A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominance

Bibliographic Details
Main Author: Silva, Manuela
Publication Date: 2004
Other Authors: Viegas, Wanda, Lawrence, Richard J., Early, Keith, Pontes, Olga, Chen, Z., Neves, Nuno, Pikaard, Craig S.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.5/2403
Summary: Eukaryotes regulate the effective dosage of their ribosomal RNA (rRNA) genes, expressing fewer than half of the genes at any one time. Likewise, genetic hybrids displaying nucleolar dominance transcribe rRNA genes inherited from one parent but silence the other paraental set.We show that rRNA gene dosage control and nucleolar dominance utilize a common mechanism
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spelling A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominanceeukaryotesrRNAnucleolar dominanceEukaryotes regulate the effective dosage of their ribosomal RNA (rRNA) genes, expressing fewer than half of the genes at any one time. Likewise, genetic hybrids displaying nucleolar dominance transcribe rRNA genes inherited from one parent but silence the other paraental set.We show that rRNA gene dosage control and nucleolar dominance utilize a common mechanismCell PressRepositório da Universidade de LisboaSilva, ManuelaViegas, WandaLawrence, Richard J.Early, KeithPontes, OlgaChen, Z.Neves, NunoPikaard, Craig S.2010-10-26T13:45:01Z20042004-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/2403eng"Molecular Cell". ISSN 1097-2765. 13 (2004) 599-6091097-2765info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T16:00:08Zoai:repositorio.ulisboa.pt:10400.5/2403Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:59:52.803113Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominance
title A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominance
spellingShingle A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominance
Silva, Manuela
eukaryotes
rRNA
nucleolar dominance
title_short A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominance
title_full A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominance
title_fullStr A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominance
title_full_unstemmed A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominance
title_sort A concerted DNA methylation/histone methylation switch regulates rDNA gene dosage control and nucleolar dominance
author Silva, Manuela
author_facet Silva, Manuela
Viegas, Wanda
Lawrence, Richard J.
Early, Keith
Pontes, Olga
Chen, Z.
Neves, Nuno
Pikaard, Craig S.
author_role author
author2 Viegas, Wanda
Lawrence, Richard J.
Early, Keith
Pontes, Olga
Chen, Z.
Neves, Nuno
Pikaard, Craig S.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Silva, Manuela
Viegas, Wanda
Lawrence, Richard J.
Early, Keith
Pontes, Olga
Chen, Z.
Neves, Nuno
Pikaard, Craig S.
dc.subject.por.fl_str_mv eukaryotes
rRNA
nucleolar dominance
topic eukaryotes
rRNA
nucleolar dominance
description Eukaryotes regulate the effective dosage of their ribosomal RNA (rRNA) genes, expressing fewer than half of the genes at any one time. Likewise, genetic hybrids displaying nucleolar dominance transcribe rRNA genes inherited from one parent but silence the other paraental set.We show that rRNA gene dosage control and nucleolar dominance utilize a common mechanism
publishDate 2004
dc.date.none.fl_str_mv 2004
2004-01-01T00:00:00Z
2010-10-26T13:45:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/2403
url http://hdl.handle.net/10400.5/2403
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv "Molecular Cell". ISSN 1097-2765. 13 (2004) 599-609
1097-2765
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Cell Press
publisher.none.fl_str_mv Cell Press
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833601904616144896

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