Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab Countries
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Outros |
| Idioma: | eng |
| Título da fonte: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
| Texto Completo: | http://hdl.handle.net/10362/157762 |
Resumo: | Funding Information: This work is supported by the College of Medicine and Health Sciences (CMHS) of the United Arab Emirates University (UAEU) research grant [Grant number: G00003625]. The contribution of MSS and KRM was supported by the United Arab Emirates University PhD grant and the Stipendium Hungaricum Scholarship Programme, respectively. Publisher Copyright: © 2023 by the authors. |
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Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab CountriesA Systematic Review and Meta-AnalysisagricultureArab countriesDNA damagegenotoxicityoccupational exposurepesticideToxicologyHealth, Toxicology and MutagenesisChemical Health and SafetySDG 3 - Good Health and Well-beingFunding Information: This work is supported by the College of Medicine and Health Sciences (CMHS) of the United Arab Emirates University (UAEU) research grant [Grant number: G00003625]. The contribution of MSS and KRM was supported by the United Arab Emirates University PhD grant and the Stipendium Hungaricum Scholarship Programme, respectively. Publisher Copyright: © 2023 by the authors.Exposure to pesticides in Arab countries is a significant public health concern due to extensive agricultural activity and pesticide use. This systematic review aimed to evaluate the genotoxic effects of agricultural pesticide exposure in the region, identify research gaps, and assess methodological limitations. Following the PRISMA guidelines, a comprehensive search yielded five relevant studies conducted in Egypt, Syria, and Jordan. Various genotoxicity assays were employed, revealing a higher level of DNA damage in exposed compared to non-exposed individuals. Farmers exposed to pesticides exhibited a significantly higher occurrence of chromosomal translocation (t(14;18)), micronuclei, and chromosomal aberrations. However, only two studies assessed cytotoxicity indirectly. The studies predominantly focused on male participants, with variations in sample size and pesticide types. The lack of detailed exposure data necessitates cautious interpretation. This review underscores the need for further research on the genotoxicity of occupational pesticide exposure in the Middle East. Future studies should adopt robust study designs, collect biological and environmental samples, conduct repeated sampling, analyze seasonal variations, and encompass diverse study sites associated with specific crop groups.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Comprehensive Health Research Centre (CHRC) - pólo NMSRUNSherif, MoustafaMakame, Khadija RamadhanÖstlundh, LindaPaulo, Marilia SilvaNemmar, AbderrahimAli, Bassam R.Al-Rifai, Rami H.Nagy, KárolyÁdám, Balázs2023-09-13T22:18:13Z2023-082023-08-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttp://hdl.handle.net/10362/157762eng2305-6304PURE: 71088083https://doi.org/10.3390/toxics11080663info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T18:14:21Zoai:run.unl.pt:10362/157762Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:44:58.484229Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
| dc.title.none.fl_str_mv |
Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab Countries A Systematic Review and Meta-Analysis |
| title |
Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab Countries |
| spellingShingle |
Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab Countries Sherif, Moustafa agriculture Arab countries DNA damage genotoxicity occupational exposure pesticide Toxicology Health, Toxicology and Mutagenesis Chemical Health and Safety SDG 3 - Good Health and Well-being |
| title_short |
Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab Countries |
| title_full |
Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab Countries |
| title_fullStr |
Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab Countries |
| title_full_unstemmed |
Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab Countries |
| title_sort |
Genotoxicity of Occupational Pesticide Exposures among Agricultural Workers in Arab Countries |
| author |
Sherif, Moustafa |
| author_facet |
Sherif, Moustafa Makame, Khadija Ramadhan Östlundh, Linda Paulo, Marilia Silva Nemmar, Abderrahim Ali, Bassam R. Al-Rifai, Rami H. Nagy, Károly Ádám, Balázs |
| author_role |
author |
| author2 |
Makame, Khadija Ramadhan Östlundh, Linda Paulo, Marilia Silva Nemmar, Abderrahim Ali, Bassam R. Al-Rifai, Rami H. Nagy, Károly Ádám, Balázs |
| author2_role |
author author author author author author author author |
| dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) Comprehensive Health Research Centre (CHRC) - pólo NMS RUN |
| dc.contributor.author.fl_str_mv |
Sherif, Moustafa Makame, Khadija Ramadhan Östlundh, Linda Paulo, Marilia Silva Nemmar, Abderrahim Ali, Bassam R. Al-Rifai, Rami H. Nagy, Károly Ádám, Balázs |
| dc.subject.por.fl_str_mv |
agriculture Arab countries DNA damage genotoxicity occupational exposure pesticide Toxicology Health, Toxicology and Mutagenesis Chemical Health and Safety SDG 3 - Good Health and Well-being |
| topic |
agriculture Arab countries DNA damage genotoxicity occupational exposure pesticide Toxicology Health, Toxicology and Mutagenesis Chemical Health and Safety SDG 3 - Good Health and Well-being |
| description |
Funding Information: This work is supported by the College of Medicine and Health Sciences (CMHS) of the United Arab Emirates University (UAEU) research grant [Grant number: G00003625]. The contribution of MSS and KRM was supported by the United Arab Emirates University PhD grant and the Stipendium Hungaricum Scholarship Programme, respectively. Publisher Copyright: © 2023 by the authors. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023-09-13T22:18:13Z 2023-08 2023-08-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/other |
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other |
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publishedVersion |
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http://hdl.handle.net/10362/157762 |
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http://hdl.handle.net/10362/157762 |
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eng |
| language |
eng |
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2305-6304 PURE: 71088083 https://doi.org/10.3390/toxics11080663 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia instacron:RCAAP |
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Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
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Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
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Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia |
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info@rcaap.pt |
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