Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings

Bibliographic Details
Main Author: Torres, Thiago S.
Publication Date: 2018
Other Authors: Harrison, Linda J., la Rosa, Alberto M., Lavenberg, Jeffrey A., Zheng, Lu, Safren, Steven A., Ngongondo, Mcneil, Poongulali, Selvamuthu, Matoga, Mitch, Samaneka, Wadzanai, Collier, Ann C., Hughes, Michael D.
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1080/09540121.2018.1427207
Download full: https://arca.fiocruz.br/handle/icict/28807
Summary: Center for Biostatistics in AIDS Research. Harvard T. H. Chan School of Public Health. Boston, MA, USA / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.
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spelling Torres, Thiago S.Harrison, Linda J.la Rosa, Alberto M.Lavenberg, Jeffrey A.Zheng, LuSafren, Steven A.Ngongondo, McneilPoongulali, SelvamuthuMatoga, MitchSamaneka, WadzanaiCollier, Ann C.Hughes, Michael D.2018-09-14T18:23:12Z2018-09-14T18:23:12Z2018TORRES, Thiago S. et al. Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings. Aids Care, v. 30, n. 8, p. 954-962, Aug. 2017.0954-0121https://arca.fiocruz.br/handle/icict/2880710.1080/09540121.2018.1427207engQuality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settingsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCenter for Biostatistics in AIDS Research. Harvard T. H. Chan School of Public Health. Boston, MA, USA / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Center for Biostatistics in AIDS Research. Harvard T. H. Chan School of Public Health. Boston, MA, USA.Asociación Civil Impacta Salud y Educación. Lima, Peru.Center for Biostatistics in AIDS Research. Harvard T. H. Chan School of Public Health. Boston, MA, USA.Center for Biostatistics in AIDS Research. Harvard T. H. Chan School of Public Health. Boston, MA, USA.Department of Psychology. University of Miami. Miami, FL, USA.Center for Biostatistics in AIDS Research. Harvard T. H. Chan School of Public Health. Boston, MA, USA / UNC Project Lilongwe. Lilongwe, Malaw.YRGCARE Medical Centre. VHS. Chennai, India.UNC Project Lilongwe. Lilongwe, Malawi.Department of Medicine. University of Zimbabwe-University of California Collaborative Research Programme, Harare, Zimbabwe.Department of Medicine. University of Washington. Seattle, WA, USA.Center for Biostatistics in AIDS Research. Harvard T. H. Chan School of Public Health. Boston, MA, USA.We evaluated health-related quality of life (QoL) in HIV infection participants with virologic failure (VF) on first-line antiretroviral therapy (ART) in 9 resource-limited settings (RLS). ACTG SF-21 was completed by 512 participants at A5273 study entry; 8 domains assessed: general health perceptions (GHP), physical functioning (PF), role functioning (RF), social functioning (SF), cognitive functioning (CF), pain (P), mental health (MH), and energy/fatigue (E/F); each was scored between 0 (worst) to 100 (best). Mean QoL scores ranged from 67 (GHP) to 91 (PF, SF, CF). QoL varied by country; high VL and low CD4 were associated with worse QoL in most domains, except RF (VL only), SF (CD4 only) and CF (neither). Number of comorbidities, BMI and history of AIDS were associated with some domains. Relationships between QoL and VL varied among countries for all domains. The association of worse disease status with worse QoL may reflect low QoL when ART was initiated and/or deterioration associated with VF.Health-related quality of lifeHIVVirologic failureAntiretroviral TherapyResource-limited settingsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83099https://arca.fiocruz.br/bitstreams/7f1bca56-4978-47b0-b899-a33098c4ce08/download586c046dcfeef936e32f0323bb9a47c0MD51falseAnonymousREADORIGINALQuality of life among HIV infected individuals_Thiago_Torres_INI_Lapclin-AIDS_2018.pdfQuality