Antifouling, antibiofilm and ecotoxicological evaluation of paints with marine actinomycetes extracts

• Autor(a) principal: Maria Carvalho Torres Pereira, Isabel
• Data de Publicação: 2024
• Tipo de documento: Dissertação
• Idioma: eng
• Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
• Texto Completo: http://hdl.handle.net/10362/176407
• topic: marine biofouling; antifouling; antibiofilm; napyradiomycins; marinones; eco-friendly nautical paints; Domínio/Área Científica::Ciências Naturais::Ciências Químicas

Marine biofouling has posed challenges to the nautical industry and all the industries that have underwater infrastructures, contributing to negative environmental impacts. Currently, main mitigation strategies of this phenomenon include antifouling methods with biocidal compounds; however, their toxicity has inspired a search for sustainable, cost-effective and environmentally safe alternatives to combat this phenome-non. Natural compounds from marine organisms such as actinomycetes represent a promising source for environmentally friendly antifouling compounds. This study explored the antifouling and antibiofilm potential of crude extracts derived from actinomycetes containing secondary metabolites with antifouling activity as additives to nautical paints. Exposure bioassays on model marine organisms were conducted to evaluate the antifouling capacity of the extracts containing napyradiomycins or marinones when incorporated in a biocide free marine paint. In addition, the antibiofilm capacity of the paints with the extracts was also evaluated. The paints containing the extracts in their composition demonstrated good antifouling power, as well as the ability to inhibit bio-film formation, thus being strong candidates for use as agents to combat both marine microfouling and macrofouling. Biochemical assays on oxidative stress biomarkers (including GST, SOD, CAT, TAC and lipid peroxidation) further suggested napyradiomycin-based and marinone-based paints as eco-friendly products, being marinone-derived paint safer for marine species compared to the paint containing napyradiomycins.