Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model

Bibliographic Details
Main Author: Taboada, Bruna Rafaela Pereira
Publication Date: 2016
Other Authors: Monteiro, Fernando C., Lima, Rui A.
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10198/16722
Summary: This study aimed to assess the motion and its deformation index (DI) of red blood cells (RBCs) flowing through a microchannel with a microstenosis using an image analysis-based method. For this purpose, a microchannel having a smooth contraction was used and the images were captured by a standard high-speed microscopy system. An automatic image-processing and analysing method was developed in a MATLAB environment to not only track the motion of RBCs but also measure the DI along the microchannel. The keyhole model, tested in this study, proved to be a promising technique to automatically track individual RBCs in microchannels.
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spelling Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole modelAutomatic trackingDeformation indexKeyhole modelMicrofluidsRed blood cellsThis study aimed to assess the motion and its deformation index (DI) of red blood cells (RBCs) flowing through a microchannel with a microstenosis using an image analysis-based method. For this purpose, a microchannel having a smooth contraction was used and the images were captured by a standard high-speed microscopy system. An automatic image-processing and analysing method was developed in a MATLAB environment to not only track the motion of RBCs but also measure the DI along the microchannel. The keyhole model, tested in this study, proved to be a promising technique to automatically track individual RBCs in microchannels.This study was financially supported by the Science and Technology Foundation (FCT), COMPETE, QREN and the European Union (FEDER) [grant numbers PTDC/SAU-BEB/ 105650/2008, PTDC/SAU-ENB/116929/2010, EXPL/EMS-SIS/ 2215/2013]Taylor & Francis GroupBiblioteca Digital do IPBTaboada, Bruna Rafaela PereiraMonteiro, Fernando C.Lima, Rui A.2018-04-06T10:41:50Z20162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/16722engTaboada, B.; Monteiro, Fernando C.; Lima, R. (2016)- Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model. Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization. ISSN 2168-1163. 4:3-4, p. 229-2372168-116310.1080/21681163.2014.957868info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-25T12:06:34Zoai:bibliotecadigital.ipb.pt:10198/16722Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T11:33:16.914172Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model
title Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model
spellingShingle Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model
Taboada, Bruna Rafaela Pereira
Automatic tracking
Deformation index
Keyhole model
Microfluids
Red blood cells
title_short Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model
title_full Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model
title_fullStr Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model
title_full_unstemmed Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model
title_sort Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model
author Taboada, Bruna Rafaela Pereira
author_facet Taboada, Bruna Rafaela Pereira
Monteiro, Fernando C.
Lima, Rui A.
author_role author
author2 Monteiro, Fernando C.
Lima, Rui A.
author2_role author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Taboada, Bruna Rafaela Pereira
Monteiro, Fernando C.
Lima, Rui A.
dc.subject.por.fl_str_mv Automatic tracking
Deformation index
Keyhole model
Microfluids
Red blood cells
topic Automatic tracking
Deformation index
Keyhole model
Microfluids
Red blood cells
description This study aimed to assess the motion and its deformation index (DI) of red blood cells (RBCs) flowing through a microchannel with a microstenosis using an image analysis-based method. For this purpose, a microchannel having a smooth contraction was used and the images were captured by a standard high-speed microscopy system. An automatic image-processing and analysing method was developed in a MATLAB environment to not only track the motion of RBCs but also measure the DI along the microchannel. The keyhole model, tested in this study, proved to be a promising technique to automatically track individual RBCs in microchannels.
publishDate 2016
dc.date.none.fl_str_mv 2016
2016-01-01T00:00:00Z
2018-04-06T10:41:50Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/16722
url http://hdl.handle.net/10198/16722
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Taboada, B.; Monteiro, Fernando C.; Lima, R. (2016)- Automatic tracking and deformation measurements of red blood cells flowing through a microchannel with a microstenosis: the keyhole model. Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization. ISSN 2168-1163. 4:3-4, p. 229-237
2168-1163
10.1080/21681163.2014.957868
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis Group
publisher.none.fl_str_mv Taylor & Francis Group
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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