Injectable composite systems based on microparticles in hydrogels for bioactive cargo controlled delivery

Bibliographic Details
Main Author: Carrêlo, Henrique
Publication Date: 2021
Other Authors: Soares, Paula I. P., Borges, João Paulo, Cidade, Maria Teresa
Format: Other
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/131640
Summary: PTDC/CTMCTM/30623/2017 CEECIND.03189.2020
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network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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spelling Injectable composite systems based on microparticles in hydrogels for bioactive cargo controlled deliveryBioactive cargoBiomedical applicationsDrug delivery systemsHydrogelsMicroparticlesBioengineeringBiomaterialsOrganic ChemistryPolymers and PlasticsPTDC/CTMCTM/30623/2017 CEECIND.03189.2020Engineering drug delivery systems (DDS) aim to release bioactive cargo to a specific site within the human body safely and efficiently. Hydrogels have been used as delivery matrices in different studies due to their biocompatibility, biodegradability, and versatility in biomedical purposes. Microparticles have also been used as drug delivery systems for similar reasons. The combination of microparticles and hydrogels in a composite system has been the topic of many research works. These composite systems can be injected in loco as DDS. The hydrogel will serve as a barrier to protect the particles and retard the release of any bioactive cargo within the particles. Additionally, these systems allow different release profiles, where different loads can be released sequentially, thus allowing a synergistic treatment. The reported advantages from several studies of these systems can be of great use in biomedicine for the development of more effective DDS. This review will focus on in situ injectable microparticles in hydrogel composite DDS for biomedical purposes, where a compilation of different studies will be analysed and reported herein.CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DCM - Departamento de Ciência dos MateriaisRUNCarrêlo, HenriqueSoares, Paula I. P.Borges, João PauloCidade, Maria Teresa2022-01-27T03:24:22Z2021-09-182021-09-18T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttp://hdl.handle.net/10362/131640eng2310-2861PURE: 34089231https://doi.org/10.3390/gels7030147info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T17:58:40Zoai:run.unl.pt:10362/131640Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:29:38.562571Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Injectable composite systems based on microparticles in hydrogels for bioactive cargo controlled delivery
title Injectable composite systems based on microparticles in hydrogels for bioactive cargo controlled delivery
spellingShingle Injectable composite systems based on microparticles in hydrogels for bioactive cargo controlled delivery
Carrêlo, Henrique
Bioactive cargo
Biomedical applications
Drug delivery systems
Hydrogels
Microparticles
Bioengineering
Biomaterials
Organic Chemistry
Polymers and Plastics
title_short Injectable composite systems based on microparticles in hydrogels for bioactive cargo controlled delivery
title_full Injectable composite systems based on microparticles in hydrogels for bioactive cargo controlled delivery
title_fullStr Injectable composite systems based on microparticles in hydrogels for bioactive cargo controlled delivery
title_full_unstemmed Injectable composite systems based on microparticles in hydrogels for bioactive cargo controlled delivery
title_sort Injectable composite systems based on microparticles in hydrogels for bioactive cargo controlled delivery
author Carrêlo, Henrique
author_facet Carrêlo, Henrique
Soares, Paula I. P.
Borges, João Paulo
Cidade, Maria Teresa
author_role author
author2 Soares, Paula I. P.
Borges, João Paulo
Cidade, Maria Teresa
author2_role author
author
author
dc.contributor.none.fl_str_mv CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
DCM - Departamento de Ciência dos Materiais
RUN
dc.contributor.author.fl_str_mv Carrêlo, Henrique
Soares, Paula I. P.
Borges, João Paulo
Cidade, Maria Teresa
dc.subject.por.fl_str_mv Bioactive cargo
Biomedical applications
Drug delivery systems
Hydrogels
Microparticles
Bioengineering
Biomaterials
Organic Chemistry
Polymers and Plastics
topic Bioactive cargo
Biomedical applications
Drug delivery systems
Hydrogels
Microparticles
Bioengineering
Biomaterials
Organic Chemistry
Polymers and Plastics
description PTDC/CTMCTM/30623/2017 CEECIND.03189.2020
publishDate 2021
dc.date.none.fl_str_mv 2021-09-18
2021-09-18T00:00:00Z
2022-01-27T03:24:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/other
format other
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/131640
url http://hdl.handle.net/10362/131640
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2310-2861
PURE: 34089231
https://doi.org/10.3390/gels7030147
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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