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Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism

Bibliographic Details
Main Author: Caldevilla, Renato
Publication Date: 2023
Other Authors: Santos, Marlene, Barroso, M. Fátima
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.22/25755
Summary: Major depression disorder (MDD) is the most prevalent psychiatric condition worldwide. Currently, antidepressants constitute the main pharmacological treatment for this condition. Despite the growing arsenal of antidepressant medications, almost half of MDD patients have insufficient remission rates during their treatments. A growing body of scientific evidence points to genetic factors as having a crucial role in patients’ response to antidepressant treatments. One of these genetic components is the BDNF gene, that codes for the BDNF neurotrophin, an important player in neuroplasticity and neurogenesis.
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spelling Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphismMajor depression disorderBDNF geneMajor depression disorder (MDD) is the most prevalent psychiatric condition worldwide. Currently, antidepressants constitute the main pharmacological treatment for this condition. Despite the growing arsenal of antidepressant medications, almost half of MDD patients have insufficient remission rates during their treatments. A growing body of scientific evidence points to genetic factors as having a crucial role in patients’ response to antidepressant treatments. One of these genetic components is the BDNF gene, that codes for the BDNF neurotrophin, an important player in neuroplasticity and neurogenesis.Sociedade Portuguesa de QuímicaREPOSITÓRIO P.PORTOCaldevilla, RenatoSantos, MarleneBarroso, M. Fátima2024-07-09T13:21:48Z2023-112023-11-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.22/25755eng978-989-8124-40-1978-989-8124-39-5info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-07T10:32:32Zoai:recipp.ipp.pt:10400.22/25755Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T01:00:28.319945Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism
title Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism
spellingShingle Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism
Caldevilla, Renato
Major depression disorder
BDNF gene
title_short Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism
title_full Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism
title_fullStr Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism
title_full_unstemmed Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism
title_sort Construction and optimization of an electrochemical genosensor for the detection of BDNF gene Val66Met polymorphism
author Caldevilla, Renato
author_facet Caldevilla, Renato
Santos, Marlene
Barroso, M. Fátima
author_role author
author2 Santos, Marlene
Barroso, M. Fátima
author2_role author
author
dc.contributor.none.fl_str_mv REPOSITÓRIO P.PORTO
dc.contributor.author.fl_str_mv Caldevilla, Renato
Santos, Marlene
Barroso, M. Fátima
dc.subject.por.fl_str_mv Major depression disorder
BDNF gene
topic Major depression disorder
BDNF gene
description Major depression disorder (MDD) is the most prevalent psychiatric condition worldwide. Currently, antidepressants constitute the main pharmacological treatment for this condition. Despite the growing arsenal of antidepressant medications, almost half of MDD patients have insufficient remission rates during their treatments. A growing body of scientific evidence points to genetic factors as having a crucial role in patients’ response to antidepressant treatments. One of these genetic components is the BDNF gene, that codes for the BDNF neurotrophin, an important player in neuroplasticity and neurogenesis.
publishDate 2023
dc.date.none.fl_str_mv 2023-11
2023-11-01T00:00:00Z
2024-07-09T13:21:48Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/25755
url http://hdl.handle.net/10400.22/25755
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 978-989-8124-40-1
978-989-8124-39-5
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Química
publisher.none.fl_str_mv Sociedade Portuguesa de Química
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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