Direct immunofluorescence in Lupus Erythematosus (LE)

• Main Author: Isfer, Roseli Svartman
• Publication Date: 1996
• Other Authors: Sanches Jr., José Antônio, Festa Neto, Cyro, Cernea, Selma Schuartz, Oliveira, Zilda Najjar Prado de, Vilela, Maria Apparecida Constantino, Silva, Maria Luiza, Miyachi, Lucy Massaco, Fukumori, Ligia Maria Ishimura, Silva, Soraia Regina da
• Format: Article
• Language: eng
• Source: São Paulo medical journal (Online)
• Download full: https://periodicosapm.emnuvens.com.br/spmj/article/view/1889
• topic: Direct immunofluorescence (DIF); Lupus erythematosus (LE); Discoid lupus erythematosus (DLE); Subacute lupus erythematosus (SALE); Systemic lupus erythematosus (SLE); Immunoglobulins (Igs)

One hundred and twenty-six patients with LE were studied. They were distributed as follows: 84 with DLE, 13 with SALE and 29 with SLE. Biopsies from the skin lesions were performed and submitted to DIE Positive results were equal to 69, 61.5 and 72.4 percent of the DLE, SALE and SLE cases, respectively. These data are in accordance with the literature. IgM was the most frequently found immunoglobulin, followed by the association IgM+C3.