Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates

Bibliographic Details
Main Author: Raposo, Sara
Publication Date: 2010
Other Authors: Azevedo, F., Lima-Costa, Maria Emília
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.1/4792
Summary: Most of animal and plant cell cultures present a non-Newtonian behaviour that has a deep effect on the technological performance of bioreactors, affecting the pattern of mixing, the power input required and on the mass and energy transfer as well. In aerobic cultures, the oxygen mass transfer is still a bottleneck, particularly at industrial scale-up, where the high-cell-density biomass and production of metabolites provoke the increase on the viscosity culture, lowering the production yield and eventually losing economical process viability.
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spelling Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer ratesOxygen transferEmpirical correlationNon-Newtonian fluidsStirred tank reactorMost of animal and plant cell cultures present a non-Newtonian behaviour that has a deep effect on the technological performance of bioreactors, affecting the pattern of mixing, the power input required and on the mass and energy transfer as well. In aerobic cultures, the oxygen mass transfer is still a bottleneck, particularly at industrial scale-up, where the high-cell-density biomass and production of metabolites provoke the increase on the viscosity culture, lowering the production yield and eventually losing economical process viability.ElsevierSapientiaRaposo, SaraAzevedo, F.Lima-Costa, Maria Emília2014-07-22T12:11:06Z20102014-07-22T11:42:09Z2010-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/4792eng0168-1656AUT: SRA01180;10.1016/j.jbiotec.2010.09.509info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-18T17:45:54Zoai:sapientia.ualg.pt:10400.1/4792Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T20:34:46.005825Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
title Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
spellingShingle Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
Raposo, Sara
Oxygen transfer
Empirical correlation
Non-Newtonian fluids
Stirred tank reactor
title_short Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
title_full Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
title_fullStr Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
title_full_unstemmed Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
title_sort Development of an empirical correlation for Newtonian and non-Newtonian fluids in a stirred tank reactor, to predict oxygen mass transfer rates
author Raposo, Sara
author_facet Raposo, Sara
Azevedo, F.
Lima-Costa, Maria Emília
author_role author
author2 Azevedo, F.
Lima-Costa, Maria Emília
author2_role author
author
dc.contributor.none.fl_str_mv Sapientia
dc.contributor.author.fl_str_mv Raposo, Sara
Azevedo, F.
Lima-Costa, Maria Emília
dc.subject.por.fl_str_mv Oxygen transfer
Empirical correlation
Non-Newtonian fluids
Stirred tank reactor
topic Oxygen transfer
Empirical correlation
Non-Newtonian fluids
Stirred tank reactor
description Most of animal and plant cell cultures present a non-Newtonian behaviour that has a deep effect on the technological performance of bioreactors, affecting the pattern of mixing, the power input required and on the mass and energy transfer as well. In aerobic cultures, the oxygen mass transfer is still a bottleneck, particularly at industrial scale-up, where the high-cell-density biomass and production of metabolites provoke the increase on the viscosity culture, lowering the production yield and eventually losing economical process viability.
publishDate 2010
dc.date.none.fl_str_mv 2010
2010-01-01T00:00:00Z
2014-07-22T12:11:06Z
2014-07-22T11:42:09Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.1/4792
url http://hdl.handle.net/10400.1/4792
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0168-1656
AUT: SRA01180;
10.1016/j.jbiotec.2010.09.509
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833598729230221312

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