The effect of the essential oils from five different Lippia species on the viability of tumor cell lines
| Main Author: | |
|---|---|
| Publication Date: | 2013 |
| Other Authors: | , , , , |
| Format: | Article |
| Language: | eng |
| Source: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.1590/S0102-695X2013000600006 |
| Download full: | https://arca.fiocruz.br/handle/icict/29018 |
Summary: | Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Biologia. Juiz de Fora, MG, Brazil. |
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Gomide, Mayna da SilveiraLemos, Fernanda de OliveiraLopes, Miriam Tereza PazAlves, Tânia Maria de AlmeidaViccini, Lyderson FacioCoelho, Cíntia Marques2018-09-24T18:09:03Z2018-09-24T18:09:03Z2013GOMIDE, Mayna da Silveira et al. The effect of the essential oils from five different Lippia species on the viability of tumor cell lines. Revista Brasileira de Farmacognosia, v. 23, n. 6, p. 895-902, Nov./Dec. 2013.0102-695Xhttps://arca.fiocruz.br/handle/icict/2901810.1590/S0102-695X2013000600006engSociedade Brasileira de FarmacognosiaCitotoxicidadeÓleos essenciaisLippiaTerpenosCytotoxicityEssential oilLippiaTerpenesThe effect of the essential oils from five different Lippia species on the viability of tumor cell linesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Biologia. Juiz de Fora, MG, Brazil.Instituto de Ciências Biológicas. Departamento de Farmacologia. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil.Instituto de Ciências Biológicas. Departamento de Farmacologia. Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Química de Produtos Naturais. Belo Horizonte, MG, Brazil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Biologia. Juiz de Fora, MG, Brazil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Biologia. Juiz de Fora, MG, Brazil.Several Lippia species have been used in folk medicine mainly for gastrointestinal and respiratory diseases. Their biological properties have been partially associated to the terpenoids found in their essential oils. According to the World Health Organization, cancer is the leading cause of death worldwide and is described as a complex group of diseases with several hallmarks. One of its acceptable defining features is the cell proliferation beyond their boundaries forming the tumors. Importantly, some drugs currently available were discovered by the investigation of plant secondary metabolites. Thus, this study aimed to evaluate in vitro cytotoxic effect of the essential oils extracted from five Lippia species against tumor cell lines. The results indicated that mouse colon carcinoma CT26.WT cell line viability was significantly reduced showing an IC50 of 19.05, 30.20 and 36.30 µg/ml when treated with the essential oils of L. sidoides, L. salviifolia and L. rotundifolia, respectively. Human lung carcinoma A549 cell line also had a compromised viability to the action of L. alba carvone chemotype essential oil. The tested essential oils did not compromise viability of the normal cell line CHO. These finds suggest that the studied Lippia essential oils might be good candidates for further in-depth studies.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://arca.fiocruz.br/bitstreams/de85fd6e-1afc-4cdd-917a-273d1d8e913e/download9193a7c197bc67acd023525e72a03240MD51falseAnonymousREADORIGINALThe effect of the essential oils from five different.pdfThe effect of the essential oils from five different.pdfapplication/pdf2890704https://arca.fiocruz.br/bitstreams/6e3250e1-7e8c-4e34-bca9-1a9c525b8875/download9ca0c5e61cbbe0d23d497009a9dc149eMD52trueAnonymousREADTEXTThe effect of the essential oils from five different.pdf.txtThe effect of the essential oils from five different.pdf.txtExtracted texttext/plain267https://arca.fiocruz.br/bitstreams/e114aae2-a9d3-4d7b-be47-d42aa01fbaf5/downloade98ea0e7e7b94e5fc371e83a718596faMD57falseAnonymousREADTHUMBNAILThe effect of the essential oils from five different.pdf.jpgThe effect of the essential oils from five different.pdf.jpgGenerated Thumbnailimage/jpeg4917https://arca.fiocruz.br/bitstreams/d545294e-e65c-4500-8884-add877d60e57/downloadfdd11c8d91196ca1bd8700b97a955962MD58falseAnonymousREADicict/290182025-07-29 18:36:52.035open.accessoai:arca.fiocruz.br:icict/29018https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-07-29T21:36:52Repositório Institucional da FIOCRUZ (ARCA) - 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| dc.title.none.fl_str_mv |
The effect of the essential oils from five different Lippia species on the viability of tumor cell lines |
| title |
The effect of the essential oils from five different Lippia species on the viability of tumor cell lines |
| spellingShingle |
The effect of the essential oils from five different Lippia species on the viability of tumor cell lines Gomide, Mayna da Silveira Citotoxicidade Óleos essenciais Lippia Terpenos Cytotoxicity Essential oil Lippia Terpenes |
| title_short |
The effect of the essential oils from five different Lippia species on the viability of tumor cell lines |
| title_full |
The effect of the essential oils from five different Lippia species on the viability of tumor cell lines |
| title_fullStr |
The effect of the essential oils from five different Lippia species on the viability of tumor cell lines |
| title_full_unstemmed |
The effect of the essential oils from five different Lippia species on the viability of tumor cell lines |
| title_sort |
The effect of the essential oils from five different Lippia species on the viability of tumor cell lines |
| author |
Gomide, Mayna da Silveira |
| author_facet |
Gomide, Mayna da Silveira Lemos, Fernanda de Oliveira Lopes, Miriam Tereza Paz Alves, Tânia Maria de Almeida Viccini, Lyderson Facio Coelho, Cíntia Marques |
| author_role |
author |
| author2 |
Lemos, Fernanda de Oliveira Lopes, Miriam Tereza Paz Alves, Tânia Maria de Almeida Viccini, Lyderson Facio Coelho, Cíntia Marques |
| author2_role |
author author author author author |
| dc.contributor.author.fl_str_mv |
Gomide, Mayna da Silveira Lemos, Fernanda de Oliveira Lopes, Miriam Tereza Paz Alves, Tânia Maria de Almeida Viccini, Lyderson Facio Coelho, Cíntia Marques |
| dc.subject.other.none.fl_str_mv |
Citotoxicidade Óleos essenciais Lippia Terpenos |
| topic |
Citotoxicidade Óleos essenciais Lippia Terpenos Cytotoxicity Essential oil Lippia Terpenes |
| dc.subject.en.none.fl_str_mv |
Cytotoxicity Essential oil Lippia Terpenes |
| description |
Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Biologia. Juiz de Fora, MG, Brazil. |
| publishDate |
2013 |
| dc.date.issued.fl_str_mv |
2013 |
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2018-09-24T18:09:03Z |
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2018-09-24T18:09:03Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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GOMIDE, Mayna da Silveira et al. The effect of the essential oils from five different Lippia species on the viability of tumor cell lines. Revista Brasileira de Farmacognosia, v. 23, n. 6, p. 895-902, Nov./Dec. 2013. |
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https://arca.fiocruz.br/handle/icict/29018 |
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0102-695X |
| dc.identifier.doi.none.fl_str_mv |
10.1590/S0102-695X2013000600006 |
| identifier_str_mv |
GOMIDE, Mayna da Silveira et al. The effect of the essential oils from five different Lippia species on the viability of tumor cell lines. Revista Brasileira de Farmacognosia, v. 23, n. 6, p. 895-902, Nov./Dec. 2013. 0102-695X 10.1590/S0102-695X2013000600006 |
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Sociedade Brasileira de Farmacognosia |
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Sociedade Brasileira de Farmacognosia |
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