Injectable gellan gum-based hydrogels for intervertebral disc regeneration
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
| Texto Completo: | http://hdl.handle.net/1822/12795 |
Resumo: | Intervertebral disc (IVD) degeneration is a challenging pathology that, due to the inefficiency of the current treatments, urgently demands for the development of new regenerative approaches[1]. The best viable implant material for nucleus pulposus (NP) regeneration has yet to be identified, but it is believed that biodegradable hydrogelbased materials are promising candidates[2]. In this work, we are proposing the use of ionic- and photocrosslinked methacrylated gellan gum (GG-MA) hydrogels as potential acellular and cellular injectable scaffolds for IVD regeneration. |
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Injectable gellan gum-based hydrogels for intervertebral disc regenerationGellan gumIntervertebralIntervertebral disc (IVD) degeneration is a challenging pathology that, due to the inefficiency of the current treatments, urgently demands for the development of new regenerative approaches[1]. The best viable implant material for nucleus pulposus (NP) regeneration has yet to be identified, but it is believed that biodegradable hydrogelbased materials are promising candidates[2]. In this work, we are proposing the use of ionic- and photocrosslinked methacrylated gellan gum (GG-MA) hydrogels as potential acellular and cellular injectable scaffolds for IVD regeneration.Universidade do MinhoSilva-Correia, JoanaOliveira, Joaquim M.Caridade, S. G.Oliveira, J. T.Sousa, R. A.Mano, J. F.Reis, R. L.2011-062011-06-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/12795eng0213-39111info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-11T07:01:30Zoai:repositorium.sdum.uminho.pt:1822/12795Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T16:12:40.545709Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
| dc.title.none.fl_str_mv |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
| title |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
| spellingShingle |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration Silva-Correia, Joana Gellan gum Intervertebral |
| title_short |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
| title_full |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
| title_fullStr |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
| title_full_unstemmed |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
| title_sort |
Injectable gellan gum-based hydrogels for intervertebral disc regeneration |
| author |
Silva-Correia, Joana |
| author_facet |
Silva-Correia, Joana Oliveira, Joaquim M. Caridade, S. G. Oliveira, J. T. Sousa, R. A. Mano, J. F. Reis, R. L. |
| author_role |
author |
| author2 |
Oliveira, Joaquim M. Caridade, S. G. Oliveira, J. T. Sousa, R. A. Mano, J. F. Reis, R. L. |
| author2_role |
author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade do Minho |
| dc.contributor.author.fl_str_mv |
Silva-Correia, Joana Oliveira, Joaquim M. Caridade, S. G. Oliveira, J. T. Sousa, R. A. Mano, J. F. Reis, R. L. |
| dc.subject.por.fl_str_mv |
Gellan gum Intervertebral |
| topic |
Gellan gum Intervertebral |
| description |
Intervertebral disc (IVD) degeneration is a challenging pathology that, due to the inefficiency of the current treatments, urgently demands for the development of new regenerative approaches[1]. The best viable implant material for nucleus pulposus (NP) regeneration has yet to be identified, but it is believed that biodegradable hydrogelbased materials are promising candidates[2]. In this work, we are proposing the use of ionic- and photocrosslinked methacrylated gellan gum (GG-MA) hydrogels as potential acellular and cellular injectable scaffolds for IVD regeneration. |
| publishDate |
2011 |
| dc.date.none.fl_str_mv |
2011-06 2011-06-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/1822/12795 |
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http://hdl.handle.net/1822/12795 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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0213-39111 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
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