The effect of the essential oils from five different Lippia species on the viability of tumor cell lines

Bibliographic Details
Main Author: Gomide, Mayna da Silveira
Publication Date: 2013
Other Authors: Lemos, Fernanda de Oliveira, Lopes, Miriam Tereza Paz, Alves, Tânia Maria de Almeida, Viccini, Lyderson Facio, Coelho, Cíntia Marques
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1590/S0102-695X2013000600006
Download full: https://arca.fiocruz.br/handle/icict/29018
Summary: Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Biologia. Juiz de Fora, MG, Brazil.
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spelling Gomide, Mayna da SilveiraLemos, Fernanda de OliveiraLopes, Miriam Tereza PazAlves, Tânia Maria de AlmeidaViccini, Lyderson FacioCoelho, Cíntia Marques2018-09-24T18:09:03Z2018-09-24T18:09:03Z2013GOMIDE, Mayna da Silveira et al. The effect of the essential oils from five different Lippia species on the viability of tumor cell lines. Revista Brasileira de Farmacognosia, v. 23, n. 6, p. 895-902, Nov./Dec. 2013.0102-695Xhttps://arca.fiocruz.br/handle/icict/2901810.1590/S0102-695X2013000600006engSociedade Brasileira de FarmacognosiaCitotoxicidadeÓleos essenciaisLippiaTerpenosCytotoxicityEssential oilLippiaTerpenesThe effect of the essential oils from five different Lippia species on the viability of tumor cell linesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Biologia. Juiz de Fora, MG, Brazil.Instituto de Ciências Biológicas. Departamento de Farmacologia. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil.Instituto de Ciências Biológicas. Departamento de Farmacologia. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Química de Produtos Naturais. Belo Horizonte, MG, Brazil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Biologia. Juiz de Fora, MG, Brazil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Biologia. Juiz de Fora, MG, Brazil.Several Lippia species have been used in folk medicine mainly for gastrointestinal and respiratory diseases. Their biological properties have been partially associated to the terpenoids found in their essential oils. According to the World Health Organization, cancer is the leading cause of death worldwide and is described as a complex group of diseases with several hallmarks. One of its acceptable defining features is the cell proliferation beyond their boundaries forming the tumors. Importantly, some drugs currently available were discovered by the investigation of plant secondary metabolites. Thus, this study aimed to evaluate in vitro cytotoxic effect of the essential oils extracted from five Lippia species against tumor cell lines. The results indicated that mouse colon carcinoma CT26.WT cell line viability was significantly reduced showing an IC50 of 19.05, 30.20 and 36.30 µg/ml when treated with the essential oils of L. sidoides, L. salviifolia and L. rotundifolia, respectively. Human lung carcinoma A549 cell line also had a compromised viability to the action of L. alba carvone chemotype essential oil. The tested essential oils did not compromise viability of the normal cell line CHO. These finds suggest that the studied Lippia essential oils might be good candidates for further in-depth studies.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://arca.fiocruz.br/bitstreams/de85fd6e-1afc-4cdd-917a-273d1d8e913e/download9193a7c197bc67acd023525e72a03240MD51falseAnonymousREADORIGINALThe effect of the essential oils from five different.pdfThe effect of the essential oils from five different.pdfapplication/pdf2890704https://arca.fiocruz.br/bitstreams/6e3250e1-7e8c-4e34-bca9-1a9c525b8875/download9ca0c5e61cbbe0d23d497009a9dc149eMD52trueAnonymousREADTEXTThe effect of the essential oils from five different.pdf.txtThe effect of the essential oils from five different.pdf.txtExtracted texttext/plain267https://arca.fiocruz.br/bitstreams/e114aae2-a9d3-4d7b-be47-d42aa01fbaf5/downloade98ea0e7e7b94e5fc371e83a718596faMD57falseAnonymousREADTHUMBNAILThe effect of the essential oils from five different.pdf.jpgThe effect of the essential oils from five different.pdf.jpgGenerated Thumbnailimage/jpeg4917https://arca.fiocruz.br/bitstreams/d545294e-e65c-4500-8884-add877d60e57/downloadfdd11c8d91196ca1bd8700b97a955962MD58falseAnonymousREADicict/290182025-07-29 18:36:52.035open.accessoai:arca.fiocruz.br:icict/29018https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-07-29T21:36:52Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.none.fl_str_mv The effect of the essential oils from five different Lippia species on the viability of tumor cell lines
title The effect of the essential oils from five different Lippia species on the viability of tumor cell lines
spellingShingle The effect of the essential oils from five different Lippia species on the viability of tumor cell lines
Gomide, Mayna da Silveira
Citotoxicidade
Óleos essenciais
Lippia
Terpenos
Cytotoxicity
Essential oil
Lippia
Terpenes
title_short The effect of the essential oils from five different Lippia species on the viability of tumor cell lines
title_full The effect of the essential oils from five different Lippia species on the viability of tumor cell lines
title_fullStr The effect of the essential oils from five different Lippia species on the viability of tumor cell lines
title_full_unstemmed The effect of the essential oils from five different Lippia species on the viability of tumor cell lines
title_sort The effect of the essential oils from five different Lippia species on the viability of tumor cell lines
author Gomide, Mayna da Silveira
author_facet Gomide, Mayna da Silveira
Lemos, Fernanda de Oliveira
Lopes, Miriam Tereza Paz
Alves, Tânia Maria de Almeida
Viccini, Lyderson Facio
Coelho, Cíntia Marques
author_role author
author2 Lemos, Fernanda de Oliveira
Lopes, Miriam Tereza Paz
Alves, Tânia Maria de Almeida
Viccini, Lyderson Facio
Coelho, Cíntia Marques
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Gomide, Mayna da Silveira
Lemos, Fernanda de Oliveira
Lopes, Miriam Tereza Paz
Alves, Tânia Maria de Almeida
Viccini, Lyderson Facio
Coelho, Cíntia Marques
dc.subject.other.none.fl_str_mv Citotoxicidade
Óleos essenciais
Lippia
Terpenos
topic Citotoxicidade
Óleos essenciais
Lippia
Terpenos
Cytotoxicity
Essential oil
Lippia
Terpenes
dc.subject.en.none.fl_str_mv Cytotoxicity
Essential oil
Lippia
Terpenes
description Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Biologia. Juiz de Fora, MG, Brazil.
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2018-09-24T18:09:03Z
dc.date.available.fl_str_mv 2018-09-24T18:09:03Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GOMIDE, Mayna da Silveira et al. The effect of the essential oils from five different Lippia species on the viability of tumor cell lines. Revista Brasileira de Farmacognosia, v. 23, n. 6, p. 895-902, Nov./Dec. 2013.
dc.identifier.uri.fl_str_mv https://arca.fiocruz.br/handle/icict/29018
dc.identifier.issn.none.fl_str_mv 0102-695X
dc.identifier.doi.none.fl_str_mv 10.1590/S0102-695X2013000600006
identifier_str_mv GOMIDE, Mayna da Silveira et al. The effect of the essential oils from five different Lippia species on the viability of tumor cell lines. Revista Brasileira de Farmacognosia, v. 23, n. 6, p. 895-902, Nov./Dec. 2013.
0102-695X
10.1590/S0102-695X2013000600006
url https://arca.fiocruz.br/handle/icict/29018
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
publisher.none.fl_str_mv Sociedade Brasileira de Farmacognosia
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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