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Benzoxazole derivatives as phototriggers for the release of butyric acid

Bibliographic Details
Main Author: Soares, Ana M. S.
Publication Date: 2014
Other Authors: Costa, Susana P. G., Gonçalves, M. Sameiro T.
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://hdl.handle.net/1822/31946
Summary: In order to evaluate the application of new benzoxazoles and following the previous work regarding benzoxazoles as photoactive groups and using butyric acid as model, in the preparation of carboxylic acid derivatives, butyric ester conjugates were synthesized by reaction with the chloromethylated heterocyclic precursors.1-3 Photocleavage studies of the ester conjugates in methanol/HEPES buffer (80:20) solution at different wavelengths of irradiation (254, 300, 350 and 419 nm) confirmed the quantitative release of the model acid in short irradiation times.
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network_acronym_str RCAP
network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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spelling Benzoxazole derivatives as phototriggers for the release of butyric acidBenzoxazolesPhototriggersButyric acidCoumarinsOxo-benzopyransProdrugsCiências Naturais::Ciências QuímicasIn order to evaluate the application of new benzoxazoles and following the previous work regarding benzoxazoles as photoactive groups and using butyric acid as model, in the preparation of carboxylic acid derivatives, butyric ester conjugates were synthesized by reaction with the chloromethylated heterocyclic precursors.1-3 Photocleavage studies of the ester conjugates in methanol/HEPES buffer (80:20) solution at different wavelengths of irradiation (254, 300, 350 and 419 nm) confirmed the quantitative release of the model acid in short irradiation times.Fundação para a Ciência e a Tecnologia (FCT)MDPIUniversidade do MinhoSoares, Ana M. S.Costa, Susana P. G.Gonçalves, M. Sameiro T.2014-042014-04-01T00:00:00Zconference paperinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/1822/31946eng10.3390/ecsoc-18-a034http://www.sciforum.net/conference/ecsoc-18/paper/2563info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T05:31:41Zoai:repositorium.sdum.uminho.pt:1822/31946Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T15:21:16.122128Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Benzoxazole derivatives as phototriggers for the release of butyric acid
title Benzoxazole derivatives as phototriggers for the release of butyric acid
spellingShingle Benzoxazole derivatives as phototriggers for the release of butyric acid
Soares, Ana M. S.
Benzoxazoles
Phototriggers
Butyric acid
Coumarins
Oxo-benzopyrans
Prodrugs
Ciências Naturais::Ciências Químicas
title_short Benzoxazole derivatives as phototriggers for the release of butyric acid
title_full Benzoxazole derivatives as phototriggers for the release of butyric acid
title_fullStr Benzoxazole derivatives as phototriggers for the release of butyric acid
title_full_unstemmed Benzoxazole derivatives as phototriggers for the release of butyric acid
title_sort Benzoxazole derivatives as phototriggers for the release of butyric acid
author Soares, Ana M. S.
author_facet Soares, Ana M. S.
Costa, Susana P. G.
Gonçalves, M. Sameiro T.
author_role author
author2 Costa, Susana P. G.
Gonçalves, M. Sameiro T.
author2_role author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Soares, Ana M. S.
Costa, Susana P. G.
Gonçalves, M. Sameiro T.
dc.subject.por.fl_str_mv Benzoxazoles
Phototriggers
Butyric acid
Coumarins
Oxo-benzopyrans
Prodrugs
Ciências Naturais::Ciências Químicas
topic Benzoxazoles
Phototriggers
Butyric acid
Coumarins
Oxo-benzopyrans
Prodrugs
Ciências Naturais::Ciências Químicas
description In order to evaluate the application of new benzoxazoles and following the previous work regarding benzoxazoles as photoactive groups and using butyric acid as model, in the preparation of carboxylic acid derivatives, butyric ester conjugates were synthesized by reaction with the chloromethylated heterocyclic precursors.1-3 Photocleavage studies of the ester conjugates in methanol/HEPES buffer (80:20) solution at different wavelengths of irradiation (254, 300, 350 and 419 nm) confirmed the quantitative release of the model acid in short irradiation times.
publishDate 2014
dc.date.none.fl_str_mv 2014-04
2014-04-01T00:00:00Z
dc.type.driver.fl_str_mv conference paper
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/31946
url https://hdl.handle.net/1822/31946
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.3390/ecsoc-18-a034
http://www.sciforum.net/conference/ecsoc-18/paper/2563
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833595263334219776

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