Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract
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Publication Date: | 2008 |
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Format: | Article |
Language: | eng |
Source: | São Paulo medical journal (Online) |
Download full: | https://periodicosapm.emnuvens.com.br/spmj/article/view/1947 |
Summary: | CONTEXT AND OBJECTIVE: Modifi ed radical neck dissection (MRND) is the classical treatment for neck metastases of squamous cell carcinoma (SCC) of the upper aerodigestive tract. However, it may still be accompanied by signifi cant sequelae. One alternative for this treatment would be selective neck dissection (SND), which has a lower incidence of sequelae. The aim of this study was to defi ne which neck metastasis cases would really be suitable candidates for SND. DESIGN AND SETTING: Retrospective clinicalsurgical trial at the Division of Head and Neck Surgery, Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP). METHODS: We retrospectively studied 67 patients with SCC of the upper aerodigestive tract, divided into two groups: 1) 47 patients treated by means of SND (node-negative or node-positive), 2) 20 patients treated by means of MRND (all node-positive). RESULTS: Our results demonstrated that there was no difference between the patients treated with SND or MRND in relation to disease evolution, and that the main prognostic factor was lymph node involvement. We observed that patients with pharyngeal SCC and older patients presented worse evolution and would probably not be suitable candidates for SND. CONCLUSIONS: SND may be a good option for treating node-positive necks in selected cases. |
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Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract Esvaziamento cervical seletivo para o tratamento do pescoço positivo em carcinomas epidermóides do trato aerodigestório altoEsvaziamento cervicalNeoplasias de cabeça e pescoçoCarcinoma de células escamosasPrognósticoMetástase linfáticaNeck dissectionHead and neck neoplasmsCarcinoma, squamous cellPrognosisLymphatic metastasisCONTEXT AND OBJECTIVE: Modifi ed radical neck dissection (MRND) is the classical treatment for neck metastases of squamous cell carcinoma (SCC) of the upper aerodigestive tract. However, it may still be accompanied by signifi cant sequelae. One alternative for this treatment would be selective neck dissection (SND), which has a lower incidence of sequelae. The aim of this study was to defi ne which neck metastasis cases would really be suitable candidates for SND. DESIGN AND SETTING: Retrospective clinicalsurgical trial at the Division of Head and Neck Surgery, Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP). METHODS: We retrospectively studied 67 patients with SCC of the upper aerodigestive tract, divided into two groups: 1) 47 patients treated by means of SND (node-negative or node-positive), 2) 20 patients treated by means of MRND (all node-positive). RESULTS: Our results demonstrated that there was no difference between the patients treated with SND or MRND in relation to disease evolution, and that the main prognostic factor was lymph node involvement. We observed that patients with pharyngeal SCC and older patients presented worse evolution and would probably not be suitable candidates for SND. CONCLUSIONS: SND may be a good option for treating node-positive necks in selected cases.CONTEXTO E OBJETIVO: O esvaziamento cervical radical modificado (ECRM) é o tratamento clássico para as metástases cervicais do carcinoma espinocelular (CEC) do trato aerodigestório alto (TADA). Este procedimento é considerado oncologicamente satisfatório, porém pode ser acompanhado de seqüelas significativas devido à extensão do procedimento e a grande manipulação de estruturas nobres, especialmente as nervosas. Assim, tem sido proposto o esvaziamento cervical seletivo (ECS) para o tratamento de casos selecionados, pN1, pN2 sem ruptura capsular, minimizando, ou mesmo evitando, deste modo, as seqüelas do ECRM. O grande questionamento atual é a definição de quais casos seriam eleitos para este procedimento, sem alterar o resultado oncológico de médio e longo prazo. TIPO DE ESTUDO E LOCAL: Estudo clínico retrospectivo realizado na Disciplina de Cirurgia de Cabeça e Pescoço do Departamento de Cirurgia da Faculdade de Ciências Médicas da Santa Casa de São Paulo. MÉTODOS: Estudamos 67 doentes portadores de CEC do TADA de 1990 a 2001 dividindo-os em dois grupos: 1) 47 doentes tratados com ECS e 2) 20 doentes tratados com ECRM (todos N+). Os casos do grupo 1 eram clinicamente N0 e, 11 tornaram-se pN+, após o exame histopatológico. Assim, no grupo 1 obtivemos doentes pN+ tratados com ECS e seguimos estes grupos por, no mínimo, 2 anos. O grupo 2 serviu como controle da evolução dos doentes pN+. RESULTADOS: Nossos resultados mostraram que na comparação do ECS com o ECRM, não houve diferença significativa quanto à evolução (sobrevivência ou recidiva), no entanto, foi possível evidenciar uma pior evolução nos doentes N+ quando comparados aos N0, demonstrando que o principal fator prognóstico é o comprometimento linfonodal. Além disso, apesar do pequeno número de doentes, observamos que os doentes mais idosos e com CEC de faringe tiveram pior evolução e, por isto, talvez não sejam candidatos ao ECS. CONCLUSÕES: Concluímos, portanto, que o ECS pode ser uma boa opção de tratamento no pescoço N+, em casos selecionados, com metástases cervicais limitadas.São Paulo