Cation-mediated gelation of the fucose-rich polysaccharide FucoPol

Detalhes bibliográficos
Autor(a) principal: Fialho, Letícia
Data de Publicação: 2021
Outros Autores: Araújo, Diana, Alves, Vitor D., Roma-Rodrigues, Catarina, Baptista, Pedro V., Fernandes, Alexandra R., Freitas, Filomena, Reis, Maria A. M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: http://hdl.handle.net/10362/93177
Resumo: FCT/MEC (UID/Multi/04378/2019). PEst-OE/AGR/UI0245/2014. POCI-01-0145-FEDER-007728 and POCI-01-0145-FEDER - 007265. SFRH/BD/140829/2018. SFRH/BPD/124612/2016.
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spelling Cation-mediated gelation of the fucose-rich polysaccharide FucoPolpreparation and characterization of hydrogel beads and their cytotoxicity assessmentcytotoxicityFucoPolhydrogel beadsAnalytical ChemistryChemical Engineering(all)Polymers and PlasticsFCT/MEC (UID/Multi/04378/2019). PEst-OE/AGR/UI0245/2014. POCI-01-0145-FEDER-007728 and POCI-01-0145-FEDER - 007265. SFRH/BD/140829/2018. SFRH/BPD/124612/2016.This study describes for the first time the iron- and copper-mediated gelation of FucoPol, fucose-rich bacterial polysaccharide. The ability of FucoPol to gel in the presence of metal cations, including iron(III) and copper(II), was used for the preparation of hydrogel beads. Iron mediated the formation of stable and not cytotoxic gel beads, while copper resulted in fragile and cytotoxic ones. Copper-mediated beads coated with an iron-mediated gel layer were more stable and had reduced cytotoxicity. The resulting polymeric structures had differing morphology, physical properties and cytotoxicity, which support their use in several applications, including biomedicine, agriculture and bioremediation.UCIBIO - Applied Molecular Biosciences UnitDQ - Departamento de QuímicaDCV - Departamento de Ciências da VidaRUNFialho, LetíciaAraújo, DianaAlves, Vitor D.Roma-Rodrigues, CatarinaBaptista, Pedro V.Fernandes, Alexandra R.Freitas, FilomenaReis, Maria A. M.2022-10-24T00:32:48Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/93177eng0091-4037PURE: 15668277https://doi.org/10.1080/00914037.2019.1695205info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T17:43:39Zoai:run.unl.pt:10362/93177Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:14:56.216680Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Cation-mediated gelation of the fucose-rich polysaccharide FucoPol
preparation and characterization of hydrogel beads and their cytotoxicity assessment
title Cation-mediated gelation of the fucose-rich polysaccharide FucoPol
spellingShingle Cation-mediated gelation of the fucose-rich polysaccharide FucoPol
Fialho, Letícia
cytotoxicity
FucoPol
hydrogel beads
Analytical Chemistry
Chemical Engineering(all)
Polymers and Plastics
title_short Cation-mediated gelation of the fucose-rich polysaccharide FucoPol
title_full Cation-mediated gelation of the fucose-rich polysaccharide FucoPol
title_fullStr Cation-mediated gelation of the fucose-rich polysaccharide FucoPol
title_full_unstemmed Cation-mediated gelation of the fucose-rich polysaccharide FucoPol
title_sort Cation-mediated gelation of the fucose-rich polysaccharide FucoPol
author Fialho, Letícia
author_facet Fialho, Letícia
Araújo, Diana
Alves, Vitor D.
Roma-Rodrigues, Catarina
Baptista, Pedro V.
Fernandes, Alexandra R.
Freitas, Filomena
Reis, Maria A. M.
author_role author
author2 Araújo, Diana
Alves, Vitor D.
Roma-Rodrigues, Catarina
Baptista, Pedro V.
Fernandes, Alexandra R.
Freitas, Filomena
Reis, Maria A. M.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv UCIBIO - Applied Molecular Biosciences Unit
DQ - Departamento de Química
DCV - Departamento de Ciências da Vida
RUN
dc.contributor.author.fl_str_mv Fialho, Letícia
Araújo, Diana
Alves, Vitor D.
Roma-Rodrigues, Catarina
Baptista, Pedro V.
Fernandes, Alexandra R.
Freitas, Filomena
Reis, Maria A. M.
dc.subject.por.fl_str_mv cytotoxicity
FucoPol
hydrogel beads
Analytical Chemistry
Chemical Engineering(all)
Polymers and Plastics
topic cytotoxicity
FucoPol
hydrogel beads
Analytical Chemistry
Chemical Engineering(all)
Polymers and Plastics
description FCT/MEC (UID/Multi/04378/2019). PEst-OE/AGR/UI0245/2014. POCI-01-0145-FEDER-007728 and POCI-01-0145-FEDER - 007265. SFRH/BD/140829/2018. SFRH/BPD/124612/2016.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01T00:00:00Z
2022-10-24T00:32:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/93177
url http://hdl.handle.net/10362/93177
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0091-4037
PURE: 15668277
https://doi.org/10.1080/00914037.2019.1695205
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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