Renal failure and pleural effusion; a diagnostic challenge

Bibliographic Details
Main Author: Fernandes, Sara Cardoso
Publication Date: 2023
Other Authors: Marques, Joana, Pinto, Mário, Góis, Mário, Sousa, Helena, Nolasco, Fernando
Format: Article
Language: eng
Source: Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
Download full: http://hdl.handle.net/10362/158322
Summary: Publisher Copyright: © 2023 The Author(s); Published by Society of Diabetic Nephropathy Prevention.
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network_name_str Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
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spelling Renal failure and pleural effusion; a diagnostic challengeAA amyloidosisPleural amyloidosisRenal amyloidosisSjögren’s syndromeNephrologyPublisher Copyright: © 2023 The Author(s); Published by Society of Diabetic Nephropathy Prevention.Sjögren’s syndrome is a chronic inflammatory disorder mostly involving the exocrine glands. Extraglandular disease may occur in up to one quarter of patients. Kidney involvement is rare, more often manifested by tubular dysfunction secondary to tubulointerstitial nephritis. Primary glomerular disease is uncommon. The authors present the case of a 73-year-old woman with xerostomia and positivity for anti-Ro and anti-La antibodies admitted for acute kidney injury and exudative pleural effusion. Biopsy of salivary glands was compatible with Sjögren’s syndrome. Extraglandular involvement was also confirmed by renal and pleural deposition of AA-amyloid. The patient was started on prednisolone followed by azathioprine with rapid improvement of lung disease. However, due to progressing renal disease and clinical deterioration, prognosis was guarded and the patient died. We describe a case of secondary amyloidosis with systemic involvement and infrequent clinical manifestations, briefly reviewing the key aspects of Sjögren’s syndrome and AA-amyloidosis.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNFernandes, Sara CardosoMarques, JoanaPinto, MárioGóis, MárioSousa, HelenaNolasco, Fernando2023-09-26T22:20:22Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/158322eng2251-8363PURE: 72194797https://doi.org/10.34172/jnp.2023.17309info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-05-22T18:14:39Zoai:run.unl.pt:10362/158322Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T17:45:12.599870Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse
dc.title.none.fl_str_mv Renal failure and pleural effusion; a diagnostic challenge
title Renal failure and pleural effusion; a diagnostic challenge
spellingShingle Renal failure and pleural effusion; a diagnostic challenge
Fernandes, Sara Cardoso
AA amyloidosis
Pleural amyloidosis
Renal amyloidosis
Sjögren’s syndrome
Nephrology
title_short Renal failure and pleural effusion; a diagnostic challenge
title_full Renal failure and pleural effusion; a diagnostic challenge
title_fullStr Renal failure and pleural effusion; a diagnostic challenge
title_full_unstemmed Renal failure and pleural effusion; a diagnostic challenge
title_sort Renal failure and pleural effusion; a diagnostic challenge
author Fernandes, Sara Cardoso
author_facet Fernandes, Sara Cardoso
Marques, Joana
Pinto, Mário
Góis, Mário
Sousa, Helena
Nolasco, Fernando
author_role author
author2 Marques, Joana
Pinto, Mário
Góis, Mário
Sousa, Helena
Nolasco, Fernando
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Fernandes, Sara Cardoso
Marques, Joana
Pinto, Mário
Góis, Mário
Sousa, Helena
Nolasco, Fernando
dc.subject.por.fl_str_mv AA amyloidosis
Pleural amyloidosis
Renal amyloidosis
Sjögren’s syndrome
Nephrology
topic AA amyloidosis
Pleural amyloidosis
Renal amyloidosis
Sjögren’s syndrome
Nephrology
description Publisher Copyright: © 2023 The Author(s); Published by Society of Diabetic Nephropathy Prevention.
publishDate 2023
dc.date.none.fl_str_mv 2023-09-26T22:20:22Z
2023
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/158322
url http://hdl.handle.net/10362/158322
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2251-8363
PURE: 72194797
https://doi.org/10.34172/jnp.2023.17309
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)
instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
instacron:RCAAP
instname_str FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
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repository.name.fl_str_mv Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologia
repository.mail.fl_str_mv info@rcaap.pt
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