Inflammation of BCG Inoculation Site Scar after the First Dose of an Anti-SARS-CoV-2 mRNA Vaccine

Bibliographic Details
Main Author: Barros Rodrigues, João
Publication Date: 2022
Other Authors: Pacheco, Maria, Antunes, Ivan, Sousa, Ricardo
Format: Article
Language: por
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16971
Summary: Inflammatory reactions in the Bacillus Calmette-Guérin (BCG) inoculation scar site have been previously described, in association with viral infections. The inflammation of the scar in association with other vaccines has been described with the flu vaccine and, more recently, after the second dose of mRNA anti-SARS-CoV-2 vaccines (mRNA-1273 e BNT162b2), in two healthcare workers. We present the case of a 27-year-old female, without a relevant past medical history, including no previous SARS-CoV-2 infection, and with inflammation of the BCG scar eight days after the first dose of the mRNA anti-SARS-CoV-2 vaccine. Pharmacovigilance and the notification of adverse events should be encouraged, as a way of warding off hesitation in this process.
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spelling Inflammation of BCG Inoculation Site Scar after the First Dose of an Anti-SARS-CoV-2 mRNA VaccineInflamação na Cicatriz BCG após Primeira Dose de Vacina mRNA Anti-SARS-CoV-2BCG VaccineCicatrixCOVID-19 VaccinesDrug-Related Side Effects and Adverse ReactionsmRNA VaccinesSARS-CoV-2CicatrizEfeito Colateral e Reação Adversa Relacionados a MedicamentosmRNA SARS-CoV-2Vacina BCGVacinas contra COVID-19Vacinas de mRNAInflammatory reactions in the Bacillus Calmette-Guérin (BCG) inoculation scar site have been previously described, in association with viral infections. The inflammation of the scar in association with other vaccines has been described with the flu vaccine and, more recently, after the second dose of mRNA anti-SARS-CoV-2 vaccines (mRNA-1273 e BNT162b2), in two healthcare workers. We present the case of a 27-year-old female, without a relevant past medical history, including no previous SARS-CoV-2 infection, and with inflammation of the BCG scar eight days after the first dose of the mRNA anti-SARS-CoV-2 vaccine. Pharmacovigilance and the notification of adverse events should be encouraged, as a way of warding off hesitation in this process.Reações inflamatórias no local da cicatriz da vacina Bacillus Calmette-Guérin (BCG) foram previamente descritas em relação a infeções virais. A inflamação da cicatriz da BCG em relação à administração de vacinas foi reportada com a vacina da gripe, e, mais recentemente, após a segunda dose das vacinas mRNA anti-SARS-CoV-2 disponíveis (mRNA-1273 e BNT162b2), em dois profissionais de saúde. Aqui apresentamos o caso de uma jovem de 27 anos, sem história pregressa relevante, incluindo infeção por SARS-CoV-2, com inflamação da cicatriz da BCG oito dias após a primeira administração de vacina mRNA anti-SARS-CoV-2. A farmacovigilância e a notificação de reações adversas devem ser incentivadas, de forma a não criar hesitação nesse processo.Ordem dos Médicos2022-09-19info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16971Acta Médica Portuguesa; Vol. 36 No. 7-8 (2023): July-August; 511-514Acta Médica Portuguesa; Vol. 36 N.º 7-8 (2023): Julho-Agosto; 511-5141646-07580870-399Xreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16971https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16971/6756Direitos de Autor (c) 2022 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessBarros Rodrigues, JoãoPacheco, MariaAntunes, IvanSousa, Ricardo2023-07-09T03:00:22Zoai:ojs.www.actamedicaportuguesa.com:article/16971Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T10:42:42.918322Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Inflammation of BCG Inoculation Site Scar after the First Dose of an Anti-SARS-CoV-2 mRNA Vaccine
Inflamação na Cicatriz BCG após Primeira Dose de Vacina mRNA Anti-SARS-CoV-2
title Inflammation of BCG Inoculation Site Scar after the First Dose of an Anti-SARS-CoV-2 mRNA Vaccine
spellingShingle Inflammation of BCG Inoculation Site Scar after the First Dose of an Anti-SARS-CoV-2 mRNA Vaccine
Barros Rodrigues, João
BCG Vaccine
Cicatrix
COVID-19 Vaccines
Drug-Related Side Effects and Adverse Reactions
mRNA Vaccines
SARS-CoV-2
Cicatriz
Efeito Colateral e Reação Adversa Relacionados a Medicamentos
mRNA SARS-CoV-2
Vacina BCG
Vacinas contra COVID-19
Vacinas de mRNA
title_short Inflammation of BCG Inoculation Site Scar after the First Dose of an Anti-SARS-CoV-2 mRNA Vaccine
title_full Inflammation of BCG Inoculation Site Scar after the First Dose of an Anti-SARS-CoV-2 mRNA Vaccine
title_fullStr Inflammation of BCG Inoculation Site Scar after the First Dose of an Anti-SARS-CoV-2 mRNA Vaccine
title_full_unstemmed Inflammation of BCG Inoculation Site Scar after the First Dose of an Anti-SARS-CoV-2 mRNA Vaccine
title_sort Inflammation of BCG Inoculation Site Scar after the First Dose of an Anti-SARS-CoV-2 mRNA Vaccine
author Barros Rodrigues, João
author_facet Barros Rodrigues, João
Pacheco, Maria
Antunes, Ivan
Sousa, Ricardo
author_role author
author2 Pacheco, Maria
Antunes, Ivan
Sousa, Ricardo
author2_role author
author
author
dc.contributor.author.fl_str_mv Barros Rodrigues, João
Pacheco, Maria
Antunes, Ivan
Sousa, Ricardo
dc.subject.por.fl_str_mv BCG Vaccine
Cicatrix
COVID-19 Vaccines
Drug-Related Side Effects and Adverse Reactions
mRNA Vaccines
SARS-CoV-2
Cicatriz
Efeito Colateral e Reação Adversa Relacionados a Medicamentos
mRNA SARS-CoV-2
Vacina BCG
Vacinas contra COVID-19
Vacinas de mRNA
topic BCG Vaccine
Cicatrix
COVID-19 Vaccines
Drug-Related Side Effects and Adverse Reactions
mRNA Vaccines
SARS-CoV-2
Cicatriz
Efeito Colateral e Reação Adversa Relacionados a Medicamentos
mRNA SARS-CoV-2
Vacina BCG
Vacinas contra COVID-19
Vacinas de mRNA
description Inflammatory reactions in the Bacillus Calmette-Guérin (BCG) inoculation scar site have been previously described, in association with viral infections. The inflammation of the scar in association with other vaccines has been described with the flu vaccine and, more recently, after the second dose of mRNA anti-SARS-CoV-2 vaccines (mRNA-1273 e BNT162b2), in two healthcare workers. We present the case of a 27-year-old female, without a relevant past medical history, including no previous SARS-CoV-2 infection, and with inflammation of the BCG scar eight days after the first dose of the mRNA anti-SARS-CoV-2 vaccine. Pharmacovigilance and the notification of adverse events should be encouraged, as a way of warding off hesitation in this process.
publishDate 2022
dc.date.none.fl_str_mv 2022-09-19
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16971
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16971
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16971
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16971/6756
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2022 Acta Médica Portuguesa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2022 Acta Médica Portuguesa
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 36 No. 7-8 (2023): July-August; 511-514
Acta Médica Portuguesa; Vol. 36 N.º 7-8 (2023): Julho-Agosto; 511-514
1646-0758
0870-399X
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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