Insights on the thermal aging of acrylic reline resins

Detalhes bibliográficos
Autor(a) principal: Pacheco, Filipe Gaudêncio
Data de Publicação: 2016
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: http://hdl.handle.net/10451/26149
Resumo: Tese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2016
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spelling Insights on the thermal aging of acrylic reline resinsMateriais dentáriosResinas acrílicasClorexidinaTeses de mestrado - 2016Domínio/Área Científica::Ciências Médicas::Medicina ClínicaTese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2016The use of controlled-release agents has being studied as therapeutic alternatives for the treatment of denture stomatitis. The main purpose of this study was to evaluate mass variation color stability and drug release of acrylic reline resins loaded with chlorhexidine after thermal aging. Three different materials were evaluated in the present study, Kooliner, Ufi Gel Hard and Probase Cold. For each, one control group and four experimental groups with chlorhexidine (2.5%, 5%, 7.5% and 10% (w/w)) were produced. A total of 45 cylindershaped specimens were evaluated. Mass was calculated using a precision scale and color was evaluated using a spectrophotometer. These measurements were made before and after a thermocycling aging procedure of 1000 cycles of thermal fluctuations between 5ºC and 55ºC (20 seconds each bath). After that, the cylinders were stored individually in graduated falcon tubes and covered with saliva at pH=7. The falcons were then placed into an incubator and, at specific time intervals, an aliquot were collected from each falcon and the same amount of artificial saliva was renovated, in order to simulate the constant salivary renovation. The samples were analyzed by UVspectroscopy and chlorhexidine content was determined. Data were submitted to nonparametric tests according to Mann-Whitney and Kruskall Wallis methods (p<0.05). Results showed that thermocycling caused variationsin mass in all the materials. For Ufigel and Kooliner specimens, chlorhexidine incorporation caused a mass decrease when compared to control. However, clorhexidine incorporation didn’t affect mass variation on Probase Cold. It was also observed that thermocycling caused color variation in all the specimens but chlorhexidine incorporation didn’t affect the color stability. Color variation was higher in Probase Cold followed by Ufi Gel Hard and Kooliner. after thermocycling, it was perceived that only Probase Cold released chlorhexidine whose quantification was superior to 0.6 μg/mL (minimum detectable capacity of the technique used). Overall, results indicate that chlorhexidine delivery systems based on acrylic reline resins are a potential approach in the treatment of denture stomatitis.Neves, Maria Cristina Bettencourt, 1976-Bettencourt, Ana FranciscaRepositório da Universidade de LisboaPacheco, Filipe Gaudêncio2017-01-24T10:55:58Z201620162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10451/26149TID:201289504enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T13:35:06Zoai:repositorio.ulisboa.pt:10451/26149Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T02:48:33.578371Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Insights on the thermal aging of acrylic reline resins
title Insights on the thermal aging of acrylic reline resins
spellingShingle Insights on the thermal aging of acrylic reline resins
Pacheco, Filipe Gaudêncio
Materiais dentários
Resinas acrílicas
Clorexidina
Teses de mestrado - 2016
Domínio/Área Científica::Ciências Médicas::Medicina Clínica
title_short Insights on the thermal aging of acrylic reline resins
title_full Insights on the thermal aging of acrylic reline resins
title_fullStr Insights on the thermal aging of acrylic reline resins
title_full_unstemmed Insights on the thermal aging of acrylic reline resins
title_sort Insights on the thermal aging of acrylic reline resins
author Pacheco, Filipe Gaudêncio
author_facet Pacheco, Filipe Gaudêncio
author_role author
dc.contributor.none.fl_str_mv Neves, Maria Cristina Bettencourt, 1976-
Bettencourt, Ana Francisca
Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Pacheco, Filipe Gaudêncio
dc.subject.por.fl_str_mv Materiais dentários
Resinas acrílicas
Clorexidina
Teses de mestrado - 2016
Domínio/Área Científica::Ciências Médicas::Medicina Clínica
topic Materiais dentários
Resinas acrílicas
Clorexidina
Teses de mestrado - 2016
Domínio/Área Científica::Ciências Médicas::Medicina Clínica
description Tese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2016
publishDate 2016
dc.date.none.fl_str_mv 2016
2016
2016-01-01T00:00:00Z
2017-01-24T10:55:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/26149
TID:201289504
url http://hdl.handle.net/10451/26149
identifier_str_mv TID:201289504
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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repository.mail.fl_str_mv info@rcaap.pt
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