OMALIZUMAB IN SEVERE ATOPIC DERMATITIS

Bibliographic Details
Main Author: Luz, Sofia
Publication Date: 2011
Other Authors: Silva, Pedro, Costa, Ana Célia, Spínola Santos, Amélia, Pedro, Elisa, Pereira Barbosa, Manuel
Format: Article
Language: por
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://doi.org/10.29021/spdv.69.2.615
Summary: We present the cases of two young females with severe atopic dermatitis, treated with anti-histamines, topical corticosteroids, high-dose systemic corticosteroids bursts and/or oral cyclosporine, without significant improvement and worsening with tapering of corticosteroids and/or cyclosporine. Several therapeutical adjustments were made without success before starting treatment with subcutaneous omalizumab. The clinical evolution of these patients undergoing treatment with omalizumab is described and its role in the treatment of atopic dermatitis is discussed.
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spelling OMALIZUMAB IN SEVERE ATOPIC DERMATITISO PAPEL DO OMALIZUMAB NA DERMATITE ATÓPICA GRAVEOmalizumabSevere atopic dermatitisDermatite atópica graveOmalizumabWe present the cases of two young females with severe atopic dermatitis, treated with anti-histamines, topical corticosteroids, high-dose systemic corticosteroids bursts and/or oral cyclosporine, without significant improvement and worsening with tapering of corticosteroids and/or cyclosporine. Several therapeutical adjustments were made without success before starting treatment with subcutaneous omalizumab. The clinical evolution of these patients undergoing treatment with omalizumab is described and its role in the treatment of atopic dermatitis is discussed.Apresentam-se os casos de duas jovens, com diagnóstico de dermatite atópica grave medicadas com anti-histamínicos orais, corticóides tópicos, ciclos de corticoterapia sistémica em doses elevadas e/ou ciclosporina oral, sem melhoria e com agravamento clínico após redução da dose de corticóides sistémicos e/ou da ciclosporina. Na consulta de imunoalergologia efectuaram-se vários reajustes terapêuticos sem sucesso antes de iniciar terapêutica com omalizumab subcutâneo. Descreve-se a evolução clínica destas 2 doentes sob terapêutica com omalizumab e discute-se o seu papel no tratamento da dermatite atópica.Sociedade Portuguesa de Dermatologia e Venereologia2011-06-23T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.69.2.615oai:ojs.revista.spdv.com.pt:article/615Journal of the Portuguese Society of Dermatology and Venereology; Vol 69 No 2 (2011): Abril / Junho; 267-271Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 69 n. 2 (2011): Abril / Junho; 267-2712182-24092182-2395reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/615https://doi.org/10.29021/spdv.69.2.615https://revista.spdv.com.pt/index.php/spdv/article/view/615/437Luz, SofiaSilva, PedroCosta, Ana CéliaSpínola Santos, AméliaPedro, ElisaPereira Barbosa, Manuelinfo:eu-repo/semantics/openAccess2022-10-06T12:34:59Zoai:ojs.revista.spdv.com.pt:article/615Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T10:31:11.952397Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv OMALIZUMAB IN SEVERE ATOPIC DERMATITIS
O PAPEL DO OMALIZUMAB NA DERMATITE ATÓPICA GRAVE
title OMALIZUMAB IN SEVERE ATOPIC DERMATITIS
spellingShingle OMALIZUMAB IN SEVERE ATOPIC DERMATITIS
Luz, Sofia
Omalizumab
Severe atopic dermatitis
Dermatite atópica grave
Omalizumab
title_short OMALIZUMAB IN SEVERE ATOPIC DERMATITIS
title_full OMALIZUMAB IN SEVERE ATOPIC DERMATITIS
title_fullStr OMALIZUMAB IN SEVERE ATOPIC DERMATITIS
title_full_unstemmed OMALIZUMAB IN SEVERE ATOPIC DERMATITIS
title_sort OMALIZUMAB IN SEVERE ATOPIC DERMATITIS
author Luz, Sofia
author_facet Luz, Sofia
Silva, Pedro
Costa, Ana Célia
Spínola Santos, Amélia
Pedro, Elisa
Pereira Barbosa, Manuel
author_role author
author2 Silva, Pedro
Costa, Ana Célia
Spínola Santos, Amélia
Pedro, Elisa
Pereira Barbosa, Manuel
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Luz, Sofia
Silva, Pedro
Costa, Ana Célia
Spínola Santos, Amélia
Pedro, Elisa
Pereira Barbosa, Manuel
dc.subject.por.fl_str_mv Omalizumab
Severe atopic dermatitis
Dermatite atópica grave
Omalizumab
topic Omalizumab
Severe atopic dermatitis
Dermatite atópica grave
Omalizumab
description We present the cases of two young females with severe atopic dermatitis, treated with anti-histamines, topical corticosteroids, high-dose systemic corticosteroids bursts and/or oral cyclosporine, without significant improvement and worsening with tapering of corticosteroids and/or cyclosporine. Several therapeutical adjustments were made without success before starting treatment with subcutaneous omalizumab. The clinical evolution of these patients undergoing treatment with omalizumab is described and its role in the treatment of atopic dermatitis is discussed.
publishDate 2011
dc.date.none.fl_str_mv 2011-06-23T00:00:00Z
dc.type.driver.fl_str_mv journal article
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.69.2.615
oai:ojs.revista.spdv.com.pt:article/615
url https://doi.org/10.29021/spdv.69.2.615
identifier_str_mv oai:ojs.revista.spdv.com.pt:article/615
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/615
https://doi.org/10.29021/spdv.69.2.615
https://revista.spdv.com.pt/index.php/spdv/article/view/615/437
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 69 No 2 (2011): Abril / Junho; 267-271
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 69 n. 2 (2011): Abril / Junho; 267-271
2182-2409
2182-2395
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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