In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistance

Bibliographic Details
Main Author: Franco, IS
Publication Date: 2024
Format: Master thesis
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/179786
Summary: "BACKGROUND AND AIMS: Although indole-3-propionic acid (IPA) has been shown to exhibit preventive effects against type 2 diabetes (T2D), nothing is known regarding its ability to restore T2D-associated hallmarks. As such, this study aimed to assess the ability of IPA to reverse the metabolic phenotype of insulin-resistant 3T3-L1 adipocytes.(...)"
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network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository_id_str https://opendoar.ac.uk/repository/7160
spelling In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistanceadipocytesglucose uptakehyperinsulinemiainsulin resistancelipolysisindole-3-propionic acid"BACKGROUND AND AIMS: Although indole-3-propionic acid (IPA) has been shown to exhibit preventive effects against type 2 diabetes (T2D), nothing is known regarding its ability to restore T2D-associated hallmarks. As such, this study aimed to assess the ability of IPA to reverse the metabolic phenotype of insulin-resistant 3T3-L1 adipocytes.(...)"Universidade NOVA de Lisboa. Instituto de Tecnologia Química e Biológica António XavierRUNFranco, IS2025-02-25T16:10:12Z2024-02-022024-02-02T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10362/179786TID:203774574enginfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-04-14T01:38:15Zoai:run.unl.pt:10362/179786Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:07:02.771538Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistance
title In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistance
spellingShingle In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistance
Franco, IS
adipocytes
glucose uptake
hyperinsulinemia
insulin resistance
lipolysis
indole-3-propionic acid
title_short In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistance
title_full In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistance
title_fullStr In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistance
title_full_unstemmed In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistance
title_sort In vitro effect of gut microbiota-derived indole-3-propionic acid on insulin resistance
author Franco, IS
author_facet Franco, IS
author_role author
dc.contributor.none.fl_str_mv RUN
dc.contributor.author.fl_str_mv Franco, IS
dc.subject.por.fl_str_mv adipocytes
glucose uptake
hyperinsulinemia
insulin resistance
lipolysis
indole-3-propionic acid
topic adipocytes
glucose uptake
hyperinsulinemia
insulin resistance
lipolysis
indole-3-propionic acid
description "BACKGROUND AND AIMS: Although indole-3-propionic acid (IPA) has been shown to exhibit preventive effects against type 2 diabetes (T2D), nothing is known regarding its ability to restore T2D-associated hallmarks. As such, this study aimed to assess the ability of IPA to reverse the metabolic phenotype of insulin-resistant 3T3-L1 adipocytes.(...)"
publishDate 2024
dc.date.none.fl_str_mv 2024-02-02
2024-02-02T00:00:00Z
2025-02-25T16:10:12Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/179786
TID:203774574
url http://hdl.handle.net/10362/179786
identifier_str_mv TID:203774574
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade NOVA de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier
publisher.none.fl_str_mv Universidade NOVA de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833600403992739840

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