A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma

Bibliographic Details
Main Author: Ramos, R
Publication Date: 2018
Other Authors: Fernandes, JS, Almeida, M, Almeida, R
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.23/1317
Summary: Primary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of the central nervous system as well as its subsequent reappearance in another location. The atypical presentation misled the neurosurgeons and neurologists, delaying diagnosis and treatment. The patient underwent brain biopsy after the relapse and started radiotherapy and chemotherapy with cytarabine + methotrexate + rituximab. As of 32 months after the diagnosis, the patient remained asymptomatic, with no focal neurological deficits and the disease in complete remission. A PubMed search of the literature up to June 2017 regarding spontaneous remission central nervous system lymphoma was also carried out.
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spelling A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System LymphomaLinfoma/quimioterapiaLinfoma/radioterapiaNeoplasias do Sistema Nervoso Central/quimioterapiaNeoplasias do Sistema Nervoso Central/radioterapiaPrimary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of the central nervous system as well as its subsequent reappearance in another location. The atypical presentation misled the neurosurgeons and neurologists, delaying diagnosis and treatment. The patient underwent brain biopsy after the relapse and started radiotherapy and chemotherapy with cytarabine + methotrexate + rituximab. As of 32 months after the diagnosis, the patient remained asymptomatic, with no focal neurological deficits and the disease in complete remission. A PubMed search of the literature up to June 2017 regarding spontaneous remission central nervous system lymphoma was also carried out.Repositório Científico do Hospital de BragaRamos, RFernandes, JSAlmeida, MAlmeida, R2019-03-01T14:13:09Z2018-12-28T00:00:00Z2018-12-28T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.23/1317engActa Med Port. 2018 Dec 28;31(12):777-783.10.20344/amp.10198info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2022-09-21T09:03:13Zoai:repositorio.hospitaldebraga.pt:10400.23/1317Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T10:16:20.164246Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
title A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
spellingShingle A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
Ramos, R
Linfoma/quimioterapia
Linfoma/radioterapia
Neoplasias do Sistema Nervoso Central/quimioterapia
Neoplasias do Sistema Nervoso Central/radioterapia
title_short A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
title_full A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
title_fullStr A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
title_full_unstemmed A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
title_sort A Rare Case of Spontaneous Remission and Relapse of a Primary Central Nervous System Lymphoma
author Ramos, R
author_facet Ramos, R
Fernandes, JS
Almeida, M
Almeida, R
author_role author
author2 Fernandes, JS
Almeida, M
Almeida, R
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Hospital de Braga
dc.contributor.author.fl_str_mv Ramos, R
Fernandes, JS
Almeida, M
Almeida, R
dc.subject.por.fl_str_mv Linfoma/quimioterapia
Linfoma/radioterapia
Neoplasias do Sistema Nervoso Central/quimioterapia
Neoplasias do Sistema Nervoso Central/radioterapia
topic Linfoma/quimioterapia
Linfoma/radioterapia
Neoplasias do Sistema Nervoso Central/quimioterapia
Neoplasias do Sistema Nervoso Central/radioterapia
description Primary central nervous system lymphoma remission after steroid treatment is a well-known phenomenon, but remission without any type of treatment is extremely rare. We present a rare case of spontaneous remission of a diffuse large B-cell lymphoma of the central nervous system as well as its subsequent reappearance in another location. The atypical presentation misled the neurosurgeons and neurologists, delaying diagnosis and treatment. The patient underwent brain biopsy after the relapse and started radiotherapy and chemotherapy with cytarabine + methotrexate + rituximab. As of 32 months after the diagnosis, the patient remained asymptomatic, with no focal neurological deficits and the disease in complete remission. A PubMed search of the literature up to June 2017 regarding spontaneous remission central nervous system lymphoma was also carried out.
publishDate 2018
dc.date.none.fl_str_mv 2018-12-28T00:00:00Z
2018-12-28T00:00:00Z
2019-03-01T14:13:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.23/1317
url http://hdl.handle.net/10400.23/1317
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Med Port. 2018 Dec 28;31(12):777-783.
10.20344/amp.10198
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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