Medical JournalSão Paulo Medical Journal2008-03-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicosapm.emnuvens.com.br/spmj/article/view/1947São Paulo Medical Journal; Vol. 126 No. 2 (2008); 112-118São Paulo Medical Journal; v. 126 n. 2 (2008); 112-1181806-9460reponame:São Paulo medical journal (Online)instname:Associação Paulista de Medicinainstacron:APMenghttps://periodicosapm.emnuvens.com.br/spmj/article/view/1947/1845https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAntonio, Jamile KarinaMenezes, Marcelo BeneditoKavabata, Norberto KodiBertelli, Antonio Augusto TupinambáKikuchi, WilliamGonçalves, Antonio José2023-09-20T17:41:36Zoai:ojs.diagnosticoetratamento.emnuvens.com.br:article/1947Revistahttp://www.scielo.br/spmjPUBhttps://old.scielo.br/oai/scielo-oai.phprevistas@apm.org.br1806-94601516-3180opendoar:2023-09-20T17:41:36São Paulo medical journal (Online) - Associação Paulista de Medicinafalse |
dc.title.none.fl_str_mv |
Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract Esvaziamento cervical seletivo para o tratamento do pescoço positivo em carcinomas epidermóides do trato aerodigestório alto |
title |
Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract |
spellingShingle |
Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract Antonio, Jamile Karina Esvaziamento cervical Neoplasias de cabeça e pescoço Carcinoma de células escamosas Prognóstico Metástase linfática Neck dissection Head and neck neoplasms Carcinoma, squamous cell Prognosis Lymphatic metastasis |
title_short |
Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract |
title_full |
Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract |
title_fullStr |
Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract |
title_full_unstemmed |
Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract |
title_sort |
Selective neck dissection for treating node-positive necks in cases of squamous cell carcinoma of the upper aerodigestive tract |
author |
Antonio, Jamile Karina |
author_facet |
Antonio, Jamile Karina Menezes, Marcelo Benedito Kavabata, Norberto Kodi Bertelli, Antonio Augusto Tupinambá Kikuchi, William Gonçalves, Antonio José |
author_role |
author |
author2 |
Menezes, Marcelo Benedito Kavabata, Norberto Kodi Bertelli, Antonio Augusto Tupinambá Kikuchi, William Gonçalves, Antonio José |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Antonio, Jamile Karina Menezes, Marcelo Benedito Kavabata, Norberto Kodi Bertelli, Antonio Augusto Tupinambá Kikuchi, William Gonçalves, Antonio José |
dc.subject.por.fl_str_mv |
Esvaziamento cervical Neoplasias de cabeça e pescoço Carcinoma de células escamosas Prognóstico Metástase linfática Neck dissection Head and neck neoplasms Carcinoma, squamous cell Prognosis Lymphatic metastasis |
topic |
Esvaziamento cervical Neoplasias de cabeça e pescoço Carcinoma de células escamosas Prognóstico Metástase linfática Neck dissection Head and neck neoplasms Carcinoma, squamous cell Prognosis Lymphatic metastasis |
description |
CONTEXT AND OBJECTIVE: Modifi ed radical neck dissection (MRND) is the classical treatment for neck metastases of squamous cell carcinoma (SCC) of the upper aerodigestive tract. However, it may still be accompanied by signifi cant sequelae. One alternative for this treatment would be selective neck dissection (SND), which has a lower incidence of sequelae. The aim of this study was to defi ne which neck metastasis cases would really be suitable candidates for SND. DESIGN AND SETTING: Retrospective clinicalsurgical trial at the Division of Head and Neck Surgery, Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP). METHODS: We retrospectively studied 67 patients with SCC of the upper aerodigestive tract, divided into two groups: 1) 47 patients treated by means of SND (node-negative or node-positive), 2) 20 patients treated by means of MRND (all node-positive). RESULTS: Our results demonstrated that there was no difference between the patients treated with SND or MRND in relation to disease evolution, and that the main prognostic factor was lymph node involvement. We observed that patients with pharyngeal SCC and older patients presented worse evolution and would probably not be suitable candidates for SND. CONCLUSIONS: SND may be a good option for treating node-positive necks in selected cases. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-03-03 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicosapm.emnuvens.com.br/spmj/article/view/1947 |
url |
https://periodicosapm.emnuvens.com.br/spmj/article/view/1947 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicosapm.emnuvens.com.br/spmj/article/view/1947/1845 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
São Paulo Medical Journal São Paulo Medical Journal |
publisher.none.fl_str_mv |
São Paulo Medical Journal São Paulo Medical Journal |
dc.source.none.fl_str_mv |
São Paulo Medical Journal; Vol. 126 No. 2 (2008); 112-118 São Paulo Medical Journal; v. 126 n. 2 (2008); 112-118 1806-9460 reponame:São Paulo medical journal (Online) instname:Associação Paulista de Medicina instacron:APM |
instname_str |
Associação Paulista de Medicina |
instacron_str |
APM |
institution |
APM |
reponame_str |
São Paulo medical journal (Online) |
collection |
São Paulo medical journal (Online) |
repository.name.fl_str_mv |
São Paulo medical journal (Online) - Associação Paulista de Medicina |
repository.mail.fl_str_mv |
revistas@apm.org.br |
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1825135070004903936 |