Synthetic biology to engineer bacteriophage genomes
Main Author: | |
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Publication Date: | 2024 |
Other Authors: | , |
Language: | eng |
Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
Download full: | https://hdl.handle.net/1822/91497 |
Summary: | Recent advances in the synthetic biology field have enabled the development of new molecular biology techniques used to build specialized bacteriophages with new functionalities. Bacteriophages have been engineered toward a wide range of applications, including pathogen control and detection, targeted drug delivery, or even assembly of new materials. In this chapter, two strategies that have been successfully used to genetically engineer bacteriophage genomes will be addressed: the bacteriophage recombineering of electroporated DNA (BRED) and the yeast-based phage-engineering platform. |
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Synthetic biology to engineer bacteriophage genomesBacteriophageBacteriophage engineeringYACBREDRecent advances in the synthetic biology field have enabled the development of new molecular biology techniques used to build specialized bacteriophages with new functionalities. Bacteriophages have been engineered toward a wide range of applications, including pathogen control and detection, targeted drug delivery, or even assembly of new materials. In this chapter, two strategies that have been successfully used to genetically engineer bacteriophage genomes will be addressed: the bacteriophage recombineering of electroporated DNA (BRED) and the yeast-based phage-engineering platform.FCT -Fundação para a Ciência e a Tecnologia(EXPL/EMD-EMD/1142/2021)info:eu-repo/semantics/publishedVersionSpringerUniversidade do MinhoCosta, Ana RitaAzeredo, JoanaPires, Diana Priscila Penso20242024-01-01T00:00:00Zbook partinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/1822/91497engCosta, Ana Rita; Azeredo, Joana; Pires, Diana P., Synthetic biology to engineer bacteriophage genomes. In Azeredo, J., Sillankorva, S. (eds), Bacteriophage Therapy: From Lab to Clinical Practice (2nd edition), New York: Springer, 2024. ISBN: 978-1-0716-3522-3, 261-277978-1-0716-3522-31064-374510.1007/978-1-0716-3523-0_1738066375https://doi.org/10.1007/978-1-0716-3523-0_9info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-12-14T01:18:19Zoai:repositorium.sdum.uminho.pt:1822/91497Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:52:18.044588Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
dc.title.none.fl_str_mv |
Synthetic biology to engineer bacteriophage genomes |
title |
Synthetic biology to engineer bacteriophage genomes |
spellingShingle |
Synthetic biology to engineer bacteriophage genomes Costa, Ana Rita Bacteriophage Bacteriophage engineering YAC BRED |
title_short |
Synthetic biology to engineer bacteriophage genomes |
title_full |
Synthetic biology to engineer bacteriophage genomes |
title_fullStr |
Synthetic biology to engineer bacteriophage genomes |
title_full_unstemmed |
Synthetic biology to engineer bacteriophage genomes |
title_sort |
Synthetic biology to engineer bacteriophage genomes |
author |
Costa, Ana Rita |
author_facet |
Costa, Ana Rita Azeredo, Joana Pires, Diana Priscila Penso |
author_role |
author |
author2 |
Azeredo, Joana Pires, Diana Priscila Penso |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Costa, Ana Rita Azeredo, Joana Pires, Diana Priscila Penso |
dc.subject.por.fl_str_mv |
Bacteriophage Bacteriophage engineering YAC BRED |
topic |
Bacteriophage Bacteriophage engineering YAC BRED |
description |
Recent advances in the synthetic biology field have enabled the development of new molecular biology techniques used to build specialized bacteriophages with new functionalities. Bacteriophages have been engineered toward a wide range of applications, including pathogen control and detection, targeted drug delivery, or even assembly of new materials. In this chapter, two strategies that have been successfully used to genetically engineer bacteriophage genomes will be addressed: the bacteriophage recombineering of electroporated DNA (BRED) and the yeast-based phage-engineering platform. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024 2024-01-01T00:00:00Z |
dc.type.driver.fl_str_mv |
book part |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/1822/91497 |
url |
https://hdl.handle.net/1822/91497 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Costa, Ana Rita; Azeredo, Joana; Pires, Diana P., Synthetic biology to engineer bacteriophage genomes. In Azeredo, J., Sillankorva, S. (eds), Bacteriophage Therapy: From Lab to Clinical Practice (2nd edition), New York: Springer, 2024. ISBN: 978-1-0716-3522-3, 261-277 978-1-0716-3522-3 1064-3745 10.1007/978-1-0716-3523-0_17 38066375 https://doi.org/10.1007/978-1-0716-3523-0_9 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Springer |
publisher.none.fl_str_mv |
Springer |
dc.source.none.fl_str_mv |
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Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia |
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