Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processes

Bibliographic Details
Main Author: Ribeiro, António E.
Publication Date: 2013
Other Authors: Graça, Nuno S., Ferreira, Alexandre, Rodrigues, Alírio, Pais, Luís S.
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10198/9140
Summary: This work will present a complete methodology concerning experimental, modelling and simulation results. Both the CHIRALPAK AD and CHIRALPAK IA CSP will be evaluated. The selection of the proper CSP/solvent combination for preparative operation will be fully study taking into account the screening strategy proposed by Zhang et al. Additional results include the measurement of nadolol stereoisomers solubilities, equilibrium adsorption data and fixed bed (breakthroughs) experiments. The complete screening of CSP/solvent combination will lead to the choice of the better solutions for the separation of nadolol stereoisomers, considering the target component or components to be obtained. Simulation and experimental results will be presented for the multicomponent separation of nadolol stereoisomers by multicolumn and Simulated Moving Bed adsorption processes.
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spelling Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processesChiral separationSimulated moving bedNadololChiralpak ADChiralpak IAThis work will present a complete methodology concerning experimental, modelling and simulation results. Both the CHIRALPAK AD and CHIRALPAK IA CSP will be evaluated. The selection of the proper CSP/solvent combination for preparative operation will be fully study taking into account the screening strategy proposed by Zhang et al. Additional results include the measurement of nadolol stereoisomers solubilities, equilibrium adsorption data and fixed bed (breakthroughs) experiments. The complete screening of CSP/solvent combination will lead to the choice of the better solutions for the separation of nadolol stereoisomers, considering the target component or components to be obtained. Simulation and experimental results will be presented for the multicomponent separation of nadolol stereoisomers by multicolumn and Simulated Moving Bed adsorption processes.Biblioteca Digital do IPBRibeiro, António E.Graça, Nuno S.Ferreira, AlexandreRodrigues, AlírioPais, Luís S.2014-01-13T13:32:17Z20132013-01-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10198/9140engRibeiro, António E.; Graça, Nuno S., Ferreira, Alexandre P.; Rodrigues, Alírio E.; Pais, L. S. (2013). Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processe. In FOA11 11th International Conference on the Fundamentals of Adsorption. Baltimore, Maryland, USAinfo:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-25T12:00:41Zoai:bibliotecadigital.ipb.pt:10198/9140Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T11:24:56.315711Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processes
title Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processes
spellingShingle Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processes
Ribeiro, António E.
Chiral separation
Simulated moving bed
Nadolol
Chiralpak AD
Chiralpak IA
title_short Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processes
title_full Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processes
title_fullStr Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processes
title_full_unstemmed Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processes
title_sort Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processes
author Ribeiro, António E.
author_facet Ribeiro, António E.
Graça, Nuno S.
Ferreira, Alexandre
Rodrigues, Alírio
Pais, Luís S.
author_role author
author2 Graça, Nuno S.
Ferreira, Alexandre
Rodrigues, Alírio
Pais, Luís S.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Ribeiro, António E.
Graça, Nuno S.
Ferreira, Alexandre
Rodrigues, Alírio
Pais, Luís S.
dc.subject.por.fl_str_mv Chiral separation
Simulated moving bed
Nadolol
Chiralpak AD
Chiralpak IA
topic Chiral separation
Simulated moving bed
Nadolol
Chiralpak AD
Chiralpak IA
description This work will present a complete methodology concerning experimental, modelling and simulation results. Both the CHIRALPAK AD and CHIRALPAK IA CSP will be evaluated. The selection of the proper CSP/solvent combination for preparative operation will be fully study taking into account the screening strategy proposed by Zhang et al. Additional results include the measurement of nadolol stereoisomers solubilities, equilibrium adsorption data and fixed bed (breakthroughs) experiments. The complete screening of CSP/solvent combination will lead to the choice of the better solutions for the separation of nadolol stereoisomers, considering the target component or components to be obtained. Simulation and experimental results will be presented for the multicomponent separation of nadolol stereoisomers by multicolumn and Simulated Moving Bed adsorption processes.
publishDate 2013
dc.date.none.fl_str_mv 2013
2013-01-01T00:00:00Z
2014-01-13T13:32:17Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/9140
url http://hdl.handle.net/10198/9140
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ribeiro, António E.; Graça, Nuno S., Ferreira, Alexandre P.; Rodrigues, Alírio E.; Pais, L. S. (2013). Multicomponent chiral separations by multicolumn and simulated moving bed adsorption processe. In FOA11 11th International Conference on the Fundamentals of Adsorption. Baltimore, Maryland, USA
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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