. Methylenetetrahydrofolate reductase (MTHFR) plays an important role in folate metabolism and as a regulator of DNA methylation, synthesis, and repair. MTHFR gene is polymorphic at nucleotides 677 (C→T) and 1298 (A→C). MTHFR C677T polymorphism results in alloenzymes with decreased activity and several studies have pointed to association between the MTHFR C677T polymorphism and overweight/obesity risk.
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network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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spelling Is the MTHFR C677T polymorphism associated with obesity risk? – a meta-analysis.MTHFRC677TPolymorphismObesityRiskOverweight and obesity are a major worldwide health problem and its incidence is increasing every year. Methylenetetrahydrofolate reductase (MTHFR) plays an important role in folate metabolism and as a regulator of DNA methylation, synthesis, and repair. MTHFR gene is polymorphic at nucleotides 677 (C→T) and 1298 (A→C). MTHFR C677T polymorphism results in alloenzymes with decreased activity and several studies have pointed to association between the MTHFR C677T polymorphism and overweight/obesity risk.Sociedade Portuguesa de DiabetesREPOSITÓRIO P.PORTOCosta, J.Oliveira, R.Prudêncio, CristinaFernandes, Rúben2023-10-25T13:18:52Z2016-122016-12-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.22/23777eng1646-3994info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-07T10:16:45Zoai:recipp.ipp.pt:10400.22/23777Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:46:15.742564Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Is the MTHFR C677T polymorphism associated with obesity risk? – a meta-analysis.
title Is the MTHFR C677T polymorphism associated with obesity risk? – a meta-analysis.
spellingShingle Is the MTHFR C677T polymorphism associated with obesity risk? – a meta-analysis.
Costa, J.
MTHFR
C677T
Polymorphism
Obesity
Risk
title_short Is the MTHFR C677T polymorphism associated with obesity risk? – a meta-analysis.
title_full Is the MTHFR C677T polymorphism associated with obesity risk? – a meta-analysis.
title_fullStr Is the MTHFR C677T polymorphism associated with obesity risk? – a meta-analysis.
title_full_unstemmed Is the MTHFR C677T polymorphism associated with obesity risk? – a meta-analysis.
title_sort Is the MTHFR C677T polymorphism associated with obesity risk? – a meta-analysis.
author Costa, J.
author_facet Costa, J.
Oliveira, R.
Prudêncio, Cristina
Fernandes, Rúben
author_role author
author2 Oliveira, R.
Prudêncio, Cristina
Fernandes, Rúben
author2_role author
author
author
dc.contributor.none.fl_str_mv REPOSITÓRIO P.PORTO
dc.contributor.author.fl_str_mv Costa, J.
Oliveira, R.
Prudêncio, Cristina
Fernandes, Rúben
dc.subject.por.fl_str_mv MTHFR
C677T
Polymorphism
Obesity
Risk
topic MTHFR
C677T
Polymorphism
Obesity
Risk
description Overweight and obesity are a major worldwide health problem and its incidence is increasing every year. Methylenetetrahydrofolate reductase (MTHFR) plays an important role in folate metabolism and as a regulator of DNA methylation, synthesis, and repair. MTHFR gene is polymorphic at nucleotides 677 (C→T) and 1298 (A→C). MTHFR C677T polymorphism results in alloenzymes with decreased activity and several studies have pointed to association between the MTHFR C677T polymorphism and overweight/obesity risk.
publishDate 2016
dc.date.none.fl_str_mv 2016-12
2016-12-01T00:00:00Z
2023-10-25T13:18:52Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/23777
url http://hdl.handle.net/10400.22/23777
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1646-3994
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Diabetes
publisher.none.fl_str_mv Sociedade Portuguesa de Diabetes
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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