Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studies

Bibliographic Details
Main Author: Melo, Ryan
Publication Date: 2022
Other Authors: Machado, Carolina, Caldeira, Daniel, Alves, Mariana, Lopes, Alice, Serrano, Maria, Fernandes E Fernandes, Ruy, Pedro, Luís M
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10451/50786
Summary: © 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/
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spelling Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studiesAortic dissectionIncidenceMeta-analysisOut-of-hospital cardiac arrestSystematic review© 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/Objectives: Acute Aortic dissection (AAD) may present as out-of-hospital cardiac arrest (OHCA). However, the incidence of this presentation is not well known. Our aim was to perform a systematic review and meta-analysis of all observational studies reporting on the incidence of AAD in patients with OHCA. Methods: We searched MEDLINE, CENTRAL, PsycInfo, Web of Science Core Collection and OpenGrey databases from inception to March-2021, for observational studies reporting on the incidence of AAD in patients with OHCA. Data was pooled using a random-effects model of proportions. The primary outcome was the incidence of AAD in OHCA patients. Secondary outcomes were the incidence of type A aortic dissections (TAAD) and type B aortic dissections (TBAD) in OHCA patients, overall mortality following AAD-OHCA and risk of death in AAD-OHCA patients compared to risk of death of non-AAD-OHCA patients. Results: Fourteen studies were included. The pooled calculated incidence of OHCA due to AAD was 4.39% (95 %CI: 2.55; 6.8). Incidence of OHCA due to TAAD was 7.18% (95 %CI: 5.61; 8.93) and incidence of OHCA due to TBAD was 0.47% (95 %CI: 0.18; 0.85). Overall mortality following OHCA due to AAD was 100% (95 %CI: 97.62; 100). The risk of death in AAD-OHCA patients compared with non-AAD-OHCA patients was 1.10 (95 %CI: 0.94; 1.30). Conclusion: AAD as a cause of OHCA is more frequent than previously thought. Prognosis is dire, as it is invariably lethal. These findings should lead to a higher awareness of AAD when approaching a patient with OHCA and to future studies on this matter.ElsevierRepositório da Universidade de LisboaMelo, RyanMachado, CarolinaCaldeira, DanielAlves, MarianaLopes, AliceSerrano, MariaFernandes E Fernandes, RuyPedro, Luís M2022-01-12T15:08:07Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/50786engInt J Cardiol Heart Vasc. 2021 Dec 23;38:1009342352-906710.1016/j.ijcha.2021.100934info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T14:40:10Zoai:repositorio.ulisboa.pt:10451/50786Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:20:56.622915Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studies
title Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studies
spellingShingle Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studies
Melo, Ryan
Aortic dissection
Incidence
Meta-analysis
Out-of-hospital cardiac arrest
Systematic review
title_short Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studies
title_full Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studies
title_fullStr Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studies
title_full_unstemmed Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studies
title_sort Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studies
author Melo, Ryan
author_facet Melo, Ryan
Machado, Carolina
Caldeira, Daniel
Alves, Mariana
Lopes, Alice
Serrano, Maria
Fernandes E Fernandes, Ruy
Pedro, Luís M
author_role author
author2 Machado, Carolina
Caldeira, Daniel
Alves, Mariana
Lopes, Alice
Serrano, Maria
Fernandes E Fernandes, Ruy
Pedro, Luís M
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Melo, Ryan
Machado, Carolina
Caldeira, Daniel
Alves, Mariana
Lopes, Alice
Serrano, Maria
Fernandes E Fernandes, Ruy
Pedro, Luís M
dc.subject.por.fl_str_mv Aortic dissection
Incidence
Meta-analysis
Out-of-hospital cardiac arrest
Systematic review
topic Aortic dissection
Incidence
Meta-analysis
Out-of-hospital cardiac arrest
Systematic review
description © 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/
publishDate 2022
dc.date.none.fl_str_mv 2022-01-12T15:08:07Z
2022
2022-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/50786
url http://hdl.handle.net/10451/50786
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Cardiol Heart Vasc. 2021 Dec 23;38:100934
2352-9067
10.1016/j.ijcha.2021.100934
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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