Hormone replacement therapy - The controversy

Detalhes bibliográficos
Autor(a) principal: Prata, Leonor
Data de Publicação: 2003
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Texto Completo: https://doi.org/10.32385/rpmgf.v19i4.9960
Resumo: A Hormone Replacement Therapy (HRT) with estrogen alone, or in combination with progestin, was, until recently, a preferred therapeutic in the prevention and treatment of many of the problems of climacteric. He got up, still, the hope of its effects in primary and even secondary cardiovascular disease. Recent studies have, however, lead to a more cautious, the use of these drugs. These suggest an increased risk of cardiovascular and breast cancer in women using HRT. These studies show, however, some limitations as important by many authors. On the other hand, increases the risk encountered, were smaller. Based on current knowledge, therefore continues to recommend itself, a careful evaluation of the risks and benefits of HRT for each woman, a sharing of decisions between doctor and patient and an annual reassessment of the situation. Should not be forgotten the alternatives therapeutic effects are well documented, such as aspirin, statins and control of hypertension, cardiovascular risk reduction, bisphosphonates, and others in the treatment of osteoporosis and other for other health problems climacteric.
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spelling Hormone replacement therapy - The controversyTerapêutica hormonal de substituição - A controvérsiaMenopausaClimatérioEstrogéniosProgestagéniosDoença CardiovascularOsteoporoseNeoplasia da MamaMenopauseestrogensprogestogensCardiovascular DiseaseOsteoporosisBreast NeoplasiaA Hormone Replacement Therapy (HRT) with estrogen alone, or in combination with progestin, was, until recently, a preferred therapeutic in the prevention and treatment of many of the problems of climacteric. He got up, still, the hope of its effects in primary and even secondary cardiovascular disease. Recent studies have, however, lead to a more cautious, the use of these drugs. These suggest an increased risk of cardiovascular and breast cancer in women using HRT. These studies show, however, some limitations as important by many authors. On the other hand, increases the risk encountered, were smaller. Based on current knowledge, therefore continues to recommend itself, a careful evaluation of the risks and benefits of HRT for each woman, a sharing of decisions between doctor and patient and an annual reassessment of the situation. Should not be forgotten the alternatives therapeutic effects are well documented, such as aspirin, statins and control of hypertension, cardiovascular risk reduction, bisphosphonates, and others in the treatment of osteoporosis and other for other health problems climacteric.A Terapêutica Hormonal de Substituição (THS), com estrogénios isolados, ou em associação com progestagénio, constituía, até há pouco tempo, uma terapêutica preferencial na prevenção e tratamento de muitos dos problemas do climatério. Levantava-se, ainda, a esperança dos seus efeitos na prevenção primária e, mesmo, secundária, da doença cardiovascular. Estudos recentes vieram, no entanto, levar a uma posição mais cautelosa, na utilização destes fármacos. Estes sugerem um aumento do risco cardiovascular e de cancro da mama, nas mulheres submetidas a THS. Estes estudos apresentam, no entanto, algumas limitações, consideradas importantes por muitos autores. Por outro lado, os aumentos de risco encontrados, foram pequenos. No estado actual dos conhecimentos, continua, assim, a recomendar-se, uma avaliação criteriosa dos riscos e benefícios da THS para cada mulher, uma partilha de decisões entre médico e paciente e uma reavaliação anual da situação. Não devem ser esquecidas as alternativas terapêuticas, de efeitos bem documentados, como a aspirina, as estatinas e o controle da hipertensão, na redução do risco cardiovascular, os bifosfonatos, e outros, no tratamento da osteoporose e outras, para os outros problemas de saúde no climatério.Associação Portuguesa de Medicina Geral e Familiar2003-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.32385/rpmgf.v19i4.9960https://doi.org/10.32385/rpmgf.v19i4.9960Portuguese Journal of Family Medicine and General Practice; Vol. 19 No. 4 (2003): Revista Portuguesa de Clínica Geral; 379-85Revista Portuguesa de Medicina Geral e Familiar; Vol. 19 Núm. 4 (2003): Revista Portuguesa de Clínica Geral; 379-85Revista Portuguesa de Medicina Geral e Familiar; Vol. 19 N.