Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine

Detalhes bibliográficos
Autor(a) principal: Brett, Ana Maria Oliveira
Data de Publicação: 2003
Outros Autores: Silva, Luís A., Farace, Giosi, Vadgama, Pankaj, Brett, Christopher M. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: https://hdl.handle.net/10316/5165
https://doi.org/10.1016/S1567-5394(02)00189-5
Resumo: The oxidation mechanism and adsorption of inosine 5'-monophosphate and hypoxanthine were investigated in solutions of different pH using voltammetric and impedance methods at glassy carbon electrodes. For both compounds, the pH dependence from differential pulse voltammetry showed that the same number of electrons and protons are involved in the rate-determining step of the electrochemical reaction. In the case of hypoxanthine, it was also possible to study the effect of different concentrations. At high concentrations of hypoxanthine, two oxidation peaks were observed, the first due to hypoxanthine oxidation with formation of oligomers and the second due to hypoxanthine oligomer oxidation, both compounds adsorbing strongly. Impedance measurements corroborated the voltammetric results and enabled the study of the adsorption of hypoxanthine on glassy carbon.
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spelling Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthineInosine 5'-monophosphateHypoxanthineElectrochemical adsorptionDifferential pulse voltammetryElectrochemical impedanceDNA-biosensorThe oxidation mechanism and adsorption of inosine 5'-monophosphate and hypoxanthine were investigated in solutions of different pH using voltammetric and impedance methods at glassy carbon electrodes. For both compounds, the pH dependence from differential pulse voltammetry showed that the same number of electrons and protons are involved in the rate-determining step of the electrochemical reaction. In the case of hypoxanthine, it was also possible to study the effect of different concentrations. At high concentrations of hypoxanthine, two oxidation peaks were observed, the first due to hypoxanthine oxidation with formation of oligomers and the second due to hypoxanthine oligomer oxidation, both compounds adsorbing strongly. Impedance measurements corroborated the voltammetric results and enabled the study of the adsorption of hypoxanthine on glassy carbon.http://www.sciencedirect.com/science/article/B6W72-47R9YPB-1/1/a6995627364cc875adcae0c8f04fbcd52003info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleaplication/PDFhttps://hdl.handle.net/10316/5165https://hdl.handle.net/10316/5165https://doi.org/10.1016/S1567-5394(02)00189-5engBioelectrochemistry. 59:1-2 (2003) 49-56Brett, Ana Maria OliveiraSilva, Luís A.Farace, GiosiVadgama, PankajBrett, Christopher M. A.info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2020-11-06T16:59:58Zoai:estudogeral.uc.pt:10316/5165Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T05:23:36.773711Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
title Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
spellingShingle Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
Brett, Ana Maria Oliveira
Inosine 5'-monophosphate
Hypoxanthine
Electrochemical adsorption
Differential pulse voltammetry
Electrochemical impedance
DNA-biosensor
title_short Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
title_full Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
title_fullStr Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
title_full_unstemmed Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
title_sort Voltammetric and impedance studies of inosine-5'-monophosphate and hypoxanthine
author Brett, Ana Maria Oliveira
author_facet Brett, Ana Maria Oliveira
Silva, Luís A.
Farace, Giosi
Vadgama, Pankaj
Brett, Christopher M. A.
author_role author
author2 Silva, Luís A.
Farace, Giosi
Vadgama, Pankaj
Brett, Christopher M. A.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Brett, Ana Maria Oliveira
Silva, Luís A.
Farace, Giosi
Vadgama, Pankaj
Brett, Christopher M. A.
dc.subject.por.fl_str_mv Inosine 5'-monophosphate
Hypoxanthine
Electrochemical adsorption
Differential pulse voltammetry
Electrochemical impedance
DNA-biosensor
topic Inosine 5'-monophosphate
Hypoxanthine
Electrochemical adsorption
Differential pulse voltammetry
Electrochemical impedance
DNA-biosensor
description The oxidation mechanism and adsorption of inosine 5'-monophosphate and hypoxanthine were investigated in solutions of different pH using voltammetric and impedance methods at glassy carbon electrodes. For both compounds, the pH dependence from differential pulse voltammetry showed that the same number of electrons and protons are involved in the rate-determining step of the electrochemical reaction. In the case of hypoxanthine, it was also possible to study the effect of different concentrations. At high concentrations of hypoxanthine, two oxidation peaks were observed, the first due to hypoxanthine oxidation with formation of oligomers and the second due to hypoxanthine oligomer oxidation, both compounds adsorbing strongly. Impedance measurements corroborated the voltammetric results and enabled the study of the adsorption of hypoxanthine on glassy carbon.
publishDate 2003
dc.date.none.fl_str_mv 2003
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/10316/5165
https://hdl.handle.net/10316/5165
https://doi.org/10.1016/S1567-5394(02)00189-5
url https://hdl.handle.net/10316/5165
https://doi.org/10.1016/S1567-5394(02)00189-5
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Bioelectrochemistry. 59:1-2 (2003) 49-56
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv aplication/PDF
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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