European guidelines on perinatal care: corticosteroids for women at risk of preterm birth
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
| Texto Completo: | http://hdl.handle.net/10451/56304 |
Resumo: | © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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European guidelines on perinatal care: corticosteroids for women at risk of preterm birthCorticosteroidsAntenatalGuidelinePreterm birth© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Summary of recommendations Corticosteroids should be administered to women at a gestational age between 24+0 and 33+6 weeks, when preterm birth is anticipated in the next seven days, as these have been consistently shown to reduce neonatal mortality and morbidity. (Strong-quality evidence; strong recommendation). In selected cases, extension of this period up to 34+6 weeks may be considered (Expert opinion). Optimal benefits are found in infants delivered within 7 days of corticosteroid administration. Even a single-dose administration should be given to women with imminent preterm birth, as this is likely to improve neurodevelopmental outcome (Moderate-quality evidence; conditional recommendation). Either betamethasone (12 mg administered intramuscularly twice, 24-hours apart) or dexamethasone (6 mg administered intramuscularly in four doses, 12-hours apart, or 12 mg administered intramuscularly twice, 24-hours apart), may be used (Moderate-quality evidence; Strong recommendation). Administration of two “all” doses is named a “course of corticosteroids”. Administration between 22+0 and 23+6 weeks should be considered when preterm birth is anticipated in the next seven days and active newborn life-support is indicated, taking into account parental wishes. Clear survival benefit has been observed in these cases, but the impact on short-term neurological and respiratory function, as well as long-term neurodevelopmental outcome is still unclear (Low/moderate-quality evidence; Weak recommendation). Administration between 34 + 0 and 34 + 6 weeks should only be offered to a few selected cases (Expert opinion). Administration between 35+0 and 36+6 weeks should be restricted to prospective randomized trials. Current evidence suggests that although corticosteroids reduce the incidence of transient tachypnea of the newborn, they do not affect the incidence of respiratory distress syndrome, and they increase neonatal hypoglycemia. Long-term safety data are lacking (Moderate quality evidence; Conditional recommendation). Administration in pregnancies beyond 37+0 weeks is not indicated, even for scheduled cesarean delivery, as current evidence does not suggest benefit and the long-term effects remain unknown (Low-quality evidence; Conditional recommendation). Administration should be given in twin pregnancies, with the same indication and doses as for singletons. However, existing evidence suggests that it should be reserved for pregnancies at high-risk of delivering within a 7-day interval (Low-quality evidence; Conditional recommendation). Maternal diabetes mellitus is not a contraindication to the use of antenatal corticosteroids (Moderate quality evidence; Strong recommendation). A single repeat course of corticosteroids can be considered in pregnancies at less than 34+0 weeks gestation, if the previous course was completed more than seven days earlier, and there is a renewed risk of imminent delivery (Low-quality evidence; Conditional recommendation).Taylor & FrancisRepositório da Universidade de LisboaDaskalakis, GeorgePergialiotis, VasiliosDomellöf, MagnusEhrhardt, HaraldDi Renzo, Gian CarloKoç, EsinMalamitsi-Puchner, AriadneKacerovsky, MarianModi, NeenaShennan, AndrewAyres-de-Campos, DiogoGliozheni, ElkoRull, KristiinaBraun, ThorstenBeke, ArturKosińska-Kaczyńska, KatarzynaAreia, Ana LuisaVladareanu, SimonaSršen, Tanja PremruSchmitz, ThomasJacobsson, Bo2023-02-14T14:54:19Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/56304engJ Matern Fetal Neonatal Med. 2023 Dec;36(1):21606281476-705810.1080/14767058.2022.21606281476-4954info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T14:53:54Zoai:repositorio.ulisboa.pt:10451/56304Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:28:07.560310Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
| dc.title.none.fl_str_mv |
European guidelines on perinatal care: corticosteroids for women at risk of preterm birth |
| title |
European guidelines on perinatal care: corticosteroids for women at risk of preterm birth |
| spellingShingle |
European guidelines on perinatal care: corticosteroids for women at risk of preterm birth Daskalakis, George Corticosteroids Antenatal Guideline Preterm birth |
| title_short |
European guidelines on perinatal care: corticosteroids for women at risk of preterm birth |
| title_full |
European guidelines on perinatal care: corticosteroids for women at risk of preterm birth |
| title_fullStr |
European guidelines on perinatal care: corticosteroids for women at risk of preterm birth |
| title_full_unstemmed |
European guidelines on perinatal care: corticosteroids for women at risk of preterm birth |
| title_sort |
European guidelines on perinatal care: corticosteroids for women at risk of preterm birth |
| author |
Daskalakis, George |
| author_facet |
Daskalakis, George Pergialiotis, Vasilios Domellöf, Magnus Ehrhardt, Harald Di Renzo, Gian Carlo Koç, Esin Malamitsi-Puchner, Ariadne Kacerovsky, Marian Modi, Neena Shennan, Andrew Ayres-de-Campos, Diogo Gliozheni, Elko Rull, Kristiina Braun, Thorsten Beke, Artur Kosińska-Kaczyńska, Katarzyna Areia, Ana Luisa Vladareanu, Simona Sršen, Tanja Premru Schmitz, Thomas Jacobsson, Bo |
| author_role |
author |
| author2 |
Pergialiotis, Vasilios Domellöf, Magnus Ehrhardt, Harald Di Renzo, Gian Carlo Koç, Esin Malamitsi-Puchner, Ariadne Kacerovsky, Marian Modi, Neena Shennan, Andrew Ayres-de-Campos, Diogo Gliozheni, Elko Rull, Kristiina Braun, Thorsten Beke, Artur Kosińska-Kaczyńska, Katarzyna Areia, Ana Luisa Vladareanu, Simona Sršen, Tanja Premru Schmitz, Thomas Jacobsson, Bo |
| author2_role |
author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
| dc.contributor.author.fl_str_mv |
Daskalakis, George Pergialiotis, Vasilios Domellöf, Magnus Ehrhardt, Harald Di Renzo, Gian Carlo Koç, Esin Malamitsi-Puchner, Ariadne Kacerovsky, Marian Modi, Neena Shennan, Andrew Ayres-de-Campos, Diogo Gliozheni, Elko Rull, Kristiina Braun, Thorsten Beke, Artur Kosińska-Kaczyńska, Katarzyna Areia, Ana Luisa Vladareanu, Simona Sršen, Tanja Premru Schmitz, Thomas Jacobsson, Bo |
| dc.subject.por.fl_str_mv |
Corticosteroids Antenatal Guideline Preterm birth |
| topic |
Corticosteroids Antenatal Guideline Preterm birth |
| description |
© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| publishDate |
2023 |
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2023-02-14T14:54:19Z 2023 2023-01-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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publishedVersion |
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http://hdl.handle.net/10451/56304 |
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| dc.language.iso.fl_str_mv |
eng |
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eng |
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J Matern Fetal Neonatal Med. 2023 Dec;36(1):2160628 1476-7058 10.1080/14767058.2022.2160628 1476-4954 |
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Taylor & Francis |
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Taylor & Francis |
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