º 4 (2003): Revista Portuguesa de Clínica Geral; 379-852182-51812182-517310.32385/rpmgf.v19i4reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAPporhttps://rpmgf.pt/ojs/index.php/rpmgf/article/view/9960https://rpmgf.pt/ojs/index.php/rpmgf/article/view/9960/9698Prata, Leonorinfo:eu-repo/semantics/openAccess2024-09-17T11:58:21Zoai:ojs.rpmgf.pt:article/9960Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T18:50:34.453594Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Hormone replacement therapy - The controversy
Terapêutica hormonal de substituição - A controvérsia
title Hormone replacement therapy - The controversy
spellingShingle Hormone replacement therapy - The controversy
Prata, Leonor
Menopausa
Climatério
Estrogénios
Progestagénios
Doença Cardiovascular
Osteoporose
Neoplasia da Mama
Menopause
estrogens
progestogens
Cardiovascular Disease
Osteoporosis
Breast Neoplasia
title_short Hormone replacement therapy - The controversy
title_full Hormone replacement therapy - The controversy
title_fullStr Hormone replacement therapy - The controversy
title_full_unstemmed Hormone replacement therapy - The controversy
title_sort Hormone replacement therapy - The controversy
author Prata, Leonor
author_facet Prata, Leonor
author_role author
dc.contributor.author.fl_str_mv Prata, Leonor
dc.subject.por.fl_str_mv Menopausa
Climatério
Estrogénios
Progestagénios
Doença Cardiovascular
Osteoporose
Neoplasia da Mama
Menopause
estrogens
progestogens
Cardiovascular Disease
Osteoporosis
Breast Neoplasia
topic Menopausa
Climatério
Estrogénios
Progestagénios
Doença Cardiovascular
Osteoporose
Neoplasia da Mama
Menopause
estrogens
progestogens
Cardiovascular Disease
Osteoporosis
Breast Neoplasia
description A Hormone Replacement Therapy (HRT) with estrogen alone, or in combination with progestin, was, until recently, a preferred therapeutic in the prevention and treatment of many of the problems of climacteric. He got up, still, the hope of its effects in primary and even secondary cardiovascular disease. Recent studies have, however, lead to a more cautious, the use of these drugs. These suggest an increased risk of cardiovascular and breast cancer in women using HRT. These studies show, however, some limitations as important by many authors. On the other hand, increases the risk encountered, were smaller. Based on current knowledge, therefore continues to recommend itself, a careful evaluation of the risks and benefits of HRT for each woman, a sharing of decisions between doctor and patient and an annual reassessment of the situation. Should not be forgotten the alternatives therapeutic effects are well documented, such as aspirin, statins and control of hypertension, cardiovascular risk reduction, bisphosphonates, and others in the treatment of osteoporosis and other for other health problems climacteric.
publishDate 2003
dc.date.none.fl_str_mv 2003-07-01
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dc.publisher.none.fl_str_mv Associação Portuguesa de Medicina Geral e Familiar
publisher.none.fl_str_mv Associação Portuguesa de Medicina Geral e Familiar
dc.source.none.fl_str_mv Portuguese Journal of Family Medicine and General Practice; Vol. 19 No. 4 (2003): Revista Portuguesa de Clínica Geral; 379-85
Revista Portuguesa de Medicina Geral e Familiar; Vol. 19 Núm. 4 (2003): Revista Portuguesa de Clínica Geral; 379-85
Revista Portuguesa de Medicina Geral e Familiar; Vol. 19 N.º 4 (2003): Revista Portuguesa de Clínica Geral; 379-85
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