Primary mucosal malignant melanoma of the head and neck - Experience from the Portuguese Institute of Oncology in Lisbon

Bibliographic Details
Main Author: Durão, Carolina
Publication Date: 2015
Other Authors: Pimentel, João, Hebe, Ana, Pacheco, Ricardo, Montalvão, Pedro, Magalhães, Miguel
Format: Article
Language: por
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://doi.org/10.34631/sporl.595
Summary: Introduction: Mucosal melanoma of the head and neck is an uncommon disease with poor prognosis.Material and Methods: Retrospective chart review of 32 patients treated for head and neck mucosal melanoma in a cancer center from 1998 to 2012.Results: There were 32 cases with an average age of 70. The primary tumor was located in the nasal cavity in 24 patients and in the oral cavity in 8 patients. The majority of patients (23) underwent surgical treatment. Of these, 16 were proposed for adjunctive therapy with radiotherapy. Follow-up time ranged between 26 days to 10 years. The five year survival rate was 18%.Conclusions: The majority of patients had an advanced stage at diagnosis and despite the treatments here was a high rate of mortality. The treatment of choice is surgery. The role of radiation therapy remains controversial. 
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spelling Primary mucosal malignant melanoma of the head and neck - Experience from the Portuguese Institute of Oncology in LisbonMelanoma maligno da mucosa da cabeça e pescoço - Casuística do IPO de LisboaMucosal malignant melanomanasal sinusesoral cavityMelanoma maligno da mucosaseios perinasaiscavidade oralIntroduction: Mucosal melanoma of the head and neck is an uncommon disease with poor prognosis.Material and Methods: Retrospective chart review of 32 patients treated for head and neck mucosal melanoma in a cancer center from 1998 to 2012.Results: There were 32 cases with an average age of 70. The primary tumor was located in the nasal cavity in 24 patients and in the oral cavity in 8 patients. The majority of patients (23) underwent surgical treatment. Of these, 16 were proposed for adjunctive therapy with radiotherapy. Follow-up time ranged between 26 days to 10 years. The five year survival rate was 18%.Conclusions: The majority of patients had an advanced stage at diagnosis and despite the treatments here was a high rate of mortality. The treatment of choice is surgery. The role of radiation therapy remains controversial. Introdução: O melanoma maligno da mucosa (MMM) é uma doença rara com mau prognóstico.Material e Métodos: Estudo retrospetivo de 32 doentes do Instituto Português de Oncologia Francisco Gentil de Lisboa com MMM da cabeça e pescoço, no período de 1998 a 2012.Resultados: Dos 32 casos analisados a idade média foi de 70 anos. O tumor primário localizou-se na cavidade nasal e seios peri-nasais em 24 doentes e na cavidade oral em 8 casos. A maioria dos doentes (23) foi submetida a tratamento cirúrgico. Destes, 16 foram propostos para terapêutica complementar com Radioterapia. O tempo de seguimento variou de 26 dias a 10 anos. A sobrevida aos 5 anos foi de 18%.Conclusões: A maioria dos doentes apresentou um estadio avançado na altura do diagnóstico e, apesar dos tratamentos instituídos, verificou-se uma elevada mortalidade. O tratamento de escolha é a cirurgia. O papel da radioterapia continua a ser controverso.Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço2015-12-11info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.34631/sporl.595https://doi.org/10.34631/sporl.595Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 53 No. 3 (2015): Setembro; 167-171Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 53 Núm. 3 (2015): Setembro; 167-171Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 53 N.º 3 (2015): Setembro; 167-1712184-6499reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporhttps://journalsporl.com/index.php/sporl/article/view/2762https://journalsporl.com/index.php/sporl/article/view/2762/764Durão, CarolinaPimentel, JoãoHebe, AnaPacheco, RicardoMontalvão, PedroMagalhães, Miguelinfo:eu-repo/semantics/openAccess2024-06-06T13:00:12Zoai:journalsporl.com:article/2762Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:54:24.315143Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Primary mucosal malignant melanoma of the head and neck - Experience from the Portuguese Institute of Oncology in Lisbon
Melanoma maligno da mucosa da cabeça e pescoço - Casuística do IPO de Lisboa
title Primary mucosal malignant melanoma of the head and neck - Experience from the Portuguese Institute of Oncology in Lisbon
spellingShingle Primary mucosal malignant melanoma of the head and neck - Experience from the Portuguese Institute of Oncology in Lisbon
Durão, Carolina
Mucosal malignant melanoma
nasal sinuses
oral cavity
Melanoma maligno da mucosa
seios perinasais
cavidade oral
title_short Primary mucosal malignant melanoma of the head and neck - Experience from the Portuguese Institute of Oncology in Lisbon
title_full Primary mucosal malignant melanoma of the head and neck - Experience from the Portuguese Institute of Oncology in Lisbon
title_fullStr Primary mucosal malignant melanoma of the head and neck - Experience from the Portuguese Institute of Oncology in Lisbon
title_full_unstemmed Primary mucosal malignant melanoma of the head and neck - Experience from the Portuguese Institute of Oncology in Lisbon
title_sort Primary mucosal malignant melanoma of the head and neck - Experience from the Portuguese Institute of Oncology in Lisbon
author Durão, Carolina
author_facet Durão, Carolina
Pimentel, João
Hebe, Ana
Pacheco, Ricardo
Montalvão, Pedro
Magalhães, Miguel
author_role author
author2 Pimentel, João
Hebe, Ana
Pacheco, Ricardo
Montalvão, Pedro
Magalhães, Miguel
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Durão, Carolina
Pimentel, João
Hebe, Ana
Pacheco, Ricardo
Montalvão, Pedro
Magalhães, Miguel
dc.subject.por.fl_str_mv Mucosal malignant melanoma
nasal sinuses
oral cavity
Melanoma maligno da mucosa
seios perinasais
cavidade oral
topic Mucosal malignant melanoma
nasal sinuses
oral cavity
Melanoma maligno da mucosa
seios perinasais
cavidade oral
description Introduction: Mucosal melanoma of the head and neck is an uncommon disease with poor prognosis.Material and Methods: Retrospective chart review of 32 patients treated for head and neck mucosal melanoma in a cancer center from 1998 to 2012.Results: There were 32 cases with an average age of 70. The primary tumor was located in the nasal cavity in 24 patients and in the oral cavity in 8 patients. The majority of patients (23) underwent surgical treatment. Of these, 16 were proposed for adjunctive therapy with radiotherapy. Follow-up time ranged between 26 days to 10 years. The five year survival rate was 18%.Conclusions: The majority of patients had an advanced stage at diagnosis and despite the treatments here was a high rate of mortality. The treatment of choice is surgery. The role of radiation therapy remains controversial. 
publishDate 2015
dc.date.none.fl_str_mv 2015-12-11
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.34631/sporl.595
https://doi.org/10.34631/sporl.595
url https://doi.org/10.34631/sporl.595
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://journalsporl.com/index.php/sporl/article/view/2762
https://journalsporl.com/index.php/sporl/article/view/2762/764
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço
publisher.none.fl_str_mv Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço
dc.source.none.fl_str_mv Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 53 No. 3 (2015): Setembro; 167-171
Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 53 Núm. 3 (2015): Setembro; 167-171
Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 53 N.º 3 (2015): Setembro; 167-171
2184-6499
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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