Development of a preoperative risk score on admission in surgical intermediate care unit in gastrointestinal cancer surgery

Bibliographic Details
Main Author: Fernandes, Antero
Publication Date: 2020
Other Authors: Rodrigues, Jéssica, Antunes, Luís, Lages, Patrícia, Santos, Carla Salomé, Moreira-Gonçalves, Daniel, Costa, Rafael S., Sousa, Joaquim Abreu, Dinis-Ribeiro, Mário, Santos, Lúcio Lara
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/114683
Summary: DSAIPA/DS/0042/2018 UID/DTP/00617/2019
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spelling Development of a preoperative risk score on admission in surgical intermediate care unit in gastrointestinal cancer surgerySDG 3 - Good Health and Well-beingDSAIPA/DS/0042/2018 UID/DTP/00617/2019Background: Gastrointestinal cancer surgery continues to be a significant cause of postoperative complications and mortality in high-risk patients. It is crucial to identify these patients. Our study aimed to evaluate the accuracy of specific perioperative risk assessment tools to predict postoperative complications, identifying the most informative variables and combining them to test their prediction ability as a new score. Methods: A prospective cohort study of digestive cancer surgical patients admitted to the surgical intermediate care unit of the Portuguese Oncology Institute of Porto, Portugal was conducted during the period January 2016 to April 2018. Demographic and medical information including sex, age, date from hospital admission, diagnosis, emergency or elective admission, and type of surgery, were collected. We analyzed and compared a set of measurements of surgical risk using the risk assessment instruments P-POSSUM Scoring, ACS NSQIP Surgical Risk Calculator, and ARISCAT Risk Score according to the outcomes classified by the Clavien-Dindo score. According to each risk score system, we studied the expected and observed post-operative complications. We performed a multivariable regression model retaining only the significant variables of these tools (age, gender, physiological P-Possum, and ACS NSQIP serious complication rate) and created a new score (MyIPOrisk-score). The predictive ability of each continuous score and the final panel obtained was evaluated using ROC curves and estimating the area under the curve (AUC). Results: We studied 341 patients. Our results showed that the predictive accuracy and agreement of P-POSSUM Scoring, ACS NSQIP Surgical Risk Calculator, and ARISCAT Risk Score were limited. The MyIPOrisk-score, shows to have greater discrimination ability than the one obtained with the other risk tools when evaluated individually (AUC = 0.808; 95% CI: 0.755-0.862). The expected and observed complication rates were similar to the new risk tool as opposed to the other risk calculators. Conclusions: The feasibility and usefulness of the MyIPOrisk-score have been demonstrated for the evaluation of patients undergoing digestive oncologic surgery. However, it requires further testing through a multicenter prospective study to validate the predictive accuracy of the proposed risk score.LAQV@REQUIMTEDQ - Departamento de QuímicaRUNFernandes, AnteroRodrigues, JéssicaAntunes, LuísLages, PatríciaSantos, Carla SaloméMoreira-Gonçalves, DanielCosta, Rafael S.Sousa, Joaquim AbreuDinis-Ribeiro, MárioSantos, Lúcio Lara2021-03-29T22:23:51Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/114683eng2047-0525PURE: 26039137https://doi.org/10.1186/s13741-020-00151-7info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T17:51:32Zoai:run.unl.pt:10362/114683Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:22:40.234317Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Development of a preoperative risk score on admission in surgical intermediate care unit in gastrointestinal cancer surgery
title Development of a preoperative risk score on admission in surgical intermediate care unit in gastrointestinal cancer surgery
spellingShingle Development of a preoperative risk score on admission in surgical intermediate care unit in gastrointestinal cancer surgery
Fernandes, Antero
SDG 3 - Good Health and Well-being
title_short Development of a preoperative risk score on admission in surgical intermediate care unit in gastrointestinal cancer surgery
title_full Development of a preoperative risk score on admission in surgical intermediate care unit in gastrointestinal cancer surgery
title_fullStr Development of a preoperative risk score on admission in surgical intermediate care unit in gastrointestinal cancer surgery
title_full_unstemmed Development of a preoperative risk score on admission in surgical intermediate care unit in gastrointestinal cancer surgery
title_sort Development of a preoperative risk score on admission in surgical intermediate care unit in gastrointestinal cancer surgery
author Fernandes, Antero
author_facet Fernandes, Antero
Rodrigues, Jéssica
Antunes, Luís
Lages, Patrícia
Santos, Carla Salomé
Moreira-Gonçalves, Daniel
Costa, Rafael S.
Sousa, Joaquim Abreu
Dinis-Ribeiro, Mário
Santos, Lúcio Lara
author_role author
author2 Rodrigues, Jéssica
Antunes, Luís
Lages, Patrícia
Santos, Carla Salomé
Moreira-Gonçalves, Daniel
Costa, Rafael S.
Sousa, Joaquim Abreu
Dinis-Ribeiro, Mário
Santos, Lúcio Lara
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv LAQV@REQUIMTE
DQ - Departamento de Química
RUN
dc.contributor.author.fl_str_mv Fernandes, Antero
Rodrigues, Jéssica
Antunes, Luís
Lages, Patrícia
Santos, Carla Salomé
Moreira-Gonçalves, Daniel
Costa, Rafael S.
Sousa, Joaquim Abreu
Dinis-Ribeiro, Mário
Santos, Lúcio Lara
dc.subject.por.fl_str_mv SDG 3 - Good Health and Well-being
topic SDG 3 - Good Health and Well-being
description DSAIPA/DS/0042/2018 UID/DTP/00617/2019
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
2021-03-29T22:23:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/114683
url http://hdl.handle.net/10362/114683
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2047-0525
PURE: 26039137
https://doi.org/10.1186/s13741-020-00151-7
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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