Mitochondria push platelets past their prime
| Main Author: | |
|---|---|
| Publication Date: | 2008 |
| Other Authors: | |
| Format: | Article |
| Language: | eng |
| Source: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.1182/blood-2007-12-126193 |
| Download full: | https://arca.fiocruz.br/handle/icict/57570 |
Summary: | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil. |
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Bozza, Fernando A.Weyrich, Andrew S.2023-03-25T00:08:47Z2023-03-25T00:08:47Z2008BOZZA, Fernando A.; WEYRICH, Andrew S. Mitochondria push platelets past their prime. Blood, Philadelphia, v. 111, n. 5, p. 2496-2497, Mar. 2008.0006-4971https://arca.fiocruz.br/handle/icict/5757010.1182/blood-2007-12-1261931528-0020engAmerican Society of HematologyMitochondria push platelets past their primeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.The University of Utah. UT, USA.In the February 1 issue of Blood, Jobe and colleagues elucidated the function of the mitochondrial permeability transition pore (MPTP), in platelet activation and demonstrated that cyclophilin D (CypD), a regulator of MPTP formation, is a critical factor in the procoagulant response to strong agonists.MitochondriaMitochondrial Permeability Transition Pore (MPTP)Demonstrated that Cyclophilin D (CypD)11 Cidades e comunidades sustentáveisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALBozza_Fernando_etal_INI_2008.pdfBozza_Fernando_etal_INI_2008.pdfapplication/pdf332416https://arca.fiocruz.br/bitstreams/cf82c303-481e-477f-bfc2-65d15f7c42dd/download5a06278979610b9720963d23e273423aMD52trueAnonymousREADLICENSElicense.txttext/plain1748https://arca.fiocruz.br/bitstreams/c1670875-4211-4afd-8792-405275179168/download8a4605be74aa9ea9d79846c1fba20a33MD51falseAnonymousREADTEXTBozza_Fernando_etal_INI_2008.pdf.txtBozza_Fernando_etal_INI_2008.pdf.txtExtracted texttext/plain11108https://arca.fiocruz.br/bitstreams/c78bc1ce-8b8a-4d0a-80f7-bbd774e46f22/downloadc0e7895f25de8a8fc21f6f82235fc36bMD55falseAnonymousREADTHUMBNAILBozza_Fernando_etal_INI_2008.pdf.jpgBozza_Fernando_etal_INI_2008.pdf.jpgGenerated Thumbnailimage/jpeg6046https://arca.fiocruz.br/bitstreams/606f0e7d-f41e-491a-934d-8b1950556a74/download586935a8c4fd421e443576843e6564b5MD56falseAnonymousREADicict/575702025-07-29 21:18:10.9open.accessoai:arca.fiocruz.br:icict/57570https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-07-30T00:18:10Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)falseTk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo= |
| dc.title.none.fl_str_mv |
Mitochondria push platelets past their prime |
| title |
Mitochondria push platelets past their prime |
| spellingShingle |
Mitochondria push platelets past their prime Bozza, Fernando A. Mitochondria Mitochondrial Permeability Transition Pore (MPTP) Demonstrated that Cyclophilin D (CypD) 11 Cidades e comunidades sustentáveis |
| title_short |
Mitochondria push platelets past their prime |
| title_full |
Mitochondria push platelets past their prime |
| title_fullStr |
Mitochondria push platelets past their prime |
| title_full_unstemmed |
Mitochondria push platelets past their prime |
| title_sort |
Mitochondria push platelets past their prime |
| author |
Bozza, Fernando A. |
| author_facet |
Bozza, Fernando A. Weyrich, Andrew S. |
| author_role |
author |
| author2 |
Weyrich, Andrew S. |
| author2_role |
author |
| dc.contributor.author.fl_str_mv |
Bozza, Fernando A. Weyrich, Andrew S. |
| dc.subject.en.none.fl_str_mv |
Mitochondria Mitochondrial Permeability Transition Pore (MPTP) Demonstrated that Cyclophilin D (CypD) |
| topic |
Mitochondria Mitochondrial Permeability Transition Pore (MPTP) Demonstrated that Cyclophilin D (CypD) 11 Cidades e comunidades sustentáveis |
| dc.subject.ods.none.fl_str_mv |
11 Cidades e comunidades sustentáveis |
| description |
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil. |
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2008 |
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2008 |
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2023-03-25T00:08:47Z |
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2023-03-25T00:08:47Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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BOZZA, Fernando A.; WEYRICH, Andrew S. Mitochondria push platelets past their prime. Blood, Philadelphia, v. 111, n. 5, p. 2496-2497, Mar. 2008. |
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https://arca.fiocruz.br/handle/icict/57570 |
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0006-4971 |
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10.1182/blood-2007-12-126193 |
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1528-0020 |
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BOZZA, Fernando A.; WEYRICH, Andrew S. Mitochondria push platelets past their prime. Blood, Philadelphia, v. 111, n. 5, p. 2496-2497, Mar. 2008. 0006-4971 10.1182/blood-2007-12-126193 1528-0020 |
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American Society of Hematology |
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American Society of Hematology |
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