Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose

Bibliographic Details
Main Author: Eça, Rosário
Publication Date: 2023
Other Authors: Ferreira, Sofia, Gandara, Judit, Pessegueiro Miranda, Helena, Daniel, Jorge
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10400.16/2948
Summary: The majority of acute iron toxicity cases occur in young children from accidental ingestion. In adults, iron poisoning is rare and mostly due to intentional ingestion. Physicians, particularly those who do not routinely treat pediatric patients, are often unfamiliar with the clinical manifestation of iron poisoning, its management, and its potential for multiple organ failure, especially liver damage. Severe acute hepatotoxicity treated with liver transplantation is rare in adults, with very limited published literature. We report a case of a severe iron tablet overdose with suicidal intent that progressed to fulminant hepatic failure despite medical treatment, ultimately treated with liver transplantation.
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spelling Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdoseacute liver failurehepatotoxicityiron intoxicationliver transplantsuicide attemptThe majority of acute iron toxicity cases occur in young children from accidental ingestion. In adults, iron poisoning is rare and mostly due to intentional ingestion. Physicians, particularly those who do not routinely treat pediatric patients, are often unfamiliar with the clinical manifestation of iron poisoning, its management, and its potential for multiple organ failure, especially liver damage. Severe acute hepatotoxicity treated with liver transplantation is rare in adults, with very limited published literature. We report a case of a severe iron tablet overdose with suicidal intent that progressed to fulminant hepatic failure despite medical treatment, ultimately treated with liver transplantation.Cureus, Inc.Repositório Científico da Unidade Local de Saúde de Santo AntónioEça, RosárioFerreira, SofiaGandara, JuditPessegueiro Miranda, HelenaDaniel, Jorge2024-06-18T09:25:30Z2023-112023-11-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.16/2948eng2168-818410.7759/cureus.48392info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2025-02-26T10:08:22Zoai:repositorio.chporto.pt:10400.16/2948Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T21:19:59.827451Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose
title Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose
spellingShingle Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose
Eça, Rosário
acute liver failure
hepatotoxicity
iron intoxication
liver transplant
suicide attempt
title_short Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose
title_full Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose
title_fullStr Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose
title_full_unstemmed Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose
title_sort Liver Transplantation for Acute Hepatic Failure Following Intentional Iron Overdose
author Eça, Rosário
author_facet Eça, Rosário
Ferreira, Sofia
Gandara, Judit
Pessegueiro Miranda, Helena
Daniel, Jorge
author_role author
author2 Ferreira, Sofia
Gandara, Judit
Pessegueiro Miranda, Helena
Daniel, Jorge
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico da Unidade Local de Saúde de Santo António
dc.contributor.author.fl_str_mv Eça, Rosário
Ferreira, Sofia
Gandara, Judit
Pessegueiro Miranda, Helena
Daniel, Jorge
dc.subject.por.fl_str_mv acute liver failure
hepatotoxicity
iron intoxication
liver transplant
suicide attempt
topic acute liver failure
hepatotoxicity
iron intoxication
liver transplant
suicide attempt
description The majority of acute iron toxicity cases occur in young children from accidental ingestion. In adults, iron poisoning is rare and mostly due to intentional ingestion. Physicians, particularly those who do not routinely treat pediatric patients, are often unfamiliar with the clinical manifestation of iron poisoning, its management, and its potential for multiple organ failure, especially liver damage. Severe acute hepatotoxicity treated with liver transplantation is rare in adults, with very limited published literature. We report a case of a severe iron tablet overdose with suicidal intent that progressed to fulminant hepatic failure despite medical treatment, ultimately treated with liver transplantation.
publishDate 2023
dc.date.none.fl_str_mv 2023-11
2023-11-01T00:00:00Z
2024-06-18T09:25:30Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.16/2948
url http://hdl.handle.net/10400.16/2948
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2168-8184
10.7759/cureus.48392
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Cureus, Inc.
publisher.none.fl_str_mv Cureus, Inc.
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron_str RCAAP
institution RCAAP
reponame_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
collection Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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