Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in Portugal
| Main Author: | |
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| Publication Date: | 2024 |
| Other Authors: | , , , , |
| Format: | Article |
| Language: | eng |
| Source: | Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) |
| Download full: | http://hdl.handle.net/10362/172868 |
Summary: | Funding Information: This study was supported by European Funds through grant \u2018Bio-Molecular and Epidemiological Surveillance of HIV Transmitted Drug Resistance, Hepatitis Co-Infections and Ongoing Transmission Patterns in Europe\u2014BEST HOPE\u2014(project funded through HIVERA: Harmonizing Integrating Vitalizing European Research on HIV/Aids, grant 249697); by FCT for funds to GHTM-UID/Multi/04413/2013 and GHTM-UID/04413/2020; by the MigrantHIV project (financed by FCT: PTDC/DTP-EPI/7066/2014), by Characterization of drug-resistance TB and HIV, and associated socio-behavioral factors among migrants in Lisbon, Portugal project financed by Funda\u00E7\u00E3o para a Ci\u00EAncia e Tecnologia to GHTM-UID/04413/2020 and LA-REAL-LA/P/0117/2020.GHTM-UID/Multi/04413/2013 and by Integriv project (financed by FCT: PTDC/SAU-INF/31990/2017). Publisher Copyright: © 2024 by the authors. |
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Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in PortugalAre There Differences between Sexes?HIV-1migrantsnewly infected patientssexual risk behaviorSTIsImmunology and AllergyMolecular BiologyImmunology and Microbiology(all)Microbiology (medical)Infectious DiseasesSDG 3 - Good Health and Well-beingSDG 10 - Reduced InequalitiesFunding Information: This study was supported by European Funds through grant \u2018Bio-Molecular and Epidemiological Surveillance of HIV Transmitted Drug Resistance, Hepatitis Co-Infections and Ongoing Transmission Patterns in Europe\u2014BEST HOPE\u2014(project funded through HIVERA: Harmonizing Integrating Vitalizing European Research on HIV/Aids, grant 249697); by FCT for funds to GHTM-UID/Multi/04413/2013 and GHTM-UID/04413/2020; by the MigrantHIV project (financed by FCT: PTDC/DTP-EPI/7066/2014), by Characterization of drug-resistance TB and HIV, and associated socio-behavioral factors among migrants in Lisbon, Portugal project financed by Funda\u00E7\u00E3o para a Ci\u00EAncia e Tecnologia to GHTM-UID/04413/2020 and LA-REAL-LA/P/0117/2020.GHTM-UID/Multi/04413/2013 and by Integriv project (financed by FCT: PTDC/SAU-INF/31990/2017). Publisher Copyright: © 2024 by the authors.Introduction: Sexually transmitted infections (STIs) continue to occur at high levels. According to the WHO, each year there are an estimated 374 million new infections with syphilis, gonorrhea, chlamydia, and trichomoniasis. STIs are associated with an increased risk of acquiring HIV infection. Migrants are reportedly highly affected by STIs. Objectives: This study aims to characterize factors associated with STIs in a population of HIV-positive migrants living in Portugal. Methodology: This is a cross-sectional observational study of 265 newly diagnosed HIV-1 positive migrants, who were defined as individuals born outside Portugal. This group of people were part of the BESTHOPE study that was developed in 17 Portuguese hospitals between September 2014 and December 2019, and included information collected through sociodemographic and behavioral questionnaires filled in by the migrant patients, clinical questionnaires filled in by the clinicians and HIV-1 genomic sequences generated through resistance testing (Sanger sequencing). A multivariable statistical analysis was used to analyze the association between sociodemographic characteristics, sexual behaviors, HIV testing and sexual infections. Results: Most HIV-1 positive individuals included in the study were men (66.8%) and aged between 25 and 44 years old (59.9%). Men had a higher proportion of STIs when compared to women (40.4% vs. 14.0%) and the majority of men reported homosexual contacts (52.0%). Most men reported having had two or more occasional sexual partners in the previous year (88.8%) and 50.9% reported always using condoms with occasional partners, while 13.2% never used it. For regular partners, only 29.5% of the women reported using condoms, compared to 47.3% of men. Other risk behaviors for acquiring HIV, such as tattooing and performing invasive medical procedures, were more prevalent in men (38.0% and 46.2%, respectively), when compared to women (30.4% and 45.1% respectively) and 4.7% of men reported having already shared injectable materials, with no data for comparison in the case for women. Additionally, 23.9% of women reported having had a blood transfusion while only 10.3% of men reported having had this medical procedure. Meanwhile, 30.9% of the individuals reported having been diagnosed with some type of STI in the last 12 months. In addition, 43.3% of individuals that answered a question about hepatitis reported to be infected with hepatitis B, while 13.0% reported having hepatitis C infection. According to the multivariable analysis, the only transmission route was significantly associated with reports of previous STI infection: men who have sex with men (MSM) were 70% more likely to have been diagnosed with an STI in the past 12 months compared to the heterosexual route. Conclusion: HIV-1 infected men were more likely to report previous STIs than women. On the other hand, most migrant women had a