Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera

Detalhes bibliográficos
Autor(a) principal: Marslin, Gregory
Data de Publicação: 2015
Outros Autores: Selvakesavan, Rajendran K., Franklin, Gregory, Sarmento, Bruno, Dias, Alberto Carlos Pires
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: https://hdl.handle.net/1822/51316
Resumo: We report on the antimicrobial activity of a cream formulation of silver nanoparticles (AgNPs), biosynthesized using Withania somnifera extract. Aqueous extracts of leaves promoted efficient green synthesis of AgNPs compared to fruits and root extracts of W. somnifera. Biosynthesized AgNPs were characterized for their size and shape by physical-chemical techniques such as UV-visible spectroscopy, laser Doppler anemometry, transmission electron microscopy, scanning electron microscopy, atomic force microscopy, X-ray diffraction, and X-ray energy dispersive spectroscopy. After confirming the antimicrobial potential of AgNPs, they were incorporated into a cream. Cream formulations of AgNPs and AgNO3 were prepared and compared for their antimicrobial activity against human pathogens (Staphylococcus aureus, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Candida albicans) and a plant pathogen (Agrobacterium tumefaciens). Our results show that AgNP creams possess significantly higher antimicrobial activity against the tested organisms.
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spelling Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somniferaWithania somniferaGreen synthesisSilver nanoparticles creamAntimicrobial activityCiências Agrárias::Biotecnologia Agrária e AlimentarScience & TechnologyWe report on the antimicrobial activity of a cream formulation of silver nanoparticles (AgNPs), biosynthesized using Withania somnifera extract. Aqueous extracts of leaves promoted efficient green synthesis of AgNPs compared to fruits and root extracts of W. somnifera. Biosynthesized AgNPs were characterized for their size and shape by physical-chemical techniques such as UV-visible spectroscopy, laser Doppler anemometry, transmission electron microscopy, scanning electron microscopy, atomic force microscopy, X-ray diffraction, and X-ray energy dispersive spectroscopy. After confirming the antimicrobial potential of AgNPs, they were incorporated into a cream. Cream formulations of AgNPs and AgNO3 were prepared and compared for their antimicrobial activity against human pathogens (Staphylococcus aureus, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Candida albicans) and a plant pathogen (Agrobacterium tumefaciens). Our results show that AgNP creams possess significantly higher antimicrobial activity against the tested organisms.This work was supported by Fundacao para a Ciencia e Tecnologia (FCT), projects (PTDC/AGR-ALI/105169/2008 and PTDC/AGR-GPL/119211/2010). Gregory Marslin is supported by a FCT PhD fellowship (SFRH/BD/72809/2010).info:eu-repo/semantics/publishedVersionDove Medical PressUniversidade do MinhoMarslin, GregorySelvakesavan, Rajendran K.Franklin, GregorySarmento, BrunoDias, Alberto Carlos Pires2015-01-012015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/51316engMarslin, G., Selvakesavan, R. K., Franklin, G., Sarmento, B., & Dias, A. C. (2015). Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera. International journal of nanomedicine, 10, 5955.1178-20131178-201310.2147/IJN.S8127126445537https://www.dovepress.com/antimicrobial-activity-of-cream-incorporated-with-silver-nanoparticles-peer-reviewed-article-IJNinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-10-26T01:23:14Zoai:repositorium.sdum.uminho.pt:1822/51316Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T15:27:14.199343Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera
title Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera
spellingShingle Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera
Marslin, Gregory
Withania somnifera
Green synthesis
Silver nanoparticles cream
Antimicrobial activity
Ciências Agrárias::Biotecnologia Agrária e Alimentar
Science & Technology
title_short Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera
title_full Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera
title_fullStr Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera
title_full_unstemmed Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera
title_sort Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera
author Marslin, Gregory
author_facet Marslin, Gregory
Selvakesavan, Rajendran K.
Franklin, Gregory
Sarmento, Bruno
Dias, Alberto Carlos Pires
author_role author
author2 Selvakesavan, Rajendran K.
Franklin, Gregory
Sarmento, Bruno
Dias, Alberto Carlos Pires
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Marslin, Gregory
Selvakesavan, Rajendran K.
Franklin, Gregory
Sarmento, Bruno
Dias, Alberto Carlos Pires
dc.subject.por.fl_str_mv Withania somnifera
Green synthesis
Silver nanoparticles cream
Antimicrobial activity
Ciências Agrárias::Biotecnologia Agrária e Alimentar
Science & Technology
topic Withania somnifera
Green synthesis
Silver nanoparticles cream
Antimicrobial activity
Ciências Agrárias::Biotecnologia Agrária e Alimentar
Science & Technology
description We report on the antimicrobial activity of a cream formulation of silver nanoparticles (AgNPs), biosynthesized using Withania somnifera extract. Aqueous extracts of leaves promoted efficient green synthesis of AgNPs compared to fruits and root extracts of W. somnifera. Biosynthesized AgNPs were characterized for their size and shape by physical-chemical techniques such as UV-visible spectroscopy, laser Doppler anemometry, transmission electron microscopy, scanning electron microscopy, atomic force microscopy, X-ray diffraction, and X-ray energy dispersive spectroscopy. After confirming the antimicrobial potential of AgNPs, they were incorporated into a cream. Cream formulations of AgNPs and AgNO3 were prepared and compared for their antimicrobial activity against human pathogens (Staphylococcus aureus, Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and Candida albicans) and a plant pathogen (Agrobacterium tumefaciens). Our results show that AgNP creams possess significantly higher antimicrobial activity against the tested organisms.
publishDate 2015
dc.date.none.fl_str_mv 2015-01-01
2015-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/51316
url https://hdl.handle.net/1822/51316
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Marslin, G., Selvakesavan, R. K., Franklin, G., Sarmento, B., & Dias, A. C. (2015). Antimicrobial activity of cream incorporated with silver nanoparticles biosynthesized from Withania somnifera. International journal of nanomedicine, 10, 5955.
1178-2013
1178-2013
10.2147/IJN.S81271
26445537
https://www.dovepress.com/antimicrobial-activity-of-cream-incorporated-with-silver-nanoparticles-peer-reviewed-article-IJN
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Dove Medical Press
publisher.none.fl_str_mv Dove Medical Press
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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