CO2 laser surgery for the treatment of glottic cancer

Detalhes bibliográficos
Autor(a) principal: Jerónimo, Alexandra
Data de Publicação: 2011
Outros Autores: Cavilhas, Pedro, Oliveira, Luís, Montalvão, Pedro, Magalhães, Miguel
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: https://doi.org/10.34631/sporl.193
Resumo: Introduction: Transoral laser microsurgery (TLM) can beconsidered a valid alternative in the treatment of glotticcancer.Matherial and Methods: Retrospective study, considering allpatients treated with TLM, from January 2000 to December2005. Patients were considered for the present study if theyunderwent laser surgery as primary treatment of glotticcancer.Results: 45 patients: CIS (n=9), T1a (n=29), T1b (n=5), T2(n=1), T3 (n=1). The mean duration of follow-up was 63,3months. The rate of global local recurrence was 22,2%, withthe anterior commissure involvement being responsible for40% of the recurrences. The 5-year overall survival and the5-year disease-free survival were 82,2%, and the laryngealpreservation rate was 89,2%.Conclusion: This study supports the role of TLM in treatingearly-stage glottic cancer. The highest recurrence rates occurwith positive margins and anterior commissure involvement.Advanced glottic cancers are not a consensual indication forlaser surgery, usually with worse oncological outcome.
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spelling CO2 laser surgery for the treatment of glottic cancerCirurgia laser CO2 no tratamento de tumores malignos glóticosglottic cancertransoral CO2 laser microsurgeryanterior commissuremargin statustumor maligno glóticomicrocirurgia transoral laser CO2comissura anteriormargem cirúrgicaIntroduction: Transoral laser microsurgery (TLM) can beconsidered a valid alternative in the treatment of glotticcancer.Matherial and Methods: Retrospective study, considering allpatients treated with TLM, from January 2000 to December2005. Patients were considered for the present study if theyunderwent laser surgery as primary treatment of glotticcancer.Results: 45 patients: CIS (n=9), T1a (n=29), T1b (n=5), T2(n=1), T3 (n=1). The mean duration of follow-up was 63,3months. The rate of global local recurrence was 22,2%, withthe anterior commissure involvement being responsible for40% of the recurrences. The 5-year overall survival and the5-year disease-free survival were 82,2%, and the laryngealpreservation rate was 89,2%.Conclusion: This study supports the role of TLM in treatingearly-stage glottic cancer. The highest recurrence rates occurwith positive margins and anterior commissure involvement.Advanced glottic cancers are not a consensual indication forlaser surgery, usually with worse oncological outcome.Introdução: A microcirurgia transoral com laser CO2 (MTOL) éuma alternativa no tratamento de tumores malignos glóticos.Material e Métodos: Estudo retrospectivo dos doentessubmetidos a MTOL, de Janeiro de 2000 a Dezembro de2005, incluindo apenas os casos em que o laser constituiu otratamento primário.Resultados: Total de 45 doentes: CIS (n=9), T1a (n=29), T1b(n=5), T2 (n=1), T3 (n=1), com follow-up médio de 63,5meses. Obteve-se uma taxa de recidiva local global de 22,2%,verificando-se o envolvimento da comissura anterior em 40%das recidivas. A taxa de sobrevida global e livre de doença, aos5 anos, foi de 82,2%, com uma taxa de preservação laríngeade 89,2%.Conclusão: O laser CO2 é uma opção eficaz na abordagem deneoplasias glóticas em estadio inicial. A taxa de recidiva tumoralé maior quando há tumor na margem e/ou envolvimento dacomissura anterior. Tumores glóticos localmente avançadossão mais susceptíveis ao insucesso terapêutico por estatécnica.Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço2011-12-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.34631/sporl.193https://doi.org/10.34631/sporl.193Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 49 No. 4 (2011): Dezembro; 235-241Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 49 Núm. 4 (2011): Dezembro; 235-241Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 49 N.º 4 (2011): Dezembro; 235-2412184-6499reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporhttps://journalsporl.com/index.php/sporl/article/view/2550https://journalsporl.com/index.php/sporl/article/view/2550/555Jerónimo, AlexandraCavilhas, PedroOliveira, LuísMontalvão, PedroMagalhães, Miguelinfo:eu-repo/semantics/openAccess2024-06-06T12:59:05Zoai:journalsporl.com:article/2550Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:53:50.869909Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv CO2 laser surgery for the treatment of glottic cancer
Cirurgia laser CO2 no tratamento de tumores malignos glóticos
title CO2 laser surgery for the treatment of glottic cancer
spellingShingle CO2 laser surgery for the treatment of glottic cancer
Jerónimo, Alexandra
glottic cancer
transoral CO2 laser microsurgery
anterior commissure
margin status
tumor maligno glótico
microcirurgia transoral laser CO2
comissura anterior
margem cirúrgica
title_short CO2 laser surgery for the treatment of glottic cancer
title_full CO2 laser surgery for the treatment of glottic cancer
title_fullStr CO2 laser surgery for the treatment of glottic cancer
title_full_unstemmed CO2 laser surgery for the treatment of glottic cancer
title_sort CO2 laser surgery for the treatment of glottic cancer
author Jerónimo, Alexandra
author_facet Jerónimo, Alexandra
Cavilhas, Pedro
Oliveira, Luís
Montalvão, Pedro
Magalhães, Miguel
author_role author
author2 Cavilhas, Pedro
Oliveira, Luís
Montalvão, Pedro
Magalhães, Miguel
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Jerónimo, Alexandra
Cavilhas, Pedro
Oliveira, Luís
Montalvão, Pedro
Magalhães, Miguel
dc.subject.por.fl_str_mv glottic cancer
transoral CO2 laser microsurgery
anterior commissure
margin status
tumor maligno glótico
microcirurgia transoral laser CO2
comissura anterior
margem cirúrgica
topic glottic cancer
transoral CO2 laser microsurgery
anterior commissure
margin status
tumor maligno glótico
microcirurgia transoral laser CO2
comissura anterior
margem cirúrgica
description Introduction: Transoral laser microsurgery (TLM) can beconsidered a valid alternative in the treatment of glotticcancer.Matherial and Methods: Retrospective study, considering allpatients treated with TLM, from January 2000 to December2005. Patients were considered for the present study if theyunderwent laser surgery as primary treatment of glotticcancer.Results: 45 patients: CIS (n=9), T1a (n=29), T1b (n=5), T2(n=1), T3 (n=1). The mean duration of follow-up was 63,3months. The rate of global local recurrence was 22,2%, withthe anterior commissure involvement being responsible for40% of the recurrences. The 5-year overall survival and the5-year disease-free survival were 82,2%, and the laryngealpreservation rate was 89,2%.Conclusion: This study supports the role of TLM in treatingearly-stage glottic cancer. The highest recurrence rates occurwith positive margins and anterior commissure involvement.Advanced glottic cancers are not a consensual indication forlaser surgery, usually with worse oncological outcome.
publishDate 2011
dc.date.none.fl_str_mv 2011-12-28
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.34631/sporl.193
https://doi.org/10.34631/sporl.193
url https://doi.org/10.34631/sporl.193
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://journalsporl.com/index.php/sporl/article/view/2550
https://journalsporl.com/index.php/sporl/article/view/2550/555
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço
publisher.none.fl_str_mv Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço
dc.source.none.fl_str_mv Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 49 No. 4 (2011): Dezembro; 235-241
Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 49 Núm. 4 (2011): Dezembro; 235-241
Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 49 N.º 4 (2011): Dezembro; 235-241
2184-6499
reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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