regular sexual partner and never or only sometimes used condoms. This somewhat discrepant findings suggest that gender inequalities may make women unable to negotiate safe sexual practices, resulting in increased susceptibility to infection. However, since migrant women report less STIs, we cannot exclude that these STIs may remain undiagnosed. The implementation of safer sex awareness campaigns for condom use and screening for STIs in women is crucial. On the other hand, health education campaigns for STI knowledge need to be implemented for both MSM and women and their partners.TB, HIV and opportunistic diseases and pathogens (THOP)Global Health and Tropical Medicine (GHTM)Instituto de Higiene e Medicina Tropical (IHMT)Population health, policies and services (PPS)RUNthe BESTHOPE Study GroupMiranda, Mafalda N. S.Pimentel, VictorGraça, JacquelineSeabra, Sofia G.Sebastião, Cruz S.2024-10-02T22:22:22Z2024-072024-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/172868eng2076-0817PURE: 99500050https://doi.org/10.3390/pathogens13070598info:eu-repo/semantics/openAccessreponame:Repositórios Científicos de Acesso Aberto de Portugal (RCAAP)instname:FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiainstacron:RCAAP2024-10-07T01:40:36Zoai:run.unl.pt:10362/172868Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireinfo@rcaap.ptopendoar:https://opendoar.ac.uk/repository/71602025-05-28T18:55:25.374684Repositórios Científicos de Acesso Aberto de Portugal (RCAAP) - FCCN, serviços digitais da FCT – Fundação para a Ciência e a Tecnologiafalse |
| dc.title.none.fl_str_mv |
Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in Portugal Are There Differences between Sexes? |
| title |
Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in Portugal |
| spellingShingle |
Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in Portugal the BESTHOPE Study Group HIV-1 migrants newly infected patients sexual risk behavior STIs Immunology and Allergy Molecular Biology Immunology and Microbiology(all) Microbiology (medical) Infectious Diseases SDG 3 - Good Health and Well-being SDG 10 - Reduced Inequalities |
| title_short |
Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in Portugal |
| title_full |
Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in Portugal |
| title_fullStr |
Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in Portugal |
| title_full_unstemmed |
Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in Portugal |
| title_sort |
Sociodemographic, Clinical, and Behavioral Factors Associated with Sexual Transmitted Infection among HIV-1 Positive Migrants in Portugal |
| author |
the BESTHOPE Study Group |
| author_facet |
the BESTHOPE Study Group Miranda, Mafalda N. S. Pimentel, Victor Graça, Jacqueline Seabra, Sofia G. Sebastião, Cruz S. |
| author_role |
author |
| author2 |
Miranda, Mafalda N. S. Pimentel, Victor Graça, Jacqueline Seabra, Sofia G. Sebastião, Cruz S. |
| author2_role |
author author author author author |
| dc.contributor.none.fl_str_mv |
TB, HIV and opportunistic diseases and pathogens (THOP) Global Health and Tropical Medicine (GHTM) Instituto de Higiene e Medicina Tropical (IHMT) Population health, policies and services (PPS) RUN |
| dc.contributor.author.fl_str_mv |
the BESTHOPE Study Group Miranda, Mafalda N. S. Pimentel, Victor Graça, Jacqueline Seabra, Sofia G. Sebastião, Cruz S. |
| dc.subject.por.fl_str_mv |
HIV-1 migrants newly infected patients sexual risk behavior STIs Immunology and Allergy Molecular Biology Immunology and Microbiology(all) Microbiology (medical) Infectious Diseases SDG 3 - Good Health and Well-being SDG 10 - Reduced Inequalities |
| topic |
HIV-1 migrants newly infected patients sexual risk behavior STIs Immunology and Allergy Molecular Biology Immunology and Microbiology(all) Microbiology (medical) Infectious Diseases SDG 3 - Good Health and Well-being SDG 10 - Reduced Inequalities |
| description |
Funding Information: This study was supported by European Funds through grant \u2018Bio-Molecular and Epidemiological Surveillance of HIV Transmitted Drug Resistance, Hepatitis Co-Infections and Ongoing Transmission Patterns in Europe\u2014BEST HOPE\u2014(project funded through HIVERA: Harmonizing Integrating Vitalizing European Research on HIV/Aids, grant 249697); by FCT for funds to GHTM-UID/Multi/04413/2013 and GHTM-UID/04413/2020; by the MigrantHIV project (financed by FCT: PTDC/DTP-EPI/7066/2014), by Characterization of drug-resistance TB and HIV, and associated socio-behavioral factors among migrants in Lisbon, Portugal project financed by Funda\u00E7\u00E3o para a Ci\u00EAncia e Tecnologia to GHTM-UID/04413/2020 and LA-REAL-LA/P/0117/2020.GHTM-UID/Multi/04413/2013 and by Integriv project (financed by FCT: PTDC/SAU-INF/31990/2017). Publisher Copyright: © 2024 by the authors. |
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2024 |
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2024-10-02T22:22:22Z 2024-07 2024-07-01T00:00:00Z |
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info:eu-repo/semantics/publishedVersion |
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http://hdl.handle.net/10362/172868 |
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eng |
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eng |
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2076-0817 PURE: 99500050 https://doi.org/10.3390/pathogens13070598 |
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