Development of a method based on HPLC-DAD for the detection and quantification of glutamate and gamma-aminobutyric acid

Bibliographic Details
Main Author: Machado, Patrícia
Publication Date: 2018
Other Authors: Teixeira, Dulce, Vieira, Mónica, Prudêncio, Cristina
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.22/25660
Summary: With the increasing incidence of neurodegenerative diseases, the need arose to study several molecules that may be useful to the study of new therapies and to treat the symptoms that come with these diseases, as is the case of depression. GABA and glutamate have a very important role in the homeostasis of the organism and molecules of interest and potential from the point of view of diagnosis are revealed. HPLC is a method that allows the detection and quantification of various analytes in different biological matrices, allowing rapid results with high precision, sensitivity and specificity.
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spelling Development of a method based on HPLC-DAD for the detection and quantification of glutamate and gamma-aminobutyric acidNeurodegenerative diseasesDepressionGABAGlutamateHPLC-DADWith the increasing incidence of neurodegenerative diseases, the need arose to study several molecules that may be useful to the study of new therapies and to treat the symptoms that come with these diseases, as is the case of depression. GABA and glutamate have a very important role in the homeostasis of the organism and molecules of interest and potential from the point of view of diagnosis are revealed. HPLC is a method that allows the detection and quantification of various analytes in different biological matrices, allowing rapid results with high precision, sensitivity and specificity.Escola Superior de Saúde P.PortoREPOSITÓRIO P.PORTOMachado, PatríciaTeixeira, DulceVieira, MónicaPrudêncio, Cristina2024-06-14T13:23:41Z2018-05-182018-05-18T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.22/25660eng978-989-20-8533-3info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-07T10:01:12Zoai:recipp.ipp.pt:10400.22/25660Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:25:57.108736Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Development of a method based on HPLC-DAD for the detection and quantification of glutamate and gamma-aminobutyric acid
title Development of a method based on HPLC-DAD for the detection and quantification of glutamate and gamma-aminobutyric acid
spellingShingle Development of a method based on HPLC-DAD for the detection and quantification of glutamate and gamma-aminobutyric acid
Machado, Patrícia
Neurodegenerative diseases
Depression
GABA
Glutamate
HPLC-DAD
title_short Development of a method based on HPLC-DAD for the detection and quantification of glutamate and gamma-aminobutyric acid
title_full Development of a method based on HPLC-DAD for the detection and quantification of glutamate and gamma-aminobutyric acid
title_fullStr Development of a method based on HPLC-DAD for the detection and quantification of glutamate and gamma-aminobutyric acid
title_full_unstemmed Development of a method based on HPLC-DAD for the detection and quantification of glutamate and gamma-aminobutyric acid
title_sort Development of a method based on HPLC-DAD for the detection and quantification of glutamate and gamma-aminobutyric acid
author Machado, Patrícia
author_facet Machado, Patrícia
Teixeira, Dulce
Vieira, Mónica
Prudêncio, Cristina
author_role author
author2 Teixeira, Dulce
Vieira, Mónica
Prudêncio, Cristina
author2_role author
author
author
dc.contributor.none.fl_str_mv REPOSITÓRIO P.PORTO
dc.contributor.author.fl_str_mv Machado, Patrícia
Teixeira, Dulce
Vieira, Mónica
Prudêncio, Cristina
dc.subject.por.fl_str_mv Neurodegenerative diseases
Depression
GABA
Glutamate
HPLC-DAD
topic Neurodegenerative diseases
Depression
GABA
Glutamate
HPLC-DAD
description With the increasing incidence of neurodegenerative diseases, the need arose to study several molecules that may be useful to the study of new therapies and to treat the symptoms that come with these diseases, as is the case of depression. GABA and glutamate have a very important role in the homeostasis of the organism and molecules of interest and potential from the point of view of diagnosis are revealed. HPLC is a method that allows the detection and quantification of various analytes in different biological matrices, allowing rapid results with high precision, sensitivity and specificity.
publishDate 2018
dc.date.none.fl_str_mv 2018-05-18
2018-05-18T00:00:00Z
2024-06-14T13:23:41Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/25660
url http://hdl.handle.net/10400.22/25660
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 978-989-20-8533-3
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Escola Superior de Saúde P.Porto
publisher.none.fl_str_mv Escola Superior de Saúde P.Porto
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833600533042036736

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