Neurological manifestations of coinfection with HIV and HTLV-1

Bibliographic Details
Main Author: Silva, Marcus T. T.
Publication Date: 2012
Other Authors: Neves, Elizabeth S., Grinsztejn, Beatriz, Espíndola, Otávio de Melo, Schor, Doris, Araujo, Abelardo
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1097/QAD.0b013e32835049be
Download full: https://arca.fiocruz.br/handle/icict/36375
Summary: 2020-10-11
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spelling Silva, Marcus T. T.Neves, Elizabeth S.Grinsztejn, BeatrizEspíndola, Otávio de MeloSchor, DorisAraujo, Abelardo2019-10-11T11:59:15Z2019-10-11T11:59:15Z2012SILVA, Marcus T. T. et al. Neurological manifestations of coinfection with HIV and human T-lymphotropic virus type 1. AIDS, v. 26, n. 4, p. 521-523, 2012.0269-9370https://arca.fiocruz.br/handle/icict/3637510.1097/QAD.0b013e32835049be1473-5571engLippincott, Williams & WilkinsNeurological manifestations of coinfection with HIV and HTLV-1info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-10-11Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Neuroinfecção. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Neuroinfecção. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em Patogenia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa em Patogenia Viral. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Pesquisa Clínica em Neuroinfecção. Rio de Janeiro, RJ, Brasil.HIV-individuals are at risk for human T-lymphotropic virus (HTLV) coinfection and neurological diseases. Little is known about the impact of HAART among coinfected patients. In this study, 47 out of 428 HIV individuals were coinfected with HTLV (10.9%). Coinfection was an independent variable associated with neurological outcome (odds ratio 8.73). Coinfection was associated with myelopathy [chi square (X2 ) U 93, P< 0.001], peripheral neuropathy (X2 U 6.5, P U 0.01), and hepatitis C virus infection (X2 U 36.5, P< 0.001). HAART did not appear to protect against neurological diseases and had no impact on HTLV proviral load.HIVHTLV-1Neurological manifestationsCoinfectioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://arca.fiocruz.br/bitstreams/7d48fed6-fe18-4d8c-aa67-71ae768e7874/download8a4605be74aa9ea9d79846c1fba20a33MD51falseAnonymousREADORIGINALve_Silva_Marcus_etal_INI_2012.pdfve_Silva_Marcus_etal_INI_2012.pdfapplication/pdf197676https://arca.fiocruz.br/bitstreams/f87989fe-8d6d-4370-b0e5-ae8aaf7a7aa3/downloada13cc021eb7310755424f8835866c8ceMD52trueAnonymousREAD2020-10-11TEXTve_Silva_Marcus_etal_INI_2012.pdf.txtve_Silva_Marcus_etal_INI_2012.pdf.txtExtracted texttext/plain29822https://arca.fiocruz.br/bitstreams/9f4925e9-aa36-4a60-a6ca-c3ec58924177/download3f78f519144efbf3f4db0e9d01b2e92cMD57falseAnonymousREAD2020-10-11THUMBNAILve_Silva_Marcus_etal_INI_2012.pdf.jpgve_Silva_Marcus_etal_INI_2012.pdf.jpgGenerated Thumbnailimage/jpeg6133https://arca.fiocruz.br/bitstreams/6f501bb2-68f3-4734-8bbf-c632f586c7a8/download38418e1ba59675fdf12d0a4bf665a8feMD58falseAnonymousREAD2020-10-11icict/363752025-07-29 19:24:31.958open.accessoai:arca.fiocruz.br:icict/36375https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-07-29T22:24:31Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)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
dc.title.none.fl_str_mv Neurological manifestations of coinfection with HIV and HTLV-1
title Neurological manifestations of coinfection with HIV and HTLV-1
spellingShingle Neurological manifestations of coinfection with HIV and HTLV-1
Silva, Marcus T. T.
HIV
HTLV-1
Neurological manifestations
Coinfection
title_short Neurological manifestations of coinfection with HIV and HTLV-1
title_full Neurological manifestations of coinfection with HIV and HTLV-1
title_fullStr Neurological manifestations of coinfection with HIV and HTLV-1
title_full_unstemmed Neurological manifestations of coinfection with HIV and HTLV-1
title_sort Neurological manifestations of coinfection with HIV and HTLV-1
author Silva, Marcus T. T.
author_facet Silva, Marcus T. T.
Neves, Elizabeth S.
Grinsztejn, Beatriz
Espíndola, Otávio de Melo
Schor, Doris
Araujo, Abelardo
author_role author
author2 Neves, Elizabeth S.
Grinsztejn, Beatriz
Espíndola, Otávio de Melo
Schor, Doris
Araujo, Abelardo
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Marcus T. T.
Neves, Elizabeth S.
Grinsztejn, Beatriz
Espíndola, Otávio de Melo
Schor, Doris
Araujo, Abelardo
dc.subject.en.none.fl_str_mv HIV
HTLV-1
Neurological manifestations
Coinfection
topic HIV
HTLV-1
Neurological manifestations
Coinfection
description 2020-10-11
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2019-10-11T11:59:15Z
dc.date.available.fl_str_mv 2019-10-11T11:59:15Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, Marcus T. T. et al. Neurological manifestations of coinfection with HIV and human T-lymphotropic virus type 1. AIDS, v. 26, n. 4, p. 521-523, 2012.
dc.identifier.uri.fl_str_mv https://arca.fiocruz.br/handle/icict/36375
dc.identifier.issn.none.fl_str_mv 0269-9370
dc.identifier.doi.none.fl_str_mv 10.1097/QAD.0b013e32835049be
dc.identifier.eissn.none.fl_str_mv 1473-5571
identifier_str_mv SILVA, Marcus T. T. et al. Neurological manifestations of coinfection with HIV and human T-lymphotropic virus type 1. AIDS, v. 26, n. 4, p. 521-523, 2012.
0269-9370
10.1097/QAD.0b013e32835049be
1473-5571
url https://arca.fiocruz.br/handle/icict/36375
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Lippincott, Williams & Wilkins
publisher.none.fl_str_mv Lippincott, Williams & Wilkins
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
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collection Repositório Institucional da FIOCRUZ (ARCA)
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