Development of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil

Bibliographic Details
Main Author: Ramesh, Anita
Publication Date: 2018
Other Authors: Cameron, Mary, Spence, Kirstin, Hoek Spaans, Remy, Melo-Santos, Maria A. V., Paiva, Marcelo H. S., Guedes, Duschinka R. D., Barbosa, Rosangela M. R., Oliveira, Claudia M. F., Sá, André, Jeffries, Claire L., Castanha, Priscila M. S., Oliveira, Paula A. S., Walker, Thomas, Alexander, Neal, Braga, Cynthia
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1371/journal.pntd.0006816
Download full: https://arca.fiocruz.br/handle/icict/32360
Summary: Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Parasitologia. Recife, PE, Brasil / London School of Hygiene & Tropical Medicine (LSHTM). Department of Infectious Disease Epidemiology. London, United Kingdom.
id CRUZ_248b2fc19c511b86c5a47c4f3bc020fa
oai_identifier_str oai:arca.fiocruz.br:icict/32360
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Ramesh, AnitaCameron, MarySpence, KirstinHoek Spaans, RemyMelo-Santos, Maria A. V.Paiva, Marcelo H. S.Guedes, Duschinka R. D.Barbosa, Rosangela M. R.Oliveira, Claudia M. F.Sá, AndréJeffries, Claire L.Castanha, Priscila M. S.Oliveira, Paula A. S.Walker, ThomasAlexander, NealBraga, Cynthia2019-04-04T13:47:11Z2019-04-04T13:47:11Z2018RAMESH, A. et al. Development of an Urban Molecular Xenomonitoring System for Lymphatic Filariasis in the Recife Metropolitan Region, Brazil. PLoS Neglected Tropical Diseases, v. 12, n. 10, p. 1-24, 2018.1935-2735https://arca.fiocruz.br/handle/icict/3236010.1371/journal.pntd.0006816engDevelopment of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Parasitologia. Recife, PE, Brasil / London School of Hygiene & Tropical Medicine (LSHTM). Department of Infectious Disease Epidemiology. London, United Kingdom.LSHTM. Department of Disease Control. London, United Kingdom.LSHTM. Department of Disease Control. London, United Kingdom.LSHTM. Department of Disease Control. London, United Kingdom.LSHTM. Department of Disease Control. London, United Kingdom.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Entomologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Entomologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Entomologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Entomologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Entomologia. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Centro de Geoprocessamento e Estatística. Recife, PE, Brasil.LSHTM. Department of Disease Control. London, United Kingdom.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Virologia. Recife, PE, Brasil / Universidade de Pernambuco. Faculdade de Ciências Médicas. Instituto Biológico de Medicina. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Parasitologia. Recife, PE, Brasil.LSHTM. Department of Disease Control. London, United Kingdom.London School of Hygiene & Tropical Medicine (LSHTM). Department of Infectious Disease Epidemiology. London, United Kingdom.Introduction: Molecular xenomonitoring (MX)—pathogen detection in the mosquito rather than human— is a promising tool for lymphatic filariasis (LF) surveillance. In the Recife Metropolitan Region (RMR), the last LF focus in Brazil, Culex quinquefasciatus mosquitoes have been implicated in transmitting Wuchereria bancrofti parasites. This paper presents findings on the ideal mosquito collection method, mosquito dispersion, W. bancrofti infection in mosquitoes and W. bancrofti antigen in humans to aid MX development. Methods: Experiments occurred within two densely populated urban areas of Olinda, RMR, in July and August 2015. U.S. Centers for Disease Control and Prevention (CDC) light traps were compared to battery-powered aspirators as collection methods, and mosquito dispersion was measured by mosquito mark release recapture (MMRR). Female Cx. quinquefasciatus were tested by PCR for W. bancrofti infection, and study area residents were screened by rapid tests for W. bancrofti antigen. Results: Aspirators caught 2.6 times more total Cx. quinquefasciatus, including 38 times more bloodfed and 5 times more gravid stages, than CDC light traps. They also collected 123 times more Aedes aegypti. Of the 9,644 marked mosquitoes released, only ten (0.01%) were recaptured, nine of which were < 50m (34.8m median, 85.4m maximum) from the release point. Of 9,169 unmarked mosquitoes captured in the MMR, 38.3% were unfed, 48.8% blood-fed, 5.5% semi-gravid, and 7.3% gravid. PCR on 182 pools (1,556 mosquitoes) found no evidence of W. bancrofti infection in Cx. quinquefasciatus. Rapid tests on 110 of 111 eligible residents were all negative for W. bancrofti antigen. Conclusions: Aspirators were more effective than CDC light traps at capturing Ae. aegypti and all but unfed stages of Cx. quinquefasciatus. Female Cx. quinquefasciatus traveled short (< 86m) distances in this urban area. Lack of evidence for W. bancrofti infection in mosquitoes and antigen in humans in these fine-scale studies does