Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and Their Treatment

Detalhes bibliográficos
Autor(a) principal: Garrido, Pedro Miguel
Data de Publicação: 2018
Outros Autores: Borges-Costa, João
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: https://doi.org/10.29021/spdv.76.1.847
Resumo: Genital herpes is a sexually transmitted infection with high global prevalence. Atypical clinical presentations of herpetic infection are rare but are becoming increasingly frequent due to the growing number of immunosuppressed patients. Therapy is challenging, with a longer treatment duration being frequently needed and an important resistance rate to the common anti-viral agents. Foscarnet and cidofovir are effective alternatives. In this article we review three atypical cutaneous presentations of herpetic infection, selected by their relevance in clinical practice: hypertrophic lesions, chronic ulcers and herpetic folliculitis.
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spelling Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and Their TreatmentManifestações Clínicas Atípicas de Infeção Genital pelos Vírus Herpes Simplex e sua Abordagem TerapêuticaAIDS-Related Opportunistic InfectionsAntiviral AgentsHerpes GenitalisHerpes SimplexSexually Transmitted DiseasesViralAntiviraisDoenças Virais Sexualmente TransmissíveisHerpes GenitalHerpes SimplesInfecções Oportunistas Relacionadas com a SIDAGenital herpes is a sexually transmitted infection with high global prevalence. Atypical clinical presentations of herpetic infection are rare but are becoming increasingly frequent due to the growing number of immunosuppressed patients. Therapy is challenging, with a longer treatment duration being frequently needed and an important resistance rate to the common anti-viral agents. Foscarnet and cidofovir are effective alternatives. In this article we review three atypical cutaneous presentations of herpetic infection, selected by their relevance in clinical practice: hypertrophic lesions, chronic ulcers and herpetic folliculitis.O herpes genital é uma doença sexualmente transmissível com elevada prevalência. As apresentações clínicas atípicas da infeção herpética são raras, mas a sua prevalência aumentou, em relação com o crescente número de indivíduos imunossuprimidos. A terapêutica destas condições é difícil, requerendo maior tempo de tratamento e estando associada a uma importante taxa de resistência aos fármacos anti-virais comumente utilizados. Como alternativas eficazes, salientam-se os anti-virais foscarnet e cidofovir. Neste artigo são abordadas três formas de apresentação cutânea atípica de infeção herpética, selecionadas pela sua relevância na prática clínica: lesões hipertróficas, úlceras crónicas e foliculite herpética.Sociedade Portuguesa de Dermatologia e Venereologia2018-04-05T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.76.1.847oai:ojs.revista.spdv.com.pt:article/847Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 1 (2018): Janeiro - Março; 65-70Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 1 (2018): Janeiro - Março; 65-702182-24092182-2395reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/847https://doi.org/10.29021/spdv.76.1.847https://revista.spdv.com.pt/index.php/spdv/article/view/847/549Garrido, Pedro MiguelBorges-Costa, Joãoinfo:eu-repo/semantics/openAccess2022-10-06T12:35:05Zoai:ojs.revista.spdv.com.pt:article/847Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T10:31:19.032090Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and Their Treatment
Manifestações Clínicas Atípicas de Infeção Genital pelos Vírus Herpes Simplex e sua Abordagem Terapêutica
title Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and Their Treatment
spellingShingle Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and Their Treatment
Garrido, Pedro Miguel
AIDS-Related Opportunistic Infections
Antiviral Agents
Herpes Genitalis
Herpes Simplex
Sexually Transmitted Diseases
Viral
Antivirais
Doenças Virais Sexualmente Transmissíveis
Herpes Genital
Herpes Simples
Infecções Oportunistas Relacionadas com a SIDA
title_short Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and Their Treatment
title_full Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and Their Treatment
title_fullStr Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and Their Treatment
title_full_unstemmed Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and Their Treatment
title_sort Atypical Clinical Manifestations of Genital Herpes Simplex Virus Infection and Their Treatment
author Garrido, Pedro Miguel
author_facet Garrido, Pedro Miguel
Borges-Costa, João
author_role author
author2 Borges-Costa, João
author2_role author
dc.contributor.author.fl_str_mv Garrido, Pedro Miguel
Borges-Costa, João
dc.subject.por.fl_str_mv AIDS-Related Opportunistic Infections
Antiviral Agents
Herpes Genitalis
Herpes Simplex
Sexually Transmitted Diseases
Viral
Antivirais
Doenças Virais Sexualmente Transmissíveis
Herpes Genital
Herpes Simples
Infecções Oportunistas Relacionadas com a SIDA
topic AIDS-Related Opportunistic Infections
Antiviral Agents
Herpes Genitalis
Herpes Simplex
Sexually Transmitted Diseases
Viral
Antivirais
Doenças Virais Sexualmente Transmissíveis
Herpes Genital
Herpes Simples
Infecções Oportunistas Relacionadas com a SIDA
description Genital herpes is a sexually transmitted infection with high global prevalence. Atypical clinical presentations of herpetic infection are rare but are becoming increasingly frequent due to the growing number of immunosuppressed patients. Therapy is challenging, with a longer treatment duration being frequently needed and an important resistance rate to the common anti-viral agents. Foscarnet and cidofovir are effective alternatives. In this article we review three atypical cutaneous presentations of herpetic infection, selected by their relevance in clinical practice: hypertrophic lesions, chronic ulcers and herpetic folliculitis.
publishDate 2018
dc.date.none.fl_str_mv 2018-04-05T00:00:00Z
dc.type.driver.fl_str_mv journal article
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.76.1.847
oai:ojs.revista.spdv.com.pt:article/847
url https://doi.org/10.29021/spdv.76.1.847
identifier_str_mv oai:ojs.revista.spdv.com.pt:article/847
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/847
https://doi.org/10.29021/spdv.76.1.847
https://revista.spdv.com.pt/index.php/spdv/article/view/847/549
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 1 (2018): Janeiro - Março; 65-70
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 1 (2018): Janeiro - Março; 65-70
2182-2409
2182-2395
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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