Adherence and biofilm formation of non-Candida albicans Candida species

Bibliographic Details
Main Author: Silva, Sónia Carina
Publication Date: 2011
Other Authors: Negri, M., Henriques, Mariana, Williams, David, Oliveira, Rosário, Azeredo, Joana
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://hdl.handle.net/1822/16774
Summary: Most cases of candidosis have been attributed to Candida albicans, but recently non-Candida albicans Candida species have been identified as frequent human pathogens. Candida pathogenicity has been attributed to several factors, including adhesion to medical devices and/or host cells, biofilm formation, and secretion of hydrolytic enzymes (proteases, phospholipases, and haemolysins). Although ‘new’ Candida species are emerging, there is still a lack of information about their pathogenicity. This review discusses recent advances in our knowledge of C. glabrata, C. parapsilosis, and C. tropicalis virulence factors, specifically those of adhesion and biofilm formation, which are key components in Candida pathogenicity.
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spelling Adherence and biofilm formation of non-Candida albicans Candida speciesScience & TechnologyMost cases of candidosis have been attributed to Candida albicans, but recently non-Candida albicans Candida species have been identified as frequent human pathogens. Candida pathogenicity has been attributed to several factors, including adhesion to medical devices and/or host cells, biofilm formation, and secretion of hydrolytic enzymes (proteases, phospholipases, and haemolysins). Although ‘new’ Candida species are emerging, there is still a lack of information about their pathogenicity. This review discusses recent advances in our knowledge of C. glabrata, C. parapsilosis, and C. tropicalis virulence factors, specifically those of adhesion and biofilm formation, which are key components in Candida pathogenicity.This work was supported by the Fundacao para Ciencia e Tecnologia (FCT), Portugal (grant SFRH/BD/28341/2006 to S.S.). and the Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES), Brazil (grant BEX-4642/06-6 to M.N.).ElsevierUniversidade do MinhoSilva, Sónia CarinaNegri, M.Henriques, MarianaWilliams, DavidOliveira, RosárioAzeredo, Joana20112011-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/16774eng0966-842X10.1016/j.tim.2011.02.00321411325http://www.sciencedirect.com/info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-04-12T04:28:22Zoai:repositorium.sdum.uminho.pt:1822/16774Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T15:13:07.782687Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Adherence and biofilm formation of non-Candida albicans Candida species
title Adherence and biofilm formation of non-Candida albicans Candida species
spellingShingle Adherence and biofilm formation of non-Candida albicans Candida species
Silva, Sónia Carina
Science & Technology
title_short Adherence and biofilm formation of non-Candida albicans Candida species
title_full Adherence and biofilm formation of non-Candida albicans Candida species
title_fullStr Adherence and biofilm formation of non-Candida albicans Candida species
title_full_unstemmed Adherence and biofilm formation of non-Candida albicans Candida species
title_sort Adherence and biofilm formation of non-Candida albicans Candida species
author Silva, Sónia Carina
author_facet Silva, Sónia Carina
Negri, M.
Henriques, Mariana
Williams, David
Oliveira, Rosário
Azeredo, Joana
author_role author
author2 Negri, M.
Henriques, Mariana
Williams, David
Oliveira, Rosário
Azeredo, Joana
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Silva, Sónia Carina
Negri, M.
Henriques, Mariana
Williams, David
Oliveira, Rosário
Azeredo, Joana
dc.subject.por.fl_str_mv Science & Technology
topic Science & Technology
description Most cases of candidosis have been attributed to Candida albicans, but recently non-Candida albicans Candida species have been identified as frequent human pathogens. Candida pathogenicity has been attributed to several factors, including adhesion to medical devices and/or host cells, biofilm formation, and secretion of hydrolytic enzymes (proteases, phospholipases, and haemolysins). Although ‘new’ Candida species are emerging, there is still a lack of information about their pathogenicity. This review discusses recent advances in our knowledge of C. glabrata, C. parapsilosis, and C. tropicalis virulence factors, specifically those of adhesion and biofilm formation, which are key components in Candida pathogenicity.
publishDate 2011
dc.date.none.fl_str_mv 2011
2011-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/16774
url https://hdl.handle.net/1822/16774
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0966-842X
10.1016/j.tim.2011.02.003
21411325
http://www.sciencedirect.com/
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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instacron_str RCAAP
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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