Esophageal Atresia at Daniel de Matos Maternity: A Fifteen-year Review

Bibliographic Details
Main Author: Pedro, Beatriz
Publication Date: 2025
Other Authors: Castelo, Rui, Oliveira, Guiomar
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: https://doi.org/10.29315/gm.784
Summary: Introduction: Esophageal atresia (EA) is a rare congenital malformation, with mainly postnatal diagnosis, although prenatal suspicion has improved. Until surgery, these newborns need monitoring in Neonatal Intensive Care Unit (NICU). Despite mortality reduction, morbidity remains a concern. The aim of this study was to characterize the prenatal, delivery and postnatal data of EA newborns at a level three reference center.Methods: An anonymized retrospective study was performed from eighteen newborns diagnosed with EA, born between January 2007 – December 2021, who were admitted to the NICU of a level three center. Data was collected using neonate´s medical records, compiled with Microsoft Excel and analyzed by IBM SPSS statistics.Results: There was no sex prevalence and no preponderance in advanced mother’s age. Prenatal suspicion consisted on ultrasound (polyhydramnios/stomach non-visualization), where EA type A had higher reports. Higher incidence of EA was found in premature newborns. An association between lower gestational age and the presence of polyhydramnios was found. Other congenital anomalies associated were common, mostly cardiac. The prevalence of EA type C and short-gap was found. Gastroesophageal reflux and esophageal stenosis were frequentcomorbidities.Conclusion: Improvement in prenatal and postnatal surveillance/evaluation could reduce morbimortality and improve management of these neonates. As mortality reduced, further research is needed to target morbidity and quality of life.
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spelling Esophageal Atresia at Daniel de Matos Maternity: A Fifteen-year ReviewAtresia Esofágica na Maternidade Daniel de Matos: Uma Revisão de Quinze AnosAtresia EsofágicaDiagnóstico Pré-NatalFístula TraqueoesofágicaRecém-NascidoEsophageal AtresiaInfant, NewbornPrenatal DiagnosisTracheoesophageal FistulaIntroduction: Esophageal atresia (EA) is a rare congenital malformation, with mainly postnatal diagnosis, although prenatal suspicion has improved. Until surgery, these newborns need monitoring in Neonatal Intensive Care Unit (NICU). Despite mortality reduction, morbidity remains a concern. The aim of this study was to characterize the prenatal, delivery and postnatal data of EA newborns at a level three reference center.Methods: An anonymized retrospective study was performed from eighteen newborns diagnosed with EA, born between January 2007 – December 2021, who were admitted to the NICU of a level three center. Data was collected using neonate´s medical records, compiled with Microsoft Excel and analyzed by IBM SPSS statistics.Results: There was no sex prevalence and no preponderance in advanced mother’s age. Prenatal suspicion consisted on ultrasound (polyhydramnios/stomach non-visualization), where EA type A had higher reports. Higher incidence of EA was found in premature newborns. An association between lower gestational age and the presence of polyhydramnios was found. Other congenital anomalies associated were common, mostly cardiac. The prevalence of EA type C and short-gap was found. Gastroesophageal reflux and esophageal stenosis were frequentcomorbidities.Conclusion: Improvement in prenatal and postnatal surveillance/evaluation could reduce morbimortality and improve management of these neonates. As mortality reduced, further research is needed to target morbidity and quality of life.Introdução: A atresia esofágica (EA) é uma malformação congénita rara, com diagnóstico maioritariamente pós-natal, apesar de a suspeita pré-natal ter melhorado ao longo dos anos. Até à realização da cirurgia, estes recém-nascidos precisam de monitorização numa Unidade de Cuidados Intensivos Neonatais (NICU). Apesar da redução na mortalidade, a morbilidade mantém-se uma preocupação. O objetivo deste estudo foi caraterizar dados pré-natais, do parto e pós-natais de recém-nascidos com EA num centro de referência de nível três.Métodos: Um estudo retrospetivo anonimizado foi realizado através de dados de dezoito recém-nascidos diagnosticados com EA, nascidos entre janeiro 2007 – dezembro 2021, que foram admitidos na NICU de um centro de referência nível três. Os dados foram colhidos através de registos médicos dos recém-nascidos, compilados no Microsoft Excel e analisados pelo IBM SPSS statistics.Resultados: Não houve prevalência entre sexos nem na idade materna avançada. A suspeita pré-natal consistiu na ecografia (polihidrâmnios/não visualização do estomago), onde a EA tipo A teve maiores resultados. Uma maior incidência de EA foi encontrada em recém-nascidos prematuros. Uma associação entre idades gestacionais menores a presença de polihidrâmnios foi encontrada. Outras