Occupational exposure to bisphenol A (BPA): a reality that still needs to be unveiled

Bibliographic Details
Main Author: Ribeiro, Edna
Publication Date: 2017
Other Authors: Ladeira, Carina, Viegas, Susana
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.5/14143
Summary: Review
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spelling Occupational exposure to bisphenol A (BPA): a reality that still needs to be unveiledbisphenol A (BPA)endocrine disruptorgenotoxicityoccupational exposureexposure assessmenthealth effectsReviewBisphenol A (BPA), 2,2-bis(4-hydroxyphenyl) propane, is one of the most utilized industrial chemicals worldwide, with the ability to interfere with/or mimic estrogenic hormones with associated biological responses. Environmental human exposure to this endocrine disruptor, mostly through oral intake, is considered a generalized phenomenon, particularly in developed countries. However, in the context of occupational exposure, non-dietary exposure sources (e.g., air and contact) cannot be underestimated. Here, we performed a review of the literature on BPA occupational exposure and associated health effects. Relevantly, the authors only identified 19 studies from 2009 to 2017 that demonstrate that occupationally exposed individuals have significantly higher detected BPA levels than environmentally exposed populations and that the detection rate of serum BPA increases in relation to the time of exposure. However, only 12 studies performed in China have correlated potential health effects with detected BPA levels, and shown that BPA-exposed male workers are at greater risk of male sexual dysfunction across all domains of sexual function; also, endocrine disruption, alterations to epigenetic marks (DNA methylation) and epidemiological evidence have shown significant effects on the offspring of parents exposed to BPA during pregnancy. This overview raises awareness of the dramatic and consistent increase in the production and exposure of BPA and creates urgency to assess the actual exposure of workers to this xenoestrogen and to evaluate potential associated adverse health effectsMDPIRepositório da Universidade de LisboaRibeiro, EdnaLadeira, CarinaViegas, Susana2017-10-04T15:12:32Z20172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.5/14143engToxics 2017, 5, 2210.3390/toxics5030022info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T16:11:05Zoai:repositorio.ulisboa.pt:10400.5/14143Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T04:05:08.823280Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Occupational exposure to bisphenol A (BPA): a reality that still needs to be unveiled
title Occupational exposure to bisphenol A (BPA): a reality that still needs to be unveiled
spellingShingle Occupational exposure to bisphenol A (BPA): a reality that still needs to be unveiled
Ribeiro, Edna
bisphenol A (BPA)
endocrine disruptor
genotoxicity
occupational exposure
exposure assessment
health effects
title_short Occupational exposure to bisphenol A (BPA): a reality that still needs to be unveiled
title_full Occupational exposure to bisphenol A (BPA): a reality that still needs to be unveiled
title_fullStr Occupational exposure to bisphenol A (BPA): a reality that still needs to be unveiled
title_full_unstemmed Occupational exposure to bisphenol A (BPA): a reality that still needs to be unveiled
title_sort Occupational exposure to bisphenol A (BPA): a reality that still needs to be unveiled
author Ribeiro, Edna
author_facet Ribeiro, Edna
Ladeira, Carina
Viegas, Susana
author_role author
author2 Ladeira, Carina
Viegas, Susana
author2_role author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Ribeiro, Edna
Ladeira, Carina
Viegas, Susana
dc.subject.por.fl_str_mv bisphenol A (BPA)
endocrine disruptor
genotoxicity
occupational exposure
exposure assessment
health effects
topic bisphenol A (BPA)
endocrine disruptor
genotoxicity
occupational exposure
exposure assessment
health effects
description Review
publishDate 2017
dc.date.none.fl_str_mv 2017-10-04T15:12:32Z
2017
2017-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.5/14143
url http://hdl.handle.net/10400.5/14143
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Toxics 2017, 5, 22
10.3390/toxics5030022
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833601937224761344

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