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Recent advances in magnetic electrospun nanofibers for cancer theranostics application

Bibliographic Details
Main Author: Soares, Paula I. P.
Publication Date: 2021
Other Authors: Borges, João Paulo
Format: Other
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/129536
Summary: CEECIND.03189.2020
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spelling Recent advances in magnetic electrospun nanofibers for cancer theranostics applicationCancer theranosticsElectrospinningIron oxide nanoparticlesMagnetic fluid hyperthermiaNanofibersMaterials Science(all)SDG 3 - Good Health and Well-beingCEECIND.03189.2020Cancer theranostics is a recent concept that aims to combine in the same device diagnostic and therapeutic features. Magnetic nanoparticles (mNPs) are commonly used as a critical part of these systems due to their ability to respond to an external magnetic field. Consequently, mNPs can generate heat when an alternating magnetic field is applied and enhance image contrast in magnetic resonance. However, direct administration of mNPs intravenously or directly in the tumor can lead to undesired side effects because of mNP elimination by macrophages or leakage to healthy tissues. Therefore, mNPs can be retained in a polymeric nanofibrous mesh, thus preventing misplacing or loss of mNPs. Furthermore, these magnetic nanofibers can be directly implanted in the tumor site, thus ensuring high mNPs loading and higher magnetic response. In addition, polymeric nanofibers produced by electrospinning are frequently used to maintain a sustained drug release in the tumor site. Therefore, a magnetic polymeric nanofiber produced by electrospinning is an ideal nanosystem for cancer theranostics application. This review summarizes the most recent developments of magnetic nanofibers produced by electrospinning for cancer theranostics applications.CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)DCM - Departamento de Ciência dos MateriaisRUNSoares, Paula I. P.Borges, João Paulo2021-12-20T23:17:58Z2021-122021-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttp://hdl.handle.net/10362/129536eng1002-0071PURE: 35482535https://doi.org/10.1016/j.pnsc.2021.11.003info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T17:57:40Zoai:run.unl.pt:10362/129536Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:28:55.295835Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Recent advances in magnetic electrospun nanofibers for cancer theranostics application
title Recent advances in magnetic electrospun nanofibers for cancer theranostics application
spellingShingle Recent advances in magnetic electrospun nanofibers for cancer theranostics application
Soares, Paula I. P.
Cancer theranostics
Electrospinning
Iron oxide nanoparticles
Magnetic fluid hyperthermia
Nanofibers
Materials Science(all)
SDG 3 - Good Health and Well-being
title_short Recent advances in magnetic electrospun nanofibers for cancer theranostics application
title_full Recent advances in magnetic electrospun nanofibers for cancer theranostics application
title_fullStr Recent advances in magnetic electrospun nanofibers for cancer theranostics application
title_full_unstemmed Recent advances in magnetic electrospun nanofibers for cancer theranostics application
title_sort Recent advances in magnetic electrospun nanofibers for cancer theranostics application
author Soares, Paula I. P.
author_facet Soares, Paula I. P.
Borges, João Paulo
author_role author
author2 Borges, João Paulo
author2_role author
dc.contributor.none.fl_str_mv CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
DCM - Departamento de Ciência dos Materiais
RUN
dc.contributor.author.fl_str_mv Soares, Paula I. P.
Borges, João Paulo
dc.subject.por.fl_str_mv Cancer theranostics
Electrospinning
Iron oxide nanoparticles
Magnetic fluid hyperthermia
Nanofibers
Materials Science(all)
SDG 3 - Good Health and Well-being
topic Cancer theranostics
Electrospinning
Iron oxide nanoparticles
Magnetic fluid hyperthermia
Nanofibers
Materials Science(all)
SDG 3 - Good Health and Well-being
description CEECIND.03189.2020
publishDate 2021
dc.date.none.fl_str_mv 2021-12-20T23:17:58Z
2021-12
2021-12-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/other
format other
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/129536
url http://hdl.handle.net/10362/129536
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1002-0071
PURE: 35482535
https://doi.org/10.1016/j.pnsc.2021.11.003
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
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reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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