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Protein structural alterations in diabetic cavernosal tissue - their role in erectile dysfunction progression

Bibliographic Details
Main Author: Castela, A.
Publication Date: 2011
Other Authors: Soares, R., Gomes, P., Coelho, Pedro, Fernandes, Ruben
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.22/18624
Summary: Erectile dysfunction (ED) is one of the most prevalent complications in diabetic men. Hyperglicemia contributes to increased oxidative stress (OS) in diabetic corpus cavernosum (CC), promoting alterations in cavernosal cellular components. However, it remains unclear the mechanisms by which OS induces modifi cations in diabetic penile tissue with the progression of diabetes and its role in the devel opment of ED. We intended to evaluate/quantify CC protein structural modifi cation caused by OS in an early and late stage of diabetes.
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spelling Protein structural alterations in diabetic cavernosal tissue - their role in erectile dysfunction progressionErectile dysfunctionDiabetesErectile dysfunction (ED) is one of the most prevalent complications in diabetic men. Hyperglicemia contributes to increased oxidative stress (OS) in diabetic corpus cavernosum (CC), promoting alterations in cavernosal cellular components. However, it remains unclear the mechanisms by which OS induces modifi cations in diabetic penile tissue with the progression of diabetes and its role in the devel opment of ED. We intended to evaluate/quantify CC protein structural modifi cation caused by OS in an early and late stage of diabetes.ElsevierREPOSITÓRIO P.PORTOCastela, A.Soares, R.Gomes, P.Coelho, PedroFernandes, Ruben2021-09-29T13:34:02Z2011-122011-12-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10400.22/18624eng1743-609510.26537/recipp-ess-cqb-001info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-07T10:17:05Zoai:recipp.ipp.pt:10400.22/18624Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T00:46:26.890641Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Protein structural alterations in diabetic cavernosal tissue - their role in erectile dysfunction progression
title Protein structural alterations in diabetic cavernosal tissue - their role in erectile dysfunction progression
spellingShingle Protein structural alterations in diabetic cavernosal tissue - their role in erectile dysfunction progression
Castela, A.
Erectile dysfunction
Diabetes
title_short Protein structural alterations in diabetic cavernosal tissue - their role in erectile dysfunction progression
title_full Protein structural alterations in diabetic cavernosal tissue - their role in erectile dysfunction progression
title_fullStr Protein structural alterations in diabetic cavernosal tissue - their role in erectile dysfunction progression
title_full_unstemmed Protein structural alterations in diabetic cavernosal tissue - their role in erectile dysfunction progression
title_sort Protein structural alterations in diabetic cavernosal tissue - their role in erectile dysfunction progression
author Castela, A.
author_facet Castela, A.
Soares, R.
Gomes, P.
Coelho, Pedro
Fernandes, Ruben
author_role author
author2 Soares, R.
Gomes, P.
Coelho, Pedro
Fernandes, Ruben
author2_role author
author
author
author
dc.contributor.none.fl_str_mv REPOSITÓRIO P.PORTO
dc.contributor.author.fl_str_mv Castela, A.
Soares, R.
Gomes, P.
Coelho, Pedro
Fernandes, Ruben
dc.subject.por.fl_str_mv Erectile dysfunction
Diabetes
topic Erectile dysfunction
Diabetes
description Erectile dysfunction (ED) is one of the most prevalent complications in diabetic men. Hyperglicemia contributes to increased oxidative stress (OS) in diabetic corpus cavernosum (CC), promoting alterations in cavernosal cellular components. However, it remains unclear the mechanisms by which OS induces modifi cations in diabetic penile tissue with the progression of diabetes and its role in the devel opment of ED. We intended to evaluate/quantify CC protein structural modifi cation caused by OS in an early and late stage of diabetes.
publishDate 2011
dc.date.none.fl_str_mv 2011-12
2011-12-01T00:00:00Z
2021-09-29T13:34:02Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/18624
url http://hdl.handle.net/10400.22/18624
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1743-6095
10.26537/recipp-ess-cqb-001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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