Immunotherapy of aspergillosis

Bibliographic Details
Main Author: Carvalho, Agostinho
Publication Date: 2012
Other Authors: Cunha, Cristina, Bistoni, Francesco, Romani, Luigina
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/1822/23815
Summary: We thank C. M. Benedetti for digital art and editing.
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spelling Immunotherapy of aspergillosisAspergillosisImmunotherapySingle-nucleotide polymorphismScience & TechnologyWe thank C. M. Benedetti for digital art and editing.Management of invasive aspergillosis in high-risk patients remains challenging. There is an increasing demand for novel therapeutic strategies aimed at enhancing or restoring antifungal immunity in immunocompromised patients. In this regard, modulation of specific innate immune functions and vaccination are promising immunotherapeutic strategies. Recent findings have also provided a compelling rationale for assessment of the contribution of the individual genetic profile to the immunotherapy outcome. Altogether, integration of immunological and genetic data may contribute to the optimization of therapeutic strategies exerting control over immune pathways, ultimately improving the management of fungal infections in high-risk settings.The studies were supported by the Specific Targeted Research Project ALLFUN (FP7-HEALTH-2009 contract number 260338 to L. Romani) and by the Fondazione per la Ricerca sulla Fibrosi Cistica (FFC#21/2010 to L. Romani, with the contribution of Francesca Guadagnin, Coca Cola light Tribute to Fashion and Delegazione FFC di Belluno). C. Cunha and A. Carvalho were financially supported by fellowships from Fundação para a Ciência e Tecnologia, Portugal (contracts SFRH/ BD/65962/2009 and SFRH/BPD/46292/2008, respectively).Wiley-BlackwellUniversidade do MinhoCarvalho, AgostinhoCunha, CristinaBistoni, FrancescoRomani, Luigina2012-022012-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/23815eng1198-743X10.1111/j.1469-0691.2011.03681.x22023729http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2011.03681.x/pdfinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T07:24:28Zoai:repositorium.sdum.uminho.pt:1822/23815Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T16:26:08.300916Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Immunotherapy of aspergillosis
title Immunotherapy of aspergillosis
spellingShingle Immunotherapy of aspergillosis
Carvalho, Agostinho
Aspergillosis
Immunotherapy
Single-nucleotide polymorphism
Science & Technology
title_short Immunotherapy of aspergillosis
title_full Immunotherapy of aspergillosis
title_fullStr Immunotherapy of aspergillosis
title_full_unstemmed Immunotherapy of aspergillosis
title_sort Immunotherapy of aspergillosis
author Carvalho, Agostinho
author_facet Carvalho, Agostinho
Cunha, Cristina
Bistoni, Francesco
Romani, Luigina
author_role author
author2 Cunha, Cristina
Bistoni, Francesco
Romani, Luigina
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Carvalho, Agostinho
Cunha, Cristina
Bistoni, Francesco
Romani, Luigina
dc.subject.por.fl_str_mv Aspergillosis
Immunotherapy
Single-nucleotide polymorphism
Science & Technology
topic Aspergillosis
Immunotherapy
Single-nucleotide polymorphism
Science & Technology
description We thank C. M. Benedetti for digital art and editing.
publishDate 2012
dc.date.none.fl_str_mv 2012-02
2012-02-01T00:00:00Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/23815
url http://hdl.handle.net/1822/23815
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1198-743X
10.1111/j.1469-0691.2011.03681.x
22023729
http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2011.03681.x/pdf
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