anomalias associadas foram comuns, principalmente cardíacas. Uma prevalência de EA tipo C e hiato-curto foram encontradas. O refluxo gastroesofágico e estenose esofágica foram comorbilidades frequentes.Conclusão: Melhoria na vigilância/avaliação pré-natal e pós-natal poderia reduzir a morbimortalidade e melhorar a gestão destes recém-nascidos. Com a redução na mortalidade, novos estudos são necessários para focarem na morbilidade e qualidade de vida.CUF Academic Center2025-05-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.29315/gm.784https://doi.org/10.29315/gm.784Gazeta Médica; Ahead of PrintGazeta Médica; Ahead of Print2184-06282183-8135reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPenghttps://www.gazetamedica.pt/index.php/gazeta/article/view/784https://www.gazetamedica.pt/index.php/gazeta/article/view/784/535Copyright (c) 2015 Gazeta Médicainfo:eu-repo/semantics/openAccessPedro, BeatrizCastelo, RuiOliveira, Guiomar2025-05-24T04:45:36Zoai:ojs.pkp.sfu.ca:article/784Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T07:36:25.377997Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Esophageal Atresia at Daniel de Matos Maternity: A Fifteen-year Review
Atresia Esofágica na Maternidade Daniel de Matos: Uma Revisão de Quinze Anos
title Esophageal Atresia at Daniel de Matos Maternity: A Fifteen-year Review
spellingShingle Esophageal Atresia at Daniel de Matos Maternity: A Fifteen-year Review
Pedro, Beatriz
Atresia Esofágica
Diagnóstico Pré-Natal
Fístula Traqueoesofágica
Recém-Nascido
Esophageal Atresia
Infant, Newborn
Prenatal Diagnosis
Tracheoesophageal Fistula
title_short Esophageal Atresia at Daniel de Matos Maternity: A Fifteen-year Review
title_full Esophageal Atresia at Daniel de Matos Maternity: A Fifteen-year Review
title_fullStr Esophageal Atresia at Daniel de Matos Maternity: A Fifteen-year Review
title_full_unstemmed Esophageal Atresia at Daniel de Matos Maternity: A Fifteen-year Review
title_sort Esophageal Atresia at Daniel de Matos Maternity: A Fifteen-year Review
author Pedro, Beatriz
author_facet Pedro, Beatriz
Castelo, Rui
Oliveira, Guiomar
author_role author
author2 Castelo, Rui
Oliveira, Guiomar
author2_role author
author
dc.contributor.author.fl_str_mv Pedro, Beatriz
Castelo, Rui
Oliveira, Guiomar
dc.subject.por.fl_str_mv Atresia Esofágica
Diagnóstico Pré-Natal
Fístula Traqueoesofágica
Recém-Nascido
Esophageal Atresia
Infant, Newborn
Prenatal Diagnosis
Tracheoesophageal Fistula
topic Atresia Esofágica
Diagnóstico Pré-Natal
Fístula Traqueoesofágica
Recém-Nascido
Esophageal Atresia
Infant, Newborn
Prenatal Diagnosis
Tracheoesophageal Fistula
description Introduction: Esophageal atresia (EA) is a rare congenital malformation, with mainly postnatal diagnosis, although prenatal suspicion has improved. Until surgery, these newborns need monitoring in Neonatal Intensive Care Unit (NICU). Despite mortality reduction, morbidity remains a concern. The aim of this study was to characterize the prenatal, delivery and postnatal data of EA newborns at a level three reference center.Methods: An anonymized retrospective study was performed from eighteen newborns diagnosed with EA, born between January 2007 – December 2021, who were admitted to the NICU of a level three center. Data was collected using neonate´s medical records, compiled with Microsoft Excel and analyzed by IBM SPSS statistics.Results: There was no sex prevalence and no preponderance in advanced mother’s age. Prenatal suspicion consisted on ultrasound (polyhydramnios/stomach non-visualization), where EA type A had higher reports. Higher incidence of EA was found in premature newborns. An association between lower gestational age and the presence of polyhydramnios was found. Other congenital anomalies associated were common, mostly cardiac. The prevalence of EA type C and short-gap was found. Gastroesophageal reflux and esophageal stenosis were frequentcomorbidities.Conclusion: Improvement in prenatal and postnatal surveillance/evaluation could reduce morbimortality and improve management of these neonates. As mortality reduced, further research is needed to target morbidity and quality of life.
publishDate 2025
dc.date.none.fl_str_mv 2025-05-23
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.29315/gm.784
https://doi.org/10.29315/gm.784
url https://doi.org/10.29315/gm.784
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.gazetamedica.pt/index.php/gazeta/article/view/784
https://www.gazetamedica.pt/index.php/gazeta/article/view/784/535
dc.rights.driver.fl_str_mv Copyright (c) 2015 Gazeta Médica
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2015 Gazeta Médica
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv CUF Academic Center
publisher.none.fl_str_mv CUF Academic Center
dc.source.none.fl_str_mv Gazeta Médica; Ahead of Print
Gazeta Médica; Ahead of Print
2184-0628
2183-8135
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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