Cervical lymph node schwannoma : an unexpected diagnosis

Bibliographic Details
Main Author: Silvestre, Catarina Falcão
Publication Date: 2019
Other Authors: Almeida-Tavares, Joana, López-Presa, Dolores, Santos, Vanessa Rebelo dos, Rocha, José, Bugalho, Maria João
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10451/48998
Summary: © The Author(s) 2019. Sage. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
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spelling Cervical lymph node schwannoma : an unexpected diagnosisSchwannomaIntranodalLymph nodeNeurilemmomaSpindle cells© The Author(s) 2019. Sage. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).Introduction: Schwannomas-Schwann cells-originating tumors-may develop in many locations. However, primary schwannomas arising within lymph nodes are extremely rare, with only a few cases described to this date in the English literature. For the intranodal location, most of the cases are described in the abdominal cavity. In these cases, clinicians may consider and check for familial disorders, such as neurofibromatosis type 2 (NF2) and schwannomatosis also called neurofibromatosis type 3. Schwannomas are benign neoplasms. Histologically, differential diagnosis for spindle-cell lesions in lymph nodes is important and must be done carefully, mainly because they may be attributable to metastatic disease. We report a case of a primary schwannoma arising in a cervical lymph node. Background: Primary schwannomas arising within lymph nodes are extremely rare, with only a few cases reported. Since they are benign neoplasms, the differential diagnosis with other intranodal spindle cell lesions, mostly malignant, is important. Methods: An asymptomatic 69-year-old woman, previously submitted to left hemithyroidectomy for a benign folicular nodule, underwent thyroidectomy totalization following the identification of a large thyroid nodule in routine evaluation. Results: Gross and microscopic examination and ancillary studies were consistent with the diagnosis of intranodal schwannoma. The patient had acquired bilateral hypoacusia. Therefore, type 2 neurofibromatosis was considered and vestibular schwannomas ruled out. Conclusion: Herein, we present the second case of a primary schwannoma in a cervical lymph node reported so far. The relevance of the differential diagnosis is highlighted.SAGE PublishingRepositório da Universidade de LisboaSilvestre, Catarina FalcãoAlmeida-Tavares, JoanaLópez-Presa, DoloresSantos, Vanessa Rebelo dosRocha, JoséBugalho, Maria João2021-07-19T13:20:46Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/48998engClin Pathol. 2019 Feb 27;1210.1177/2632010X198292392632-010Xinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T14:35:25Zoai:repositorio.ulisboa.pt:10451/48998Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:16:29.867412Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Cervical lymph node schwannoma : an unexpected diagnosis
title Cervical lymph node schwannoma : an unexpected diagnosis
spellingShingle Cervical lymph node schwannoma : an unexpected diagnosis
Silvestre, Catarina Falcão
Schwannoma
Intranodal
Lymph node
Neurilemmoma
Spindle cells
title_short Cervical lymph node schwannoma : an unexpected diagnosis
title_full Cervical lymph node schwannoma : an unexpected diagnosis
title_fullStr Cervical lymph node schwannoma : an unexpected diagnosis
title_full_unstemmed Cervical lymph node schwannoma : an unexpected diagnosis
title_sort Cervical lymph node schwannoma : an unexpected diagnosis
author Silvestre, Catarina Falcão
author_facet Silvestre, Catarina Falcão
Almeida-Tavares, Joana
López-Presa, Dolores
Santos, Vanessa Rebelo dos
Rocha, José
Bugalho, Maria João
author_role author
author2 Almeida-Tavares, Joana
López-Presa, Dolores
Santos, Vanessa Rebelo dos
Rocha, José
Bugalho, Maria João
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Silvestre, Catarina Falcão
Almeida-Tavares, Joana
López-Presa, Dolores
Santos, Vanessa Rebelo dos
Rocha, José
Bugalho, Maria João
dc.subject.por.fl_str_mv Schwannoma
Intranodal
Lymph node
Neurilemmoma
Spindle cells
topic Schwannoma
Intranodal
Lymph node
Neurilemmoma
Spindle cells
description © The Author(s) 2019. Sage. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
2021-07-19T13:20:46Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/48998
url http://hdl.handle.net/10451/48998
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Clin Pathol. 2019 Feb 27;12
10.1177/2632010X19829239
2632-010X
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv SAGE Publishing
publisher.none.fl_str_mv SAGE Publishing
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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