Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract

Bibliographic Details
Main Author: Antonio, Jamile Karina
Publication Date: 2008
Other Authors: Menezes, Marcelo Benedito, Kavabata, Norberto Kodi, Bertelli, Antonio Augusto Tupinambá, Kikuchi, William, Gonçalves, Antonio José
Format: Article
Language: eng
Source: São Paulo medical journal (Online)
Download full: https://periodicosapm.emnuvens.com.br/spmj/article/view/1947
Summary: CONTEXT AND OBJECTIVE: Modifi ed radical neck dissection (MRND) is the classical treatment for neck metastases of squamous cell carcinoma (SCC) of the upper aerodigestive tract. However, it may still be accompanied by signifi cant sequelae. One alternative for this treatment would be selective neck dissection (SND), which has a lower incidence of sequelae. The aim of this study was to defi ne which neck metastasis cases would really be suitable candidates for SND. DESIGN AND SETTING: Retrospective clinicalsurgical trial at the Division of Head and Neck Surgery, Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP). METHODS: We retrospectively studied 67 patients with SCC of the upper aerodigestive tract, divided into two groups: 1) 47 patients treated by means of SND (node-negative or node-positive), 2) 20 patients treated by means of MRND (all node-positive). RESULTS: Our results demonstrated that there was no difference between the patients treated with SND or MRND in relation to disease evolution, and that the main prognostic factor was lymph node involvement. We observed that patients with pharyngeal SCC and older patients presented worse evolution and would probably not be suitable candidates for SND. CONCLUSIONS: SND may be a good option for treating node-positive necks in selected cases.
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spelling Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract Esvaziamento cervical seletivo para o tratamento do pescoço positivo em carcinomas epidermóides do trato aerodigestório altoEsvaziamento cervicalNeoplasias de cabeça e pescoçoCarcinoma de células escamosasPrognósticoMetástase linfáticaNeck dissectionHead and neck neoplasmsCarcinoma, squamous cellPrognosisLymphatic metastasisCONTEXT AND OBJECTIVE: Modifi ed radical neck dissection (MRND) is the classical treatment for neck metastases of squamous cell carcinoma (SCC) of the upper aerodigestive tract. However, it may still be accompanied by signifi cant sequelae. One alternative for this treatment would be selective neck dissection (SND), which has a lower incidence of sequelae. The aim of this study was to defi ne which neck metastasis cases would really be suitable candidates for SND. DESIGN AND SETTING: Retrospective clinicalsurgical trial at the Division of Head and Neck Surgery, Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP). METHODS: We retrospectively studied 67 patients with SCC of the upper aerodigestive tract, divided into two groups: 1) 47 patients treated by means of SND (node-negative or node-positive), 2) 20 patients treated by means of MRND (all node-positive). RESULTS: Our results demonstrated that there was no difference between the patients treated with SND or MRND in relation to disease evolution, and that the main prognostic factor was lymph node involvement. We observed that patients with pharyngeal SCC and older patients presented worse evolution and would probably not be suitable candidates for SND. CONCLUSIONS: SND may be a good option for treating node-positive necks in selected cases.CONTEXTO E OBJETIVO: O esvaziamento cervical radical modificado (ECRM) é o tratamento clássico para as metástases cervicais do carcinoma espinocelular (CEC) do trato aerodigestório alto (TADA). Este procedimento é considerado oncologicamente satisfatório, porém pode ser acompanhado de seqüelas significativas devido à extensão do procedimento e a grande manipulação de estruturas nobres, especialmente as nervosas. Assim, tem sido proposto o esvaziamento cervical seletivo (ECS) para o tratamento de casos selecionados, pN1, pN2 sem ruptura capsular, minimizando, ou mesmo evitando, deste modo, as seqüelas do ECRM. O grande questionamento atual é a definição de quais casos seriam eleitos para este procedimento, sem alterar o resultado oncológico de médio e longo prazo. TIPO DE ESTUDO E LOCAL: Estudo clínico retrospectivo realizado na Disciplina de Cirurgia de Cabeça e Pescoço do Departamento de Cirurgia da Faculdade de Ciências Médicas da Santa Casa de São Paulo. MÉTODOS: Estudamos 67 doentes portadores de CEC do TADA de 1990 a 2001 dividindo-os em dois grupos: 1) 47 doentes tratados com ECS e 2) 20 doentes tratados com ECRM (todos N+). Os casos do grupo 1 eram clinicamente N0 e, 11 tornaram-se pN+, após o exame histopatológico. Assim, no grupo 1 obtivemos doentes pN+ tratados com ECS e seguimos estes grupos por, no mínimo, 2 anos. O grupo 2 serviu como controle da evolução dos doentes pN+. RESULTADOS: Nossos resultados mostraram que na comparação do ECS com o ECRM, não houve diferença significativa quanto à evolução (sobrevivência ou recidiva), no entanto, foi possível evidenciar uma pior evolução nos doentes N+ quando comparados aos N0, demonstrando que o principal fator prognóstico é o comprometimento linfonodal. Além disso, apesar do pequeno número de doentes, observamos que os doentes mais idosos e com CEC de faringe tiveram pior evolução e, por isto, talvez não sejam