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Cochrane corner : perioperative beta-blockers for preventing surgery-related mortality and morbidity

Bibliographic Details
Main Author: Alegria, Sofia
Publication Date: 2019
Other Authors: Costa, João, Carneiro, António Vaz, Caldeira, Daniel
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10451/41728
Summary: © 2019 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U.
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network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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spelling Cochrane corner : perioperative beta-blockers for preventing surgery-related mortality and morbidityCochrane corner : utilização de betabloqueantes no período perioperatório para prevenção de mortalidade e morbilidade relacionadas com a cirurgiaBeta-blockersSurgeryMortality© 2019 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U.Randomized controlled trials have yielded conflicting results regarding the impact of beta-blockers on perioperative cardiovascular morbidity and mortality. This Cochrane systematic review assessed the impact of this intervention on mortality and cardiovascular events. Eighty-eight randomized controlled trials with 19 161 participants were included (53 trials on cardiac surgery and 35 trials on non-cardiac surgery). In cardiac surgery perioperative beta-blockers had a protective effect against supraventricular and ventricular arrhythmias but had no significant effect on mortality or on the occurrence of acute myocardial infarction (AMI), stroke, heart failure, hypotension or bradycardia. In non-cardiac surgery, beta-blockers had a protective effect against AMI and arrhythmias, but this was counterbalanced by an increased risk of death and stroke. In conclusion, perioperative use of beta-blockers appears overall to be beneficial in cardiac surgery. However, in non-cardiac surgery the substantial reduction in rhythm disturbances and AMI appears to be offset by an increase in mortality and stroke, and so the systematic use of beta-blockers in this setting is not recommended.ElsevierRepositório da Universidade de LisboaAlegria, SofiaCosta, JoãoCarneiro, António VazCaldeira, Daniel2020-02-10T15:33:20Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/41728engRev Port Cardiol. 2019;38(10):691-6940870-255110.1016/j.repc.2018.10.014info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-03-17T14:16:19Zoai:repositorio.ulisboa.pt:10451/41728Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-29T03:07:07.842300Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Cochrane corner : perioperative beta-blockers for preventing surgery-related mortality and morbidity
Cochrane corner : utilização de betabloqueantes no período perioperatório para prevenção de mortalidade e morbilidade relacionadas com a cirurgia
title Cochrane corner : perioperative beta-blockers for preventing surgery-related mortality and morbidity
spellingShingle Cochrane corner : perioperative beta-blockers for preventing surgery-related mortality and morbidity
Alegria, Sofia
Beta-blockers
Surgery
Mortality
title_short Cochrane corner : perioperative beta-blockers for preventing surgery-related mortality and morbidity
title_full Cochrane corner : perioperative beta-blockers for preventing surgery-related mortality and morbidity
title_fullStr Cochrane corner : perioperative beta-blockers for preventing surgery-related mortality and morbidity
title_full_unstemmed Cochrane corner : perioperative beta-blockers for preventing surgery-related mortality and morbidity
title_sort Cochrane corner : perioperative beta-blockers for preventing surgery-related mortality and morbidity
author Alegria, Sofia
author_facet Alegria, Sofia
Costa, João
Carneiro, António Vaz
Caldeira, Daniel
author_role author
author2 Costa, João
Carneiro, António Vaz
Caldeira, Daniel
author2_role author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Alegria, Sofia
Costa, João
Carneiro, António Vaz
Caldeira, Daniel
dc.subject.por.fl_str_mv Beta-blockers
Surgery
Mortality
topic Beta-blockers
Surgery
Mortality
description © 2019 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
2020-02-10T15:33:20Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/41728
url http://hdl.handle.net/10451/41728
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Rev Port Cardiol. 2019;38(10):691-694
0870-2551
10.1016/j.repc.2018.10.014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
_version_ 1833601600412712960

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