not indicate that LF transmission has ceased in the RMR. A MX surveillance system should consider vector-specific collection methods, mosquito dispersion, and spatial scale but also local context, environmental factors such as sanitation, and host factors such as infection prevalence and treatment history.AdultAedes/growth & developmentAedes/parasitologyAgedAnimalsAntigens, Protozoan/bloodBrazil/epidemiologyCross-Over StudiesCulex/growth & developmentDisease Transmission, InfectiousElephantiasis, Filarial/epidemiologyCulex/parasitologyEntomology/methodsEpidemiological MonitoringFemaleHumansImmunoassayMaleMiddle AgedPolymerase Chain ReactionPrevalenceUrban PopulationWuchereria bancrofti/geneticsAdultoAedes / crescimento e desenvolvimentoAedes / parasitologiaEnvelhecidoIdoso, 80 anos ou maisAnimaisAntígenos, Protozoários / sangueBrasilEstudos Cross-OverCulex / crescimento e desenvolvimentoCulex / parasitologiaTransmissão de Doenças InfecciosasFilariose Linfática / epidemiologiaEntomologia / métodosMonitorização EpidemiológicaFêmeaHumanosImunoensaioMasculinoMeia idadeReação em Cadeia da PolimerasePrevalênciaPopulação urbanaWuchereria bancrofti / genéticaWuchereria bancrofti / isolamento e purificação05 Igualdade de gênero11 Cidades e comunidades sustentáveisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83094https://arca.fiocruz.br/bitstreams/4fdf029f-c279-44c8-a373-126d2a91522e/downloadee3692f7b0b97d5638099ab94397d05fMD51falseAnonymousREADORIGINALDevelopment of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil.pdfDevelopment of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil.pdfapplication/pdf2805328https://arca.fiocruz.br/bitstreams/7cfadda5-7c75-4e42-9594-e603ee371db9/downloade56c3d921c9426abaedddd1b78e740f0MD52trueAnonymousREADTEXTDevelopment of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil.pdf.txtDevelopment of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil.pdf.txtExtracted texttext/plain92391https://arca.fiocruz.br/bitstreams/159fd451-fc27-4bc2-adab-a0c0ad40a76e/download7712d822c19f9f07f189e085a8f42e91MD57falseAnonymousREADTHUMBNAILDevelopment of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil.pdf.jpgDevelopment of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil.pdf.jpgGenerated Thumbnailimage/jpeg5886https://arca.fiocruz.br/bitstreams/73e2812d-5270-44fb-8e28-b968cb3d2ea6/download0dfb8be7e633b4502abeb3e7d0c328b8MD58falseAnonymousREADicict/323602025-07-29 18:20:49.946open.accessoai:arca.fiocruz.br:icict/32360https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-07-29T21:20:49Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)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
dc.title.none.fl_str_mv Development of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil
title Development of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil
spellingShingle Development of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil
Ramesh, Anita
Adult
Aedes/growth & development
Aedes/parasitology
Aged
Animals
Antigens, Protozoan/blood
Brazil/epidemiology
Cross-Over Studies
Culex/growth & development
Disease Transmission, Infectious
Elephantiasis, Filarial/epidemiology
Culex/parasitology
Entomology/methods
Epidemiological Monitoring
Female
Humans
Immunoassay
Male
Middle Aged
Polymerase Chain Reaction
Prevalence
Urban Population
Wuchereria bancrofti/genetics
Adulto
Aedes / crescimento e desenvolvimento
Aedes / parasitologia
Envelhecido
Idoso, 80 anos ou mais
Animais
Antígenos, Protozoários / sangue
Brasil
Estudos Cross-Over
Culex / crescimento e desenvolvimento
Culex / parasitologia
Transmissão de Doenças Infecciosas
Filariose Linfática / epidemiologia
Entomologia / métodos
Monitorização Epidemiológica
Fêmea
Humanos
Imunoensaio
Masculino
Meia idade
Reação em Cadeia da Polimerase
Prevalência
População urbana
Wuchereria bancrofti / genética
Wuchereria bancrofti / isolamento e purificação
05 Igualdade de gênero
11 Cidades e comunidades sustentáveis
title_short Development of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil
title_full Development of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil
title_fullStr Development of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil
title_full_unstemmed Development of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil
title_sort Development of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil
author Ramesh, Anita
author_facet Ramesh, Anita
Cameron, Mary
Spence, Kirstin
Hoek Spaans, Remy
Melo-Santos, Maria A. V.
Paiva, Marcelo H. S.
Guedes, Duschinka R. D.
Barbosa, Rosangela M. R.
Oliveira, Claudia M. F.
Sá, André
Jeffries, Claire L.
Castanha, Priscila M. S.
Oliveira, Paula A. S.
Walker, Thomas
Alexander, Neal
Braga, Cynthia
author_role author
author2 Cameron, Mary
Spence, Kirstin
Hoek Spaans, Remy
Melo-Santos, Maria A. V.
Paiva, Marcelo H. S.
Guedes, Duschinka R. D.
Barbosa, Rosangela M. R.
Oliveira, Claudia M. F.
Sá, André
Jeffries, Claire L.
Castanha, Priscila M. S.
Oliveira, Paula A. S.