candidatos ao ECS. CONCLUSÕES: Concluímos, portanto, que o ECS pode ser uma boa opção de tratamento no pescoço N+, em casos selecionados, com metástases cervicais limitadas.São Paulo Medical JournalSão Paulo Medical Journal2008-03-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicosapm.emnuvens.com.br/spmj/article/view/1947São Paulo Medical Journal; Vol. 126 No. 2 (2008); 112-118São Paulo Medical Journal; v. 126 n. 2 (2008); 112-1181806-9460reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APMenghttps://periodicosapm.emnuvens.com.br/spmj/article/view/1947/1845https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAntonio, Jamile KarinaMenezes, Marcelo BeneditoKavabata, Norberto KodiBertelli, Antonio Augusto TupinambáKikuchi, WilliamGonçalves, Antonio José2023-09-20T17:41:36Zoai:ojs.diagnosticoetratamento.emnuvens.com.br:article/1947Revistahttp://www.scielo.br/spmjPUBhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2023-09-20T17:41:36São Paulo medical journal (Online) - Associação Paulista de Medicinafalse
dc.title.none.fl_str_mv Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract
Esvaziamento cervical seletivo para o tratamento do pescoço positivo em carcinomas epidermóides do trato aerodigestório alto
title Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract
spellingShingle Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract
Antonio, Jamile Karina
Esvaziamento cervical
Neoplasias de cabeça e pescoço
Carcinoma de células escamosas
Prognóstico
Metástase linfática
Neck dissection
Head and neck neoplasms
Carcinoma, squamous cell
Prognosis
Lymphatic metastasis
title_short Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract
title_full Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract
title_fullStr Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract
title_full_unstemmed Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract
title_sort Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract
author Antonio, Jamile Karina
author_facet Antonio, Jamile Karina
Menezes, Marcelo Benedito
Kavabata, Norberto Kodi
Bertelli, Antonio Augusto Tupinambá
Kikuchi, William
Gonçalves, Antonio José
author_role author
author2 Menezes, Marcelo Benedito
Kavabata, Norberto Kodi
Bertelli, Antonio Augusto Tupinambá
Kikuchi, William
Gonçalves, Antonio José
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Antonio, Jamile Karina
Menezes, Marcelo Benedito
Kavabata, Norberto Kodi
Bertelli, Antonio Augusto Tupinambá
Kikuchi, William
Gonçalves, Antonio José
dc.subject.por.fl_str_mv Esvaziamento cervical
Neoplasias de cabeça e pescoço
Carcinoma de células escamosas
Prognóstico
Metástase linfática
Neck dissection
Head and neck neoplasms
Carcinoma, squamous cell
Prognosis
Lymphatic metastasis
topic Esvaziamento cervical
Neoplasias de cabeça e pescoço
Carcinoma de células escamosas
Prognóstico
Metástase linfática
Neck dissection
Head and neck neoplasms
Carcinoma, squamous cell
Prognosis
Lymphatic metastasis
description CONTEXT AND OBJECTIVE: Modifi ed radical neck dissection (MRND) is the classical treatment for neck metastases of squamous cell carcinoma (SCC) of the upper aerodigestive tract. However, it may still be accompanied by signifi cant sequelae. One alternative for this treatment would be selective neck dissection (SND), which has a lower incidence of sequelae. The aim of this study was to defi ne which neck metastasis cases would really be suitable candidates for SND. DESIGN AND SETTING: Retrospective clinicalsurgical trial at the Division of Head and Neck Surgery, Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP). METHODS: We retrospectively studied 67 patients with SCC of the upper aerodigestive tract, divided into two groups: 1) 47 patients treated by means of SND (node-negative or node-positive), 2) 20 patients treated by means of MRND (all node-positive). RESULTS: Our results demonstrated that there was no difference between the patients treated with SND or MRND in relation to disease evolution, and that the main prognostic factor was lymph node involvement. We observed that patients with pharyngeal SCC and older patients presented worse evolution and would probably not be suitable candidates for SND. CONCLUSIONS: SND may be a good option for treating node-positive necks in selected cases.
publishDate 2008
dc.date.none.fl_str_mv 2008-03-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicosapm.emnuvens.com.br/spmj/article/view/1947
url https://periodicosapm.emnuvens.com.br/spmj/article/view/1947
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicosapm.emnuvens.com.br/spmj/article/view/1947/1845
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv São Paulo Medical Journal
São Paulo Medical Journal
publisher.none.fl_str_mv São Paulo Medical Journal
São Paulo Medical Journal
dc.source.none.fl_str_mv São Paulo Medical Journal; Vol. 126 No. 2 (2008); 112-118
São Paulo Medical Journal; v. 126 n. 2 (2008); 112-118
1806-9460
reponame:São Paulo medical journal (Online)
instname:Associação Paulista de Medicina
instacron:APM
instname_str Associação Paulista de Medicina
instacron_str APM
institution APM
reponame_str São Paulo medical journal (Online)
collection São Paulo medical journal (Online)
repository.name.fl_str_mv São Paulo medical journal (Online) - Associação Paulista de Medicina
repository.mail.fl_str_mv revistas@apm.org.br
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