of life among HIV infected individuals_Thiago_Torres_INI_Lapclin-AIDS_2018.pdfapplication/pdf1248317https://arca.fiocruz.br/bitstreams/4626f7e6-d38b-4dbc-b33f-74538eb4bcaa/download796961560c2e090a094dc540ae28026fMD52trueAnonymousREAD2020-08-06TEXTQuality of life among HIV infected individuals_Thiago_Torres_INI_Lapclin-AIDS_2018.pdf.txtQuality of life among HIV infected individuals_Thiago_Torres_INI_Lapclin-AIDS_2018.pdf.txtExtracted texttext/plain45606https://arca.fiocruz.br/bitstreams/4539749b-1a00-438f-a8ae-6ab32dbe07a5/download0beb095b5d485d7dc5d96cb3caae1940MD55falseAnonymousREAD2020-08-06THUMBNAILQuality of life among HIV infected individuals_Thiago_Torres_INI_Lapclin-AIDS_2018.pdf.jpgQuality of life among HIV infected individuals_Thiago_Torres_INI_Lapclin-AIDS_2018.pdf.jpgGenerated Thumbnailimage/jpeg4573https://arca.fiocruz.br/bitstreams/c2ee547c-5dbd-4b51-aee9-2370497b65c7/downloadd75bcd74eb09ee83bce937a60d153733MD56falseAnonymousREAD2020-08-06icict/288072025-07-30 02:02:01.184open.accessoai:arca.fiocruz.br:icict/28807https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-07-30T05:02:01Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.none.fl_str_mv Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings
title Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings
spellingShingle Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings
Torres, Thiago S.
Health-related quality of life
HIV
Virologic failure
Antiretroviral Therapy
Resource-limited settings
title_short Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings
title_full Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings
title_fullStr Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings
title_full_unstemmed Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings
title_sort Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings
author Torres, Thiago S.
author_facet Torres, Thiago S.
Harrison, Linda J.
la Rosa, Alberto M.
Lavenberg, Jeffrey A.
Zheng, Lu
Safren, Steven A.
Ngongondo, Mcneil
Poongulali, Selvamuthu
Matoga, Mitch
Samaneka, Wadzanai
Collier, Ann C.
Hughes, Michael D.
author_role author
author2 Harrison, Linda J.
la Rosa, Alberto M.
Lavenberg, Jeffrey A.
Zheng, Lu
Safren, Steven A.
Ngongondo, Mcneil
Poongulali, Selvamuthu
Matoga, Mitch
Samaneka, Wadzanai
Collier, Ann C.
Hughes, Michael D.
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Torres, Thiago S.
Harrison, Linda J.
la Rosa, Alberto M.
Lavenberg, Jeffrey A.
Zheng, Lu
Safren, Steven A.
Ngongondo, Mcneil
Poongulali, Selvamuthu
Matoga, Mitch
Samaneka, Wadzanai
Collier, Ann C.
Hughes, Michael D.
dc.subject.en.none.fl_str_mv Health-related quality of life
HIV
Virologic failure
Antiretroviral Therapy
Resource-limited settings
topic Health-related quality of life
HIV
Virologic failure
Antiretroviral Therapy
Resource-limited settings
description Center for Biostatistics in AIDS Research. Harvard T. H. Chan School of Public Health. Boston, MA, USA / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-09-14T18:23:12Z
dc.date.available.fl_str_mv 2018-09-14T18:23:12Z
dc.date.issued.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TORRES, Thiago S. et al. Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings. Aids Care, v. 30, n. 8, p. 954-962, Aug. 2017.
dc.identifier.uri.fl_str_mv https://arca.fiocruz.br/handle/icict/28807
dc.identifier.issn.none.fl_str_mv 0954-0121
dc.identifier.doi.none.fl_str_mv 10.1080/09540121.2018.1427207
identifier_str_mv TORRES, Thiago S. et al. Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings. Aids Care, v. 30, n. 8, p. 954-962, Aug. 2017.
0954-0121
10.1080/09540121.2018.1427207
url https://arca.fiocruz.br/handle/icict/28807
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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