Walker, Thomas
Alexander, Neal
Braga, Cynthia
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ramesh, Anita
Cameron, Mary
Spence, Kirstin
Hoek Spaans, Remy
Melo-Santos, Maria A. V.
Paiva, Marcelo H. S.
Guedes, Duschinka R. D.
Barbosa, Rosangela M. R.
Oliveira, Claudia M. F.
Sá, André
Jeffries, Claire L.
Castanha, Priscila M. S.
Oliveira, Paula A. S.
Walker, Thomas
Alexander, Neal
Braga, Cynthia
dc.subject.en.none.fl_str_mv Adult
Aedes/growth & development
Aedes/parasitology
Aged
Animals
Antigens, Protozoan/blood
Brazil/epidemiology
Cross-Over Studies
Culex/growth & development
Disease Transmission, Infectious
Elephantiasis, Filarial/epidemiology
Culex/parasitology
Entomology/methods
Epidemiological Monitoring
Female
Humans
Immunoassay
Male
Middle Aged
Polymerase Chain Reaction
Prevalence
Urban Population
Wuchereria bancrofti/genetics
topic Adult
Aedes/growth & development
Aedes/parasitology
Aged
Animals
Antigens, Protozoan/blood
Brazil/epidemiology
Cross-Over Studies
Culex/growth & development
Disease Transmission, Infectious
Elephantiasis, Filarial/epidemiology
Culex/parasitology
Entomology/methods
Epidemiological Monitoring
Female
Humans
Immunoassay
Male
Middle Aged
Polymerase Chain Reaction
Prevalence
Urban Population
Wuchereria bancrofti/genetics
Adulto
Aedes / crescimento e desenvolvimento
Aedes / parasitologia
Envelhecido
Idoso, 80 anos ou mais
Animais
Antígenos, Protozoários / sangue
Brasil
Estudos Cross-Over
Culex / crescimento e desenvolvimento
Culex / parasitologia
Transmissão de Doenças Infecciosas
Filariose Linfática / epidemiologia
Entomologia / métodos
Monitorização Epidemiológica
Fêmea
Humanos
Imunoensaio
Masculino
Meia idade
Reação em Cadeia da Polimerase
Prevalência
População urbana
Wuchereria bancrofti / genética
Wuchereria bancrofti / isolamento e purificação
05 Igualdade de gênero
11 Cidades e comunidades sustentáveis
dc.subject.decs.none.fl_str_mv Adulto
Aedes / crescimento e desenvolvimento
Aedes / parasitologia
Envelhecido
Idoso, 80 anos ou mais
Animais
Antígenos, Protozoários / sangue
Brasil
Estudos Cross-Over
Culex / crescimento e desenvolvimento
Culex / parasitologia
Transmissão de Doenças Infecciosas
Filariose Linfática / epidemiologia
Entomologia / métodos
Monitorização Epidemiológica
Fêmea
Humanos
Imunoensaio
Masculino
Meia idade
Reação em Cadeia da Polimerase
Prevalência
População urbana
Wuchereria bancrofti / genética
Wuchereria bancrofti / isolamento e purificação
dc.subject.ods.none.fl_str_mv 05 Igualdade de gênero
11 Cidades e comunidades sustentáveis
description Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Parasitologia. Recife, PE, Brasil / London School of Hygiene & Tropical Medicine (LSHTM). Department of Infectious Disease Epidemiology. London, United Kingdom.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-04-04T13:47:11Z
dc.date.available.fl_str_mv 2019-04-04T13:47:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv RAMESH, A. et al. Development of an Urban Molecular Xenomonitoring System for Lymphatic Filariasis in the Recife Metropolitan Region, Brazil. PLoS Neglected Tropical Diseases, v. 12, n. 10, p. 1-24, 2018.
dc.identifier.uri.fl_str_mv https://arca.fiocruz.br/handle/icict/32360
dc.identifier.issn.none.fl_str_mv 1935-2735
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0006816
identifier_str_mv RAMESH, A. et al. Development of an Urban Molecular Xenomonitoring System for Lymphatic Filariasis in the Recife Metropolitan Region, Brazil. PLoS Neglected Tropical Diseases, v. 12, n. 10, p. 1-24, 2018.
1935-2735
10.1371/journal.pntd.0006816
url https://arca.fiocruz.br/handle/icict/32360
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://arca.fiocruz.br/bitstreams/4fdf029f-c279-44c8-a373-126d2a91522e/download
https://arca.fiocruz.br/bitstreams/7cfadda5-7c75-4e42-9594-e603ee371db9/download
https://arca.fiocruz.br/bitstreams/159fd451-fc27-4bc2-adab-a0c0ad40a76e/download
https://arca.fiocruz.br/bitstreams/73e2812d-5270-44fb-8e28-b968cb3d2ea6/download
bitstream.checksum.fl_str_mv ee3692f7b0b97d5638099ab94397d05f
e56c3d921c9426abaedddd1b78e740f0
7712d822c19f9f07f189e085a8f42e91
0dfb8be7e633b4502abeb3e7d0c328b8
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1839715829133869056

Similar Items