Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial
| Main Author: | |
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| Publication Date: | 2016 |
| Other Authors: | , , , , , , , , , , , , , , , , |
| Language: | eng |
| Source: | Repositório Institucional da Escola Bahiana de Medicina e Saúde Pública |
| Download full: | http://www7.bahiana.edu.br//jspui/handle/bahiana/2958 |
Summary: | São Paulo |
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Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) TrialThe Annals of Thoracic SurgerySão Paulodial necrosis biomarkers and electrocardiographic abnormalities after revascularization procedures has resulted in a change in the myocardial infarction (MI) definition. Methods. Patients with stable multivessel disease who underwent percutaneous or surgical revascularization were included. Electrocardiograms and concentrations of high-sensitive cardiac troponin I (cTnI) and creatine kinase (CK)-MB were assessed before and after procedures. Cardiac magnetic resonance and late gadolinium enhancement were performed before and after procedures. MI was defined as more than five times the 99th percentile upper reference limit for cTnI and 10 times for CK-MB in percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG), respectively, and new late gadolinium enhancement for cardiac magnetic resonance. Results. Of the 202 patients studied, 69 (34.1%) underwent on-pump CABG, 67 (33.2%) off-pump CABG, and 66 (32.7%) PCI. The receiver operating characteristic curve showed the accuracy of cTnI for on-pump CABG, off-pump CABG, and PCI patients was 21.7%, 28.3%, and 52.4% and for CK-MB was 72.5%, 81.2%, and 90.5%, respectively. The specificity of cTnI was 3.6%, 9.4%, and 42.1% and of CK-MB was 73.2%, 86.8%, and 96.4%, respectively. Sensitivity of cTnI was 100%, 100%, and 100% and of CK-MB was 69.2%, 64.3%, and 44.4%, respectively. The best cutoff of cTnI for on-pump CABG, off-pump CABG, and PCI was 6.5 ng/mL, 4.5 ng/mL, and 4.5 ng/mL (162.5, 112.5, and 112.5 times the 99th percentile upper reference limit) and of CK-MB was 37.5 ng/mL, 22.5 ng/mL, and 11.5 ng/mL (8.5, 5.1, and 2.6 times the 99th percentile upper reference limit), respectively. Conclusions. Compared with cardiac magnetic resonance, CK-MB was more accurate than cTnI for diagnosing MI. These data suggest a higher troponin cutoff for the diagnosis of procedure-related MI.2019-06-25T19:16:35Z2019-06-25T19:16:35Z2016-06Produção bibliográfica: Artigos completos publicados em periódicosinfo:eu-repo/semantics/publishedVersionapplication/pdfVolume 101http://www7.bahiana.edu.br//jspui/handle/bahiana/2958https://www.annalsthoracicsurgery.org/article/S0003-4975(15)01883-4/fulltextreponame:Repositório Institucional da Escola Bahiana de Medicina e Saúde Públicainstname:Escola Bahiana de Medicina e Saúde Pública (EBM)instacron:EBMMelo, Rodrigo Morel Vieira deHueb, WhadyGersh, Bernard J.Costa, Leandro Menezes Alves daOikawa, Fernando Teiichi CostaRezende, Paulo CuryGarzillo, Cibele LarrosaLima, Eduardo GomesNomura, Cesar HigaVilla, Alexandre VolneyHueb, Alexandre CiappinaStrunz, Celia Maria CassaroFavarato, DesiderioTakiuti, Myrthes EmyAlbuquerque, Cicero Piva deSilva, Expedito Eustáquio Ribeiro daRamires, Jose Antonio FranchiniKalil Filho, Robertoenginfo:eu-repo/semantics/openAccess2025-07-25T21:14:13Zoai:repositorio.bahiana.edu.br:bahiana/2958Repositório InstitucionalPUBhttps://repositorio.bahiana.edu.br:8443/oai/requestrepositorio@bahiana.edu.br || ebmsp-bibliotecacp2@bahiana.edu.bropendoar:10.71.50.272025-07-25T21:14:13Repositório Institucional da Escola Bahiana de Medicina e Saúde Pública - Escola Bahiana de Medicina e Saúde Pública (EBM)false |
| dc.title.none.fl_str_mv |
Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial The Annals of Thoracic Surgery |
| title |
Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial |
| spellingShingle |
Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial Melo, Rodrigo Morel Vieira de |
| title_short |
Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial |
| title_full |
Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial |
| title_fullStr |
Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial |
| title_full_unstemmed |
Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial |
| title_sort |
Accuracy of Myocardial Biomarkers in the Diagnosis of Myocardial Infarction After Revascularization as Assessed by Cardiac Resonance: The Medicine, Angioplasty, Surgery Study V (MASS-V) Trial |
| author |
Melo, Rodrigo Morel Vieira de |
| author_facet |
Melo, Rodrigo Morel Vieira de Hueb, Whady Gersh, Bernard J. Costa, Leandro Menezes Alves da Oikawa, Fernando Teiichi Costa Rezende, Paulo Cury Garzillo, Cibele Larrosa Lima, Eduardo Gomes Nomura, Cesar Higa Villa, Alexandre Volney Hueb, Alexandre Ciappina Strunz, Celia Maria Cassaro Favarato, Desiderio Takiuti, Myrthes Emy Albuquerque, Cicero Piva de Silva, Expedito Eustáquio Ribeiro da Ramires, Jose Antonio Franchini Kalil Filho, Roberto |
| author_role |
author |
| author2 |
Hueb, Whady Gersh, Bernard J. Costa, Leandro Menezes Alves da Oikawa, Fernando Teiichi Costa Rezende, Paulo Cury Garzillo, Cibele Larrosa Lima, Eduardo Gomes Nomura, Cesar Higa Villa, Alexandre Volney Hueb, Alexandre Ciappina Strunz, Celia Maria Cassaro Favarato, Desiderio Takiuti, Myrthes Emy Albuquerque, Cicero Piva de Silva, Expedito Eustáquio Ribeiro da Ramires, Jose Antonio Franchini Kalil Filho, Roberto |
| author2_role |
author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Melo, Rodrigo Morel Vieira de Hueb, Whady Gersh, Bernard J. Costa, Leandro Menezes Alves da Oikawa, Fernando Teiichi Costa Rezende, Paulo Cury Garzillo, Cibele Larrosa Lima, Eduardo Gomes Nomura, Cesar Higa Villa, Alexandre Volney Hueb, Alexandre Ciappina Strunz, Celia Maria Cassaro Favarato, Desiderio Takiuti, Myrthes Emy Albuquerque, Cicero Piva de Silva, Expedito Eustáquio Ribeiro da Ramires, Jose Antonio Franchini Kalil Filho, Roberto |
| description |
São Paulo |
| publishDate |
2016 |
| dc.date.none.fl_str_mv |
2016-06 2019-06-25T19:16:35Z 2019-06-25T19:16:35Z |
| dc.type.driver.fl_str_mv |
Produção bibliográfica: Artigos completos publicados em periódicos |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
Volume 101 http://www7.bahiana.edu.br//jspui/handle/bahiana/2958 |
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Volume 101 |
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http://www7.bahiana.edu.br//jspui/handle/bahiana/2958 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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https://www.annalsthoracicsurgery.org/article/S0003-4975(15)01883-4/fulltext reponame:Repositório Institucional da Escola Bahiana de Medicina e Saúde Pública instname:Escola Bahiana de Medicina e Saúde Pública (EBM) instacron:EBM |
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Escola Bahiana de Medicina e Saúde Pública (EBM) |
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EBM |
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EBM |
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Repositório Institucional da Escola Bahiana de Medicina e Saúde Pública |
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Repositório Institucional da Escola Bahiana de Medicina e Saúde Pública |
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Repositório Institucional da Escola Bahiana de Medicina e Saúde Pública - Escola Bahiana de Medicina e Saúde Pública (EBM) |
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repositorio@bahiana.edu.br || ebmsp-bibliotecacp2@bahiana.edu.br |
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1843